Association of anxiolytic drugs diazepam and lorazepam, and the antiepileptic valproate, with heart defects-Effects on cardiomyocytes in micromass (MM) and embryonic stem cell culture

Reproductive Toxicology

Volumn 31, Issue 1, 2011, Pages 66-74

  Ahir, Bhavesh K ^a   Pratten, Margaret K ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Congenital heart malformations; Cytotoxicity; Diazepam (DZ); Embryonic chick heart micromass (MM) culture; Embryonic stem cell (ESC) culture; Lorazepam (LZ); Teratogenicity embryotoxicity

Indexed keywords

DIAZEPAM; LORAZEPAM; PENICILLIN G; VALPROIC ACID;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL STRUCTURE; CELL VIABILITY; CHICK EMBRYO; CONCENTRATION RESPONSE; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; EMBRYONIC STEM CELL; HEART MUSCLE CELL; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; NONHUMAN; TERATOGENICITY;

ANIMALS; ANTI-ANXIETY AGENTS; CELL LINE; CELL SURVIVAL; CHICK EMBRYO; CHICKENS; DIAZEPAM; EMBRYO, MAMMALIAN; EMBRYONIC STEM CELLS; HEART RATE; LORAZEPAM; MICE; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PROTEINS; VALPROIC ACID;

EID: 79551601455     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2010.09.008     Document Type: Article

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