Stress-induced alterations in mast cell numbers and proteinaseactivated receptor-2 expression of the colon: Role of corticotrophin-releasing factor

Journal of Korean Medical Science

Volumn 25, Issue 9, 2010, Pages 1330-1335

  Kim, Dong Hoon ^a   Cho, Young Ju ^a   Kim, Jang Hee ^a   Kim, Young Bae ^a   Lee, Kwang Jae ^a  

^a Ajou University School of Medicine   (South Korea)

Author keywords

Corticotropin releasing factor; Enterochromaffin cells; Irritable bowel syndrome; Mast cells; PAR 2; Receptor; Stress

Indexed keywords

ASTRESSIN; CORTICOTROPIN RELEASING FACTOR; PEPTIDE FRAGMENT; PROTEINASE ACTIVATED RECEPTOR 2;

ANIMAL; ARTICLE; COLON; CYTOLOGY; DRUG ANTAGONISM; ENTEROCHROMAFFIN CELL; EXERCISE; IMMUNOLOGY; MALE; MAST CELL; METABOLISM; PHYSIOLOGICAL STRESS; PHYSIOLOGY; RAT; WISTAR RAT;

ANIMALS; COLON; CORTICOTROPIN-RELEASING HORMONE; ENTEROCHROMAFFIN CELLS; MALE; MAST CELLS; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; RECEPTOR, PAR-2; RESTRAINT, PHYSICAL; STRESS, PHYSIOLOGICAL;

EID: 77956510712     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2010.25.9.1330     Document Type: Article

References (30)

1. Fukudo S. Role of corticotrophin-releasing hormone in irritable bowel syndrome and intestinal inflammation. J Gastroenterol 2007; 42 Suppl 17: 48-51.
2. Gue M, Del Rio-Lacheze C, Eutamene H, Theodorou V, Fioramonti J, Bueno L. Stress-induced visceral hypersensitivity to rectal distension in rats: role of CRF and mast cells. Neurogastroenterol Motil 1997; 9: 271-9.
3. Monnikes H, Schmidt BG, Tache Y. Psychological stress-induced accelerated colonic transit in rats involves hypothalamic corticotropin-releasing factor. Gastroenterology 1993; 104: 716-23.
4. Williams CL, Peterson JM, Villar RG, Burks TF. Corticotropin-releasing factor directly mediates colonic responses to stress. Am J Physiol 1987; 253: G582-6.
5. Williams CL, Villar RG, Peterson JM, Burks TF. Stress-induced changes in intestinal transit in the rat: a model for irritable bowel syndrome. Gastroenterology 1988; 94: 611-21.
6. Lenz HJ, Raedler A, Greten H, Vale WW, Rivier JE. Stress-induced gastrointestinal secretory and motor responses in rats are mediated by endogenous corticotrophin-releasing factor. Gastroenterology 1988; 95: 1510-7.
7. Sant GR, Theoharides TC. The role of the mast cell in interstitial cystitis. Urol Clin North Am 1994; 21: 41-53.
8. Castagliuolo I, Lamont JT, Qiu B, Fleming SM, Bhaskar KR, Nikulasson ST, Kornetsky C, Pothoulakis C. Acute stress causes mucin release from rat colon: role of corticotrophin releasing factor and mast cells. Am J Physiol 1996; 271: G884-92.
9. Annese V, Bassotti G, Napolitano G, Usai P, Andriulli A, Vantrappen G. Gastrointestinal motility disorders in patients with inactive Crohn's disease. Scand J Gastroenterol 1997; 32: 1107-17.
10. Vermillion DL, Huizinga JD, Riddell RH, Collins SM. Altered small intestinal smooth muscle function in Crohn's disease. Gastroenterology 1993; 104: 1692-9.
11. Dunlop SP, Jenkins D, Neal KR, Spiller RC. Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS. Gastroenterology 2003; 125: 1651-9.
12. Lee KJ, Kim YB, Kim JH, Kwon HC, Kim DK, Cho SW. The alteration of enterochromaffin cell, mast cell, and lamina propria T lymphocyte numbers in irritable bowel syndrome and its relationship with psychological factors. J Gastroenterol Hepatol 2008; 23: 1689-94.
13. Park CH, Joo YE, Choi SK, Rew JS, Kim SJ, Lee MC. Activated mast cells infiltrate in close proximity to enteric nerves in diarrhea-predominant irritable bowel syndrome. J Korean Med Sci 2003; 18: 204-10.
14. Dunlop SP, Jenkins D, Spiller RC. Distinctive clinical, psychological, and histological features of postinfective irritable bowel syndrome. Am J Gastroenterol 2003; 98: 1578-83.
15. Gué M, Del Rio-Lacheze C, Eutamene H, Théodorou V, Fioramonti J, Buéno L. Stress-induced visceral hypersensitivity to rectal distension in rats: role of CRF and mast cells. Neurogastroenterol Motil 1997; 9: 271-9.
16. Williams CL, Villar RG, Peterson JM, Burks TF. Stress-induced changes in intestinal transit in the rat: a model for irritable bowel syndrome. Gastroenterology 1988; 94: 611-21.
17. Strausbaugh HJ, Dallman MF, Levine JD. Repeated, but not acute, stress suppresses inflammatory plasma extravasation. Proc Natl Acad Sci USA 1999; 96: 14629-34.
18. Barone FC, Deegan JF, Price WJ, Fowler PJ, Fondacaro JD, Ormsbee HS 3rd. Cold-restraint stress increases rat fecal pellet output and colonic transit. Am J Physiol 1990; 258: G329-37.
19. Singh VK. Stimulatory effect of corticotrophin-releasing neurohormone on human lymphocyte proliferation and interleukin-2 receptor expression. J Neuroimmunol 1989; 23: 257-62.
20. Webster EL, Tracey DE, Jutila MA, Wolfe SA Jr, De Souza EB. Corticotropin-releasing factor receptors in mouse spleen: identification of receptorbearing cells as resident macrophages. Endocrinology 1990; 127: 440-52.
21. Eutamene H, Theodorou V, Fioramonti J, Bueno L. Acute stress modulates the histamine content of mast cells in the gastrointestinal tract through interleukin-1 and corticotrophin-releasing factor release in rats. J Physiol 2003; 553: 959-66.
22. Park JH, Rhee PL, Kim HS, Lee JH, Kim YH, Kim JJ, Rhee JC. Mucosal mast cell counts correlate with visceral hypersensitivity in patients with diarrhea predominant irritable bowel syndrome. J Gastroenterol Hepatol 2006; 21: 71-8.
23. Barbara G, Stanghellini V, De Giorgio R, Cremon C, Cottrell GS, Santini D, Pasquinelli G, Morselli-Labate AM, Grady EF, Bunnett NW, Collins SM, Corinaldesi R. Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome. Gastroenterology 2004; 126: 693-702.
24. Bueno L, Fioramonti J, Delvaux M, Frexinos J. Mediators and pharmacology of visceral sensitivity: from basic to clinical investigations. Gastroenterology 1997; 112: 1714-43.
25. Nystedt S, Emilsson K, Larsson AK, Strombeck B, Sundelin J. Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2. Eur J Biochem 1995; 232: 84-9.
26. Vergnolle N, Bunnett NW, Sharkey KA, Brussee V, Compton SJ, Grady EF, Cirino G, Gerard N, Basbaum AI, Andrade-Gordon P, Hollenberg MD, Wallace JL. Proteinase-activated receptor-2 and hyperalgesia: a novel pain pathway. Nat Med 2001; 7: 821-6.
27. Vergnolle N. Clinical relevance of proteinase activated receptors (PARS) in the gut. Gut 2005; 54: 867-74.
28. Coelho AM, Vergnolle N, Guiard B, Fioramonti J, Bueno L. Proteinases and proteinase-activated receptor 2: a possible role to promote visceral hyperalgesia in rats. Gastroenterology 2002; 122: 1035-47.
29. Marshall JK, Thabane M, Garg AX, Clark W, Meddings J, Collins SM. WEL Investigators. Intestinal permeability in patients with irritable bowel syndrome after a waterborne outbreak of acute gastroenteritis in Walkerton, Ontario. Aliment Pharmacol Ther 2004; 20: 1317-22.
30. Gecse K, Roka R, Ferrier L, Leveque M, Eutamene H, Cartier C, Ait-Belgnaoui A, Rosztoczy A, Izbeki F, Fioramonti J, Wittmann T, Bueno L. Increased faecal serine protease activity in diarrhoeic IBS patients: a colonic luminal factor impairing colonic permeability and sensitivity. Gut 2008; 57: 591-9.