Role of corticotrophin-releasing factor in the stress-induced dilation of esophageal intercellular spaces

Journal of Korean Medical Science

Volumn 26, Issue 2, 2011, Pages 279-283

  Cho, Young Ju ^a   Kim, Jang Hee ^a   Yim, Hyun Ee ^a   Lee, Da Mi ^a   Im, Seon Kyo ^a   Lee, Kwang Jae ^a  

^a Ajou University School of Medicine   (South Korea)

Author keywords

Corticotropin Releasing hormone; Esophagus; Extracellular space; Stress

Indexed keywords

ASTRESSIN; CORTICOTROPIN RELEASING FACTOR; HYDROCORTISONE; NEUROPROTECTIVE AGENT; PEPTIDE FRAGMENT;

ANIMAL; ARTICLE; BLOOD; DRUG ANTAGONISM; DRUG EFFECT; ESOPHAGUS; EXTRACELLULAR SPACE; HISTOLOGY; MALE; MENTAL STRESS; METABOLISM; MUCOSA; PATHOPHYSIOLOGY; RAT; WISTAR RAT;

ANIMALS; CORTICOTROPIN-RELEASING HORMONE; ESOPHAGUS; EXTRACELLULAR SPACE; HYDROCORTISONE; MALE; MUCOUS MEMBRANE; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; STRESS, PSYCHOLOGICAL;

EID: 79551664684     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2011.26.2.279     Document Type: Article

References (30)

1. Grammatopoulos DK, Chrousos GP. Functional characteristics of CRH receptors and potential clinical applications of CRH-receptor antagonists. Trends Endocrinol Metab 2002; 13: 436-44.
2. Heinrichs SC, De Souza EB. Corticotropin-releasing factor antagonists, binding-protein and receptors: implications for central nervous system disorders. Baillieres Best Pract Res Clin Endocrinol Metab 1999; 13: 541-54.
3. Chrousos GP. Stress, chronic inflammation, and emotional and physical well-being: concurrent effects and chronic sequelae. J Allergy Clin Immunol 2000; 106 (5 Suppl): S275-91.
4. Taché Y, Perdue MH. Role of peripheral CRF signalling pathways in stressrelated alterations of gut motility and mucosal function. Neurogastroenterol Motil 2004; 16 Suppl 1: 137-42.
5. Taché Y, Bonaz B. Corticotropin-releasing factor receptors and stress-related alterations of gut motor function. J Clin Invest 2007; 117: 33-40.
6. Farré R, De Vos R, Geboes K, Verbecke K, Vanden Berghe P, Depoortere I, Blondeau K, Tack J, Sifrim D. Critical role of stress in increased oesophageal mucosa permeability and dilated intercellular spaces. Gut 2007; 56: 1191-7.
7. Kim DH, Cho YJ, Kim JH, Kim YB, Lee KJ. Stress-induced alterations in mast cell numbers and proteinase-activated receptor-2 expression of the colon: role of corticotrophin-releasing factor. J Korean Med Sci 2010; 25: 1330-5.
8. Caviglia R, Ribolsi M, Maggiano N, Gabbrielli AM, Emerenziani S, Guarino MP, Carotti S, Habib FI, Rabitti C, Cicala M. Dilated intercellular spaces of esophageal epithelium in nonerosive reflux disease patients with physiological esophageal acid exposure. Am J Gastroenterol 2005; 100: 543-8.
9. Cui RL, Zhou LY, Lin SR, Xue Y. A study on the light microscopic measurement of intercellular space of squamous epithelium in lower-esophagus to diagnose gastroesophageal reflux disease. Zhonghua Nei Ke Za Zhi 2009; 48: 208-12.
10. van Malenstein H, Farré R, Sifrim D. Esophageal dilated intercellular spaces (DIS) and nonerosive reflux disease. Am J Gastroenterol 2008; 103: 1021-8.
11. Barlow WJ, Orlando RC. The pathogenesis of heartburn in nonerosive reflux disease: a unifying hypothesis. Gastroenterology 2005; 128: 771-8.
12. Bove M, Vieth M, Dombrowski F, Ny L, Ruth M, Lundell L. Acid challenge to the human esophageal mucosa: effects on epithelial architecture in health and disease. Dig Dis Sci 2005; 50: 1488-96.
13. Bradley LA, Richter JE, Pulliam TJ, Haile JM, Scarinci IC, Schan CA, Dalton CB, Salley AN. The relationship between stress and symptoms of gastroesophageal reflux: the influence of psychological factors. Am J Gastroenterol 1993; 88: 11-9.
14. Naliboff BD, Mayer M, Fass R, Fitzgerald LZ, Chang L, Bolus R, Mayer EA. The effect of life stress on symptoms of heartburn. Psychosom Med 2004; 66: 426-34.
15. Fass R, Naliboff BD, Fass SS, Peleg N, Wendel C, Malagon IB, Mayer EA. The effect of auditory stress on perception of intraesophageal acid in patients with gastroesophageal reflux disease. Gastroenterology 2008; 134: 696-705.
16. Perrin MH, Vale WW. Corticotropin releasing factor receptors and their ligand family. Ann N Y Acad Sci 1999; 885: 312-28.
17. Teitelbaum AA, Gareau MG, Jury J, Yang PC, Perdue MH. Chronic peripheral administration of corticotropin-releasing factor causes colonic barrier dysfunction similar to psychological stress. Am J Physiol Gastrointest Liver Physiol 2008; 295: G452-9.
18. Santos J, Saunders PR, Hanssen NP, Yang PC, Yates D, Groot JA, Perdue MH. Corticotropin-releasing hormone mimics stress-induced colonic epithelial pathophysiology in the rat. Am J Physiol 1999; 277: G391-9.
19. Gulyas J, Rivier C, Perrin M, Koerber SC, Sutton S, Corrigan A, Lahrichi SL, Craig AG, Vale W, Rivier J. Potent, structurally constrained agonists and competitive antagonists of corticotropin-releasing factor. Proc Natl Acad Sci USA 1995; 92: 10575-9.
20. Bale TL, Vale WW. CRF and CRF receptors: role in stress responsivity and other behaviors. Annu Rev Pharmacol Toxicol 2004; 44: 525-57.
21. Kehne J, De Lombaert S. Non-peptidic CRF1 receptor antagonists for the treatment of anxiety, depression and stress disorders. Curr Drug Targets CNS Neurol Disord 2002; 1: 467-93.
22. Yokotani K, Murakami Y, Okada S, Hirata M. Role of brain arachidonic acid cascade on central CRF1 receptor-mediated activation of sympathoadrenomedullary outflow in rats. Eur J Pharmacol 2001; 419: 183-9.
23. Taché Y, Million M, Nelson AG, Lamy C, Wang L. Role of corticotropinreleasing factor pathways in stress-related alterations of colonic motor function and viscerosensibility in female rodents. Gend Med 2005; 2: 146-54.
24. Taché Y, Martinez V, Wang L, Million M. CRF1 receptor signaling pathways are involved in stress-related alterations of colonic function and viscerosensitivity: implications for irritable bowel syndrome. Br J Pharmacol 2004; 141: 1321-30.
25. Hauger RL, Grigoriadis DE, Dallman MF, Plotsky PM, Vale WW, Dautzenberg FM. International Union of Pharmacology. XXXVI. Current status of the nomenclature for receptors for corticotropin-releasing factor and their ligands. Pharmacol Rev 2003; 55: 21-6.
26. Gué M, Del Rio-Lacheze C, Eutamene H, Théodorou V, Fioramonti J, Buéno L. Stress-induced visceral hypersensitivity to rectal distension in rats: role of CRF and mast cells. Neurogastroenterol Motil 1997; 9: 271-9.
27. Williams CL, Villar RG, Peterson JM, Burks TF. Stress-induced changes in intestinal transit in the rat: a model for irritable bowel syndrome. Gastroenterology 1988; 94: 611-21.
28. Strausbaugh HJ, Dallman MF, Levine JD. Repeated, but not acute, stress suppresses inflammatory plasma extravasation. Proc Natl Acad Sci USA 1999; 96: 14629-34.
29. Wallon C, Yang PC, Keita AV, Ericson AC, McKay DM, Sherman PM, Perdue MH, Söderholm JD. Corticotropin-releasing hormone (CRH) regulates macromolecular permeability via mast cells in normal human colonic biopsies in vitro. Gut 2008; 57: 50-8.
30. Wallon C, Söderholm JD. Corticotropin-releasing hormone and mast cells in the regulation of mucosal barrier function in the human colon. Ann N Y Acad Sci 2009; 1165: 206-10.