Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models

Human Molecular Genetics

Volumn 20, Issue 5, 2011, Pages 855-866

  Liu, Zhen ^a   Xie, Jian ^a   Wu, Tao ^a   Truong, Thao ^a   Auchus, Richard J ^b   Huang, Chou Long ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; ANGIOTENSIN II; PROTEIN KINASE KS WNK1; PROTEIN KINASE WNK1; SODIUM CHLORIDE COTRANSPORTER; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; UNCLASSIFIED DRUG;

ALDOSTERONE BLOOD LEVEL; ANGIOTENSIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; DOWN REGULATION; EXON; FEMALE; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION; HENLE LOOP; HIGH SODIUM INTAKE; KIDNEY; KIDNEY DISTAL TUBULE; MALE; MOUSE; NEPHRON; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SALT WASTING; SODIUM RETENTION; TRANSGENIC MOUSE; WILD TYPE; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION; GENE SILENCING; HUMANS; KIDNEY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PSEUDOHYPOALDOSTERONISM; RECEPTORS, DRUG; SODIUM; SODIUM-POTASSIUM-CHLORIDE SYMPORTERS; SYMPORTERS;

MUS; MUS MUSCULUS;

EID: 79551604642     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq525     Document Type: Article

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