Capsaicinoids-induced changes of plasma glucose, free fatty acid and glycerol concentrations in rats

Journal of Toxicological Sciences

Volumn 36, Issue 1, 2011, Pages 109-116

  Imaizumi, Kazuhiko ^a   Sato, Shogo ^a,b   Kumazawa, Mari ^a   Arai, Natsuko ^a   Aritoshi, Shoko ^a   Akimoto, Shunta ^a   Sakakibara, Yuko ^a   Kawashima, Yu ^c   Tachiyashiki, Kaoru ^d  

^a WASEDA UNIVERSITY   (Japan)

^b JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

^c UNIVERSITY OF YAMANASHI   (Japan)

^d JOETSU UNIVERSITY OF EDUCATION   (Japan)

Author keywords

Capsaicin; Capsaicinoids; Dihydrocapsaicin; Plasama glucose; Plasma FFA; Plasma glycerol

Indexed keywords

CAPSAICIN; DIHYDROCAPSAICIN; FATTY ACID; GLUCOSE; GLYCEROL;

ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; DRUG EFFECT; FATTY ACID BLOOD LEVEL; FRUIT; GLUCOSE BLOOD LEVEL; GLYCEROL BLOOD LEVEL; LIPID METABOLISM; MALE; NONHUMAN; RAT; WHITE ADIPOSE TISSUE;

CAPSICUM ANNUUM VAR. ANNUUM; RATTUS;

EID: 79551601712     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.36.109     Document Type: Article

References (23)

1. Akimoto, S., Tanihata, J., Kawano, F., Sato, S., Takei, Y., Shirato, K., Someya, Y., Nomura, S., Tachiyashiki, K. and Imaizumi, K. (2009): Acute effects of dihydrocapsaicin and capsaicin on the distribution of white blood cells in rats. J. Nutr. Sci. Vitaminol., 55, 282-287.
2. Aritoshi, S., Sato, S., Kumazawa, M., Ban, T., Tanihata, J., Tachiyashiki, K. and Imaizumi, K. (2010): Subacute effects of capsaicinoids on the distribution of white blood cells in rats. J. Health Sci., 56, 99-103.
3. Cannon, B. and Nedergaard, J. (2004): Brown adipose tissue : function and physiological significance. Physiol. Rev., 84, 277-359.
4. Gamse, R., Molnar, A. and Lembeck, F. (1979): Substance P released from spinal cord slices by capsaicin. Life Sci., 25, 629-636.
5. Govindarajan, V.S. and Sathyanarayana, M.N. (1991): Capsicum production, technology, chemistry, and quality. Part V. Impact on physiology, pharmacology, nutrition, and metabolism; structure, pungency, pain and desensitization sequences. Crit. Rev. Food Sci. Nutr., 29, 435-474.
6. Imaizumi, K., Sakakibara, Y., Sasaki, H., Sato, S., Takei, Y., Hiruma, K., Ban, T., Kawashima, Y, Tanihata, J. and Tachiyashiki, K. (2010a): Lowering effects of allyl isothiocyanate on the number of lymphocyte and its subsets in rats. J. Health Sci., 56, 347-354.
7. Imaizumi, K., Sato, S., Sakakibara, Y, Mori, S., Ohkuma, M., Kawashima, Y., Ban, T., Sasaki, H. and Tachiyashiki, K. (2010b): Allyl isothiocyanate- induced changes in the distribution on white blood cellls in rats. J. Toxicol. Sci., 35, 583-589.
8. Kawabata, F., Inoue, N., Yazawa, S., Kawada, T., Inoue, K. and Fushiki, T. (2006): Effects of CH-19 sweet, a non-pungent cultivar of red pepper in decreasing the body weight and suppressing body fat accumulation by sympathetic nerve activation in humans. Biosci. Biotechnol. Biochem., 70, 2824-2835.
9. Kawashima, Y., Someya, Y., Sato, S., Shirato, K., Jinde, M., Ishida, S., Akimoto, S., Kobayashi, K., Sakakibara, Y., Suzuki, Y., Tachiyashiki, K. and Imaizumi, K. (2011): Dietary zinc-deficiency and its recovery responses in rat liver cytosolic alcohol dehydrogenase activities. J. Toxicol. Sci., in press.
10. Kim, K.M., Kawada, T., Ishihara, K., Inoue, K. and Fushiki, T. (1997): Increase in swimming endurance capacity of mice by capsaicin-induced adrenal catecholamine secretion. Biosci. Biotechnol. Biochem., 61, 1718-1723.
11. Kobata, K., Iwasawa, T., Iwasaki, Y., Morita, A., Suzuki, Y., Kikuzaki, H, Nakatani, N. and Watanabe, T. (2006): Capsaicinol: synthesis by allylic oxidation and its effect on TRPV1- expressing cells and adrenaline secretion in rats. Biosci. Bioctechnol. Biochem., 70, 1904-1912.
12. Nomura, S., Ichinose, T., Jinde, M., Kawashima, Y., Tachiyashiki, K. and Imaizumi, K. (2008): Tea catechins enhance the mRNA expression of uncoupling protein 1 in rat brown adipose tissue. J. Nutr. Biochem., 19, 840-847.
13. Ohkaru, Y., Arai, N., Ohno, H., Sato, S., Sakakibara, Y., Suzuki, H., Aritoshi, S., Akimoto, S., Ban, T., Tanihata, J., Tachiyashiki, K. And Imaizumi, K. (2010): Acute and subacute effects of dexamethasone on the number of white blood cells in rats. J. Health Sci., 56, 215-220.
14. Shirato, K., Motohashi, N., Tanihata, J., Tachiyashiki, K., Tomoda, A. and Imaizumi, K. (2006): Effect of two types of inactivity on the number of white blood cells in rats. Eur. J. Appl. Physiol., 98, 590-600.
15. 2-agonist clenbuterol induced changes in the distribution of white blood cells in rats. J. Pharmacol. Sci., 104, 146-152.
16. Someya, Y., Tanihata, J., Sato, S., Kawano, F., Shirato, K., Sugiyama, M., Kawashima, Y., Nomura, S., Tachiyashiki, K. and Imaizumi, K. (2009): Zinc-deficiency induced changes in the distribution of rat white blood cells. J. Nutr. Sci. Vitaminol., 55, 162-169.
17. Surh, Y.J. and Lee, S.S. (1995): Capsaicin, a double-edged sword : toxicity, metabolism, and chemopreventive potential. Life. Sci., 56, 1845-1855.
18. The Physiological Society of Japan (2004): Guiding principles for the care and use of animals in the field of physiological sciences. J. Physiol. Soc. Jpn., 54, 98.
19. Tominaga, M., Caterina, M.J., Malmberg, A.B., Rosen, T.A., Gilbert, H., Skinner, K., Raumann, B.E., Basbaum, A.I. and Julius, D. (1998): The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron, 21, 531-543. (Pubitemid 28475505)
20. Watanabe, T., Kawada, T., Yamamoto, M. and Iwai, K. (1987): Capsaicin, a pungent principle of hot red pepper, evokes catecholamine secretion from the adrenal medulla of anesthetized rats. Biochem. Biophys. Res. Commun., 142, 259-264.
21. Watanabe, T., Kawada, T., Kurosawa, M., Sato, A. and Iwai, K. (1988): Adrenal sympathetic efferent nerve and catecholamine secretion excitation caused by capsaicin in rats. Am. J. Physiol., 255, E23-E27.
22. Watanabe, T., Kawada, T., Kato, T., Harada, T. and Iwai, K. (1994) : Effects of capsaicin analogs on adrenal catecholamine secretion in rats. Life Sci., 54, 369-374. (Pubitemid 24049597)
23. Watanabe, T., Sakurada, N. and Kobata, K. (2001) : Capsaicin-, resiniferatoxin-, and olvanil-induced adrenaline secretion in rats via the vanilloid receptor. Biosci. Biotechnol. Biochem., 65, 2443-2447.