Simultaneous monitoring of tissue PO 2 and NADH fluorescence during synaptic stimulation and spreading depression reveals a transient dissociation between oxygen utilization and mitochondrial redox state in rat hippocampal slices

Journal of Cerebral Blood Flow and Metabolism

Volumn 31, Issue 2, 2011, Pages 626-639

  Galeffi, Francesca ^a,b   Somjen, George G ^a   Foster, Kelley A ^a,b   Turner, Dennis A ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DURHAM VA MEDICAL CENTER   (United States)

Author keywords

hippocampus; mitochondria; optical imaging; oxidative metabolism; oxygen sensor

Indexed keywords

ADENOSINE TRIPHOSPHATE; OXYGEN; POTASSIUM CHLORIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

AEROBIC METABOLISM; ANIMAL TISSUE; ARTICLE; ELECTROSTIMULATION; ENERGY METABOLISM; EXCITATORY POSTSYNAPTIC POTENTIAL; FLUORESCENCE; HIPPOCAMPUS; MALE; MITOCHONDRION; NONHUMAN; OXIDATION REDUCTION STATE; OXYGEN CONSUMPTION; OXYGEN SUPPLY; OXYGEN TISSUE LEVEL; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN; SPREADING CORTICAL DEPRESSION;

ANIMALS; CORTICAL SPREADING DEPRESSION; ELECTRIC STIMULATION; ELECTROPHYSIOLOGICAL PHENOMENA; EXCITATORY POSTSYNAPTIC POTENTIALS; FLUORESCENCE; HIPPOCAMPUS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MICROINJECTIONS; MITOCHONDRIA; NAD; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; POTASSIUM CHLORIDE; RATS; RATS, INBRED F344; STIMULATION, CHEMICAL; SYNAPSES;

EID: 79551619761     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2010.136     Document Type: Article

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