메뉴 건너뛰기




Volumn 40, Issue 2, 2011, Pages 126-137

Clinical usefulness of circulating ECD/HER-2 measurement for breast cancer patients' management;Doit-on doser le marqueur circulant ECD/HER-2 chez les patientes atteintes d'un cancer mammaire ?

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 2 EXTRACELLULAR DOMAIN; TRASTUZUMAB; UNCLASSIFIED DRUG;

EID: 79551564820     PISSN: 07554982     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lpm.2010.10.004     Document Type: Article
Times cited : (5)

References (103)
  • 2
    • 33847147313 scopus 로고    scopus 로고
    • American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
    • Wolff A.C., Hammond M.E., Schwartz J.N., Hagerty K.L., Allred D.C., Cote R.J., et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Oncol 2007, 25:118-145.
    • (2007) J Clin Oncol , vol.25 , pp. 118-145
    • Wolff, A.C.1    Hammond, M.E.2    Schwartz, J.N.3    Hagerty, K.L.4    Allred, D.C.5    Cote, R.J.6
  • 3
    • 0022399581 scopus 로고
    • Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
    • Coussens L., Yang-Feng T.L., Liao Y.C., Chen E., Gray A., McGrath J., et al. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science 1985, 230:1132-1139.
    • (1985) Science , vol.230 , pp. 1132-1139
    • Coussens, L.1    Yang-Feng, T.L.2    Liao, Y.C.3    Chen, E.4    Gray, A.5    McGrath, J.6
  • 4
    • 0022388402 scopus 로고
    • The neu gene: an erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor
    • Schechter A.L., Hung M.C., Vaidyanathan L., Weinberg R.A., Yang-Feng T.L., Francke U., et al. The neu gene: an erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor. Science 1985, 229:976-978.
    • (1985) Science , vol.229 , pp. 976-978
    • Schechter, A.L.1    Hung, M.C.2    Vaidyanathan, L.3    Weinberg, R.A.4    Yang-Feng, T.L.5    Francke, U.6
  • 6
    • 25144453930 scopus 로고    scopus 로고
    • Determination of HER2 gene amplification by fluorescence in situ hybridization and concordance with the clinical trials immunohistochemical assay in women with metastatic breast cancer evaluated for treatment with trastuzumab
    • Dybdal N., Leiberman G., Anderson S., McCune B., Bajamonde A., Cohen R.L., et al. Determination of HER2 gene amplification by fluorescence in situ hybridization and concordance with the clinical trials immunohistochemical assay in women with metastatic breast cancer evaluated for treatment with trastuzumab. Breast Cancer Res Treat 2005, 93:3-11.
    • (2005) Breast Cancer Res Treat , vol.93 , pp. 3-11
    • Dybdal, N.1    Leiberman, G.2    Anderson, S.3    McCune, B.4    Bajamonde, A.5    Cohen, R.L.6
  • 7
    • 37049183697 scopus 로고
    • Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon D.J., Clark G.M., Wong S.G., Levin W.J., Ullrich A., McGuire W.L. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987, 235:177-182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 8
    • 0032895235 scopus 로고    scopus 로고
    • Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer
    • Goldenberg M.M. Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer. Clin Ther 1999, 21:309-318.
    • (1999) Clin Ther , vol.21 , pp. 309-318
    • Goldenberg, M.M.1
  • 10
    • 3142765936 scopus 로고    scopus 로고
    • Infiltrating lobular carcinoma of the breast: tumor characteristics and clinical outcome. Breast Cancer Res
    • Arpino G, Bardou VJ, Clark GM, Elledge RM. Infiltrating lobular carcinoma of the breast: tumor characteristics and clinical outcome. Breast Cancer Res 2004;6:R149-56.
    • (2004) , vol.6
    • Arpino, G.1    Bardou, V.J.2    Clark, G.M.3    Elledge, R.M.4
  • 11
    • 58149237085 scopus 로고    scopus 로고
    • HER-2/neu expression in primary and metastatic breast cancer
    • Lower E.E., Glass E., Blau R., Harman S. HER-2/neu expression in primary and metastatic breast cancer. Breast Cancer Res Treat 2009, 113:301-306.
    • (2009) Breast Cancer Res Treat , vol.113 , pp. 301-306
    • Lower, E.E.1    Glass, E.2    Blau, R.3    Harman, S.4
  • 12
    • 17644393853 scopus 로고    scopus 로고
    • Comparison of HER-2 status determined by fluorescence in situ hybridization in primary and metastatic breast carcinoma
    • Gong Y., Booser D.J., Sneige N. Comparison of HER-2 status determined by fluorescence in situ hybridization in primary and metastatic breast carcinoma. Cancer 2005, 103:1763-1769.
    • (2005) Cancer , vol.103 , pp. 1763-1769
    • Gong, Y.1    Booser, D.J.2    Sneige, N.3
  • 13
    • 0033559210 scopus 로고    scopus 로고
    • Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells
    • Codony-Servat J., Albanell J., Lopez-Talavera J.C., Arribas J., Baselga J. Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells. Cancer Res 1999, 59:1196-1201.
    • (1999) Cancer Res , vol.59 , pp. 1196-1201
    • Codony-Servat, J.1    Albanell, J.2    Lopez-Talavera, J.C.3    Arribas, J.4    Baselga, J.5
  • 14
    • 0038796897 scopus 로고    scopus 로고
    • Serum HER-2/neu in the management of breast cancer patients
    • Luftner D., Luke C., Possinger K. Serum HER-2/neu in the management of breast cancer patients. Clin Biochem 2003, 36:233-240.
    • (2003) Clin Biochem , vol.36 , pp. 233-240
    • Luftner, D.1    Luke, C.2    Possinger, K.3
  • 15
    • 0025045873 scopus 로고
    • ELISA for quantitation of the extracellular domain of p185HER2 in biological fluids
    • Sias P.E., Kotts C.E., Vetterlein D., Shepard M., Wong W.L. ELISA for quantitation of the extracellular domain of p185HER2 in biological fluids. J Immunol Methods 1990, 132:73-80.
    • (1990) J Immunol Methods , vol.132 , pp. 73-80
    • Sias, P.E.1    Kotts, C.E.2    Vetterlein, D.3    Shepard, M.4    Wong, W.L.5
  • 16
    • 3142769775 scopus 로고    scopus 로고
    • Prognostic and predictive impact of the HER-2/neu extracellular domain (ECD) in the serum of patients treated with chemotherapy for metastatic breast cancer
    • Muller V., Witzel I., Luck H.J., Kohler G., von Minckwitz G., Mobus V., et al. Prognostic and predictive impact of the HER-2/neu extracellular domain (ECD) in the serum of patients treated with chemotherapy for metastatic breast cancer. Breast Cancer Res Treat 2004, 86:9-18.
    • (2004) Breast Cancer Res Treat , vol.86 , pp. 9-18
    • Muller, V.1    Witzel, I.2    Luck, H.J.3    Kohler, G.4    von Minckwitz, G.5    Mobus, V.6
  • 17
    • 0034816168 scopus 로고    scopus 로고
    • The prognostic and predictive values of ECD-HER-2
    • Hait W.N. The prognostic and predictive values of ECD-HER-2. Clin Cancer Res 2001, 7:2601-2604.
    • (2001) Clin Cancer Res , vol.7 , pp. 2601-2604
    • Hait, W.N.1
  • 18
    • 61449122308 scopus 로고    scopus 로고
    • Changes over time of extracellular domain of HER2 (ECD/HER2) serum levels have prognostic value in metastatic breast cancer
    • Bramwell V.H., Doig G.S., Tuck A.B., Wilson S.M., Tonkin K.S., Tomiak A., et al. Changes over time of extracellular domain of HER2 (ECD/HER2) serum levels have prognostic value in metastatic breast cancer. Breast Cancer Res Treat 2009, 114:503-511.
    • (2009) Breast Cancer Res Treat , vol.114 , pp. 503-511
    • Bramwell, V.H.1    Doig, G.S.2    Tuck, A.B.3    Wilson, S.M.4    Tonkin, K.S.5    Tomiak, A.6
  • 19
    • 3242688126 scopus 로고    scopus 로고
    • Prognostic significance of serum HER2 and CA 15-3 at the time of diagnosis of metastatic breast cancer
    • Fehm T., Jager W., Kramer S., Sohn C., Solomayer E., Wallwiener D., et al. Prognostic significance of serum HER2 and CA 15-3 at the time of diagnosis of metastatic breast cancer. Anticancer Res 2004, 24:1987-1992.
    • (2004) Anticancer Res , vol.24 , pp. 1987-1992
    • Fehm, T.1    Jager, W.2    Kramer, S.3    Sohn, C.4    Solomayer, E.5    Wallwiener, D.6
  • 20
    • 79551511227 scopus 로고    scopus 로고
    • Prognostic value of serum level of HER-2 extracellular domain (ECD) at diagnosis of HER-2 overexpressed primary breast cancer. ASCO Annual Meeting, J Clin Oncol ;abstr e11508.
    • Thureau S, Clatot F, Pillé J, Laberge-Le-Couteulx S, Rigal O, Veyret C, et al. Prognostic value of serum level of HER-2 extracellular domain (ECD) at diagnosis of HER-2 overexpressed primary breast cancer. ASCO Annual Meeting, J Clin Oncol 2009; 27(suppl);abstr e11508.
    • (2009) , vol.27 , Issue.SUPPL.
    • Thureau, S.1    Clatot, F.2    Pillé, J.3    Laberge-Le-Couteulx, S.4    Rigal, O.5    Veyret, C.6
  • 21
    • 61449122107 scopus 로고    scopus 로고
    • The prognostic and predictive values of circulating HER-2/neu extracellular domain in patients with metastatic breast cancer
    • Abu-Khalaf M.M., Harris L. The prognostic and predictive values of circulating HER-2/neu extracellular domain in patients with metastatic breast cancer. Breast Cancer Res Treat 2009, 114:513-515.
    • (2009) Breast Cancer Res Treat , vol.114 , pp. 513-515
    • Abu-Khalaf, M.M.1    Harris, L.2
  • 22
    • 0032532950 scopus 로고    scopus 로고
    • NH2-terminally truncated HER-2/neu protein: relationship with shedding of the extracellular domain and with prognostic factors in breast cancer
    • Christianson T.A., Doherty J.K., Lin Y.J., Ramsey E.E., Holmes R., Keenan E.J., et al. NH2-terminally truncated HER-2/neu protein: relationship with shedding of the extracellular domain and with prognostic factors in breast cancer. Cancer Res 1998, 58:5123-5129.
    • (1998) Cancer Res , vol.58 , pp. 5123-5129
    • Christianson, T.A.1    Doherty, J.K.2    Lin, Y.J.3    Ramsey, E.E.4    Holmes, R.5    Keenan, E.J.6
  • 23
    • 0034813368 scopus 로고    scopus 로고
    • Circulating HER-2/erbB-2/c-neu (HER-2) extracellular domain as a prognostic factor in patients with metastatic breast cancer: Cancer and Leukemia Group B Study 8662
    • Hayes D.F., Yamauchi H., Broadwater G., Cirrincione C.T., Rodrigue S.P., Berry D.A., et al. Circulating HER-2/erbB-2/c-neu (HER-2) extracellular domain as a prognostic factor in patients with metastatic breast cancer: Cancer and Leukemia Group B Study 8662. Clin Cancer Res 2001, 7:2703-2711.
    • (2001) Clin Cancer Res , vol.7 , pp. 2703-2711
    • Hayes, D.F.1    Yamauchi, H.2    Broadwater, G.3    Cirrincione, C.T.4    Rodrigue, S.P.5    Berry, D.A.6
  • 24
    • 0036345476 scopus 로고    scopus 로고
    • The HER2 extracellular domain as a prognostic and predictive factor in breast cancer
    • [discussion 136-137]
    • Nunes R.A., Harris L.N. The HER2 extracellular domain as a prognostic and predictive factor in breast cancer. Clin Breast Cancer 2002, 3:125-135. [discussion 136-137].
    • (2002) Clin Breast Cancer , vol.3 , pp. 125-135
    • Nunes, R.A.1    Harris, L.N.2
  • 25
    • 1842724749 scopus 로고    scopus 로고
    • Serum HER-2 extracellular domain: relationship with clinicobiological presentation and prognostic value before and after primary treatment in 701 breast cancer patients
    • Saghatchian M., Guepratte S., Hacene K., Neumann R., Floiras J.L., Pichon M.F. Serum HER-2 extracellular domain: relationship with clinicobiological presentation and prognostic value before and after primary treatment in 701 breast cancer patients. Int J Biol Markers 2004, 19.
    • (2004) Int J Biol Markers , vol.19
    • Saghatchian, M.1    Guepratte, S.2    Hacene, K.3    Neumann, R.4    Floiras, J.L.5    Pichon, M.F.6
  • 26
    • 16544376907 scopus 로고    scopus 로고
    • The course of serum HER-2/neu levels as an independent prognostic factor for survival in metastatic breast cancer
    • Schippinger W., Regitnig P., Bauernhofer T., Ploner F., Hofmann G., Krippl P., et al. The course of serum HER-2/neu levels as an independent prognostic factor for survival in metastatic breast cancer. Oncol Rep 2004, 11:1331-1336.
    • (2004) Oncol Rep , vol.11 , pp. 1331-1336
    • Schippinger, W.1    Regitnig, P.2    Bauernhofer, T.3    Ploner, F.4    Hofmann, G.5    Krippl, P.6
  • 27
    • 0030678593 scopus 로고    scopus 로고
    • The prognostic significance of c-erbB-2 serum protein in metastatic breast cancer
    • Fehm T., Maimonis P., Katalinic A., Jager W.H. The prognostic significance of c-erbB-2 serum protein in metastatic breast cancer. Oncology 1998, 55:33-38.
    • (1998) Oncology , vol.55 , pp. 33-38
    • Fehm, T.1    Maimonis, P.2    Katalinic, A.3    Jager, W.H.4
  • 28
    • 0031048153 scopus 로고    scopus 로고
    • Influence of circulating c-erbB-2 serum protein on response to adjuvant chemotherapy in node-positive breast cancer patients
    • Fehm T., Maimonis P., Weitz S., Teramoto Y., Katalinic A., Jager W. Influence of circulating c-erbB-2 serum protein on response to adjuvant chemotherapy in node-positive breast cancer patients. Breast Cancer Res Treat 1997, 43:87-95.
    • (1997) Breast Cancer Res Treat , vol.43 , pp. 87-95
    • Fehm, T.1    Maimonis, P.2    Weitz, S.3    Teramoto, Y.4    Katalinic, A.5    Jager, W.6
  • 30
    • 43049106865 scopus 로고    scopus 로고
    • Evaluation of serum HER2 extracellular domain in early breast cancer patients: correlation with clinicopathological parameters and survival
    • Ludovini V., Gori S., Colozza M., Pistola L., Rulli E., Floriani I., et al. Evaluation of serum HER2 extracellular domain in early breast cancer patients: correlation with clinicopathological parameters and survival. Ann Oncol 2008, 19:883-890.
    • (2008) Ann Oncol , vol.19 , pp. 883-890
    • Ludovini, V.1    Gori, S.2    Colozza, M.3    Pistola, L.4    Rulli, E.5    Floriani, I.6
  • 31
    • 33749534006 scopus 로고    scopus 로고
    • C-erbB-2 protein level in tissue and sera of breast cancer patients: a possibly useful clinical correlation
    • Quaranta M., Daniele A., Coviello M., Savonarola A., Abbate I., Venneri M.T., et al. c-erbB-2 protein level in tissue and sera of breast cancer patients: a possibly useful clinical correlation. Tumori 2006, 92:311-317.
    • (2006) Tumori , vol.92 , pp. 311-317
    • Quaranta, M.1    Daniele, A.2    Coviello, M.3    Savonarola, A.4    Abbate, I.5    Venneri, M.T.6
  • 32
    • 7844249246 scopus 로고    scopus 로고
    • C-erbB-2 oncoprotein CEA, and CA 15. 3 in patients with breast cancer: prognostic value
    • Molina R., Jo J., Filella X., Zanon G., Pahisa J., Munoz M., et al. c-erbB-2 oncoprotein CEA, and CA 15. 3 in patients with breast cancer: prognostic value. Breast Cancer Res Treat 1998, 51:109-119.
    • (1998) Breast Cancer Res Treat , vol.51 , pp. 109-119
    • Molina, R.1    Jo, J.2    Filella, X.3    Zanon, G.4    Pahisa, J.5    Munoz, M.6
  • 33
    • 0038199627 scopus 로고    scopus 로고
    • Prospective evaluation of tumor markers (c-erbB-2 oncoprotein CEA and CA 15. 3) in patients with locoregional breast cancer
    • Molina R., Filella X., Zanon G., Pahisa J., Alicarte J., Munoz M., et al. Prospective evaluation of tumor markers (c-erbB-2 oncoprotein CEA and CA 15. 3) in patients with locoregional breast cancer. Anticancer Res 2003, 23:1043-1050.
    • (2003) Anticancer Res , vol.23 , pp. 1043-1050
    • Molina, R.1    Filella, X.2    Zanon, G.3    Pahisa, J.4    Alicarte, J.5    Munoz, M.6
  • 34
    • 0031804617 scopus 로고    scopus 로고
    • Plasma c-erbB-2 levels in breast cancer patients: prognostic significance in predicting response to chemotherapy
    • Mehta R.R., McDermott J.H., Hieken T.J., Marler K.C., Patel M.K., Wild L.D., et al. Plasma c-erbB-2 levels in breast cancer patients: prognostic significance in predicting response to chemotherapy. J Clin Oncol 1998, 16:2409-2416.
    • (1998) J Clin Oncol , vol.16 , pp. 2409-2416
    • Mehta, R.R.1    McDermott, J.H.2    Hieken, T.J.3    Marler, K.C.4    Patel, M.K.5    Wild, L.D.6
  • 35
    • 79551516255 scopus 로고    scopus 로고
    • Serum HER2 (sHER2) levels in early-stage HER2 neu (+) breast cancer (HER2+BC): results from the NCCTG adjuvant Intergroup trial N9831. ASCO Annual Meeting, J Clin Oncol [Abstract]
    • Moreno-Aspitia A, Hillman D, Dueck A, Carney W, Lingle W, Tenner K, et al. Serum HER2 (sHER2) levels in early-stage HER2 neu (+) breast cancer (HER2+BC): results from the NCCTG adjuvant Intergroup trial N9831. ASCO Annual Meeting, J Clin Oncol 2008 [Abstract] 26:A-529.
    • (2008) , vol.26
    • Moreno-Aspitia, A.1    Hillman, D.2    Dueck, A.3    Carney, W.4    Lingle, W.5    Tenner, K.6
  • 36
    • 43549092061 scopus 로고    scopus 로고
    • Trastuzumab plus paclitaxel or docetaxel in HER-2-negative/HER-2 ECD-positive anthracycline- and taxane-refractory advanced breast cancer
    • Ardavanis A., Kountourakis P., Kyriakou F., Malliou S., Mantzaris I., Garoufali A., et al. Trastuzumab plus paclitaxel or docetaxel in HER-2-negative/HER-2 ECD-positive anthracycline- and taxane-refractory advanced breast cancer. Oncologist 2008, 13:361-369.
    • (2008) Oncologist , vol.13 , pp. 361-369
    • Ardavanis, A.1    Kountourakis, P.2    Kyriakou, F.3    Malliou, S.4    Mantzaris, I.5    Garoufali, A.6
  • 37
    • 33745802997 scopus 로고    scopus 로고
    • Selective inhibition of ADAM metalloproteases blocks HER-2 extracellular domain (ECD) cleavage and potentiates the anti-tumor effects of trastuzumab
    • Liu X., Fridman J.S., Wang Q., Caulder E., Yang G., Covington M., et al. Selective inhibition of ADAM metalloproteases blocks HER-2 extracellular domain (ECD) cleavage and potentiates the anti-tumor effects of trastuzumab. Cancer Biol Ther 2006, 5:648-656.
    • (2006) Cancer Biol Ther , vol.5 , pp. 648-656
    • Liu, X.1    Fridman, J.S.2    Wang, Q.3    Caulder, E.4    Yang, G.5    Covington, M.6
  • 38
    • 67650073219 scopus 로고    scopus 로고
    • Kinetics of HER2/neu ECD in 45 patients treated with Trastuzumab (Herceptin(R)) between January 2001 and June 2005 at the Grenoble University Hospital
    • Gauchez A.S., Colonna M., Brand F.X., Ravanel N., Pasquier D., Payan R., et al. Kinetics of HER2/neu ECD in 45 patients treated with Trastuzumab (Herceptin(R)) between January 2001 and June 2005 at the Grenoble University Hospital. Anticancer Res 2009, 29:1703-1707.
    • (2009) Anticancer Res , vol.29 , pp. 1703-1707
    • Gauchez, A.S.1    Colonna, M.2    Brand, F.X.3    Ravanel, N.4    Pasquier, D.5    Payan, R.6
  • 39
    • 43549124806 scopus 로고    scopus 로고
    • Commentary: can circulating HER-2 extracellular domain predict response to trastuzumab in HER-2-negative breast cancer?
    • Esteva F.J. Commentary: can circulating HER-2 extracellular domain predict response to trastuzumab in HER-2-negative breast cancer?. Oncologist 2008, 13:370-372.
    • (2008) Oncologist , vol.13 , pp. 370-372
    • Esteva, F.J.1
  • 40
    • 14644401104 scopus 로고    scopus 로고
    • Serum HER2 extracellular domain in metastatic breast cancer patients treated with weekly trastuzumab and paclitaxel: association with HER2 status by immunohistochemistry and fluorescence in situ hybridization and with response rate
    • Fornier M.N., Seidman A.D., Schwartz M.K., Ghani F., Thiel R., Norton L., et al. Serum HER2 extracellular domain in metastatic breast cancer patients treated with weekly trastuzumab and paclitaxel: association with HER2 status by immunohistochemistry and fluorescence in situ hybridization and with response rate. Ann Oncol 2005, 16:234-239.
    • (2005) Ann Oncol , vol.16 , pp. 234-239
    • Fornier, M.N.1    Seidman, A.D.2    Schwartz, M.K.3    Ghani, F.4    Thiel, R.5    Norton, L.6
  • 41
    • 63749132329 scopus 로고    scopus 로고
    • Utility of serum HER2 extracellular domain assessment in clinical decision making: pooled analysis of four trials of trastuzumab in metastatic breast cancer
    • Lennon S., Barton C., Banken L., Gianni L., Marty M., Baselga J., et al. Utility of serum HER2 extracellular domain assessment in clinical decision making: pooled analysis of four trials of trastuzumab in metastatic breast cancer. J Clin Oncol 2009, 27:1685-1693.
    • (2009) J Clin Oncol , vol.27 , pp. 1685-1693
    • Lennon, S.1    Barton, C.2    Banken, L.3    Gianni, L.4    Marty, M.5    Baselga, J.6
  • 42
    • 17144371333 scopus 로고    scopus 로고
    • Phase II study of efficacy, safety, and pharmacokinetics of trastuzumab monotherapy administered on a 3-weekly schedule
    • Baselga J., Carbonell X., Castaneda-Soto N.J., Clemens M., Green M., Harvey V., et al. Phase II study of efficacy, safety, and pharmacokinetics of trastuzumab monotherapy administered on a 3-weekly schedule. J Clin Oncol 2005, 23:2162-2171.
    • (2005) J Clin Oncol , vol.23 , pp. 2162-2171
    • Baselga, J.1    Carbonell, X.2    Castaneda-Soto, N.J.3    Clemens, M.4    Green, M.5    Harvey, V.6
  • 43
    • 33846677976 scopus 로고    scopus 로고
    • Kinetics of serum HER-2/neu changes in patients with HER-2-positive primary breast cancer after initiation of primary chemotherapy
    • Mazouni C., Hall A., Broglio K., Fritsche H., Andre F., Esteva F.J., et al. Kinetics of serum HER-2/neu changes in patients with HER-2-positive primary breast cancer after initiation of primary chemotherapy. Cancer 2007, 109:496-501.
    • (2007) Cancer , vol.109 , pp. 496-501
    • Mazouni, C.1    Hall, A.2    Broglio, K.3    Fritsche, H.4    Andre, F.5    Esteva, F.J.6
  • 44
    • 33644528230 scopus 로고    scopus 로고
    • Clinical utility of serum HER2/neu in monitoring and prediction of progression-free survival in metastatic breast cancer patients treated with trastuzumab-based therapies. Breast Cancer Res
    • Esteva FJ, Cheli CD, Fritsche H, Fornier M, Slamon D, Thiel RP, et al. Clinical utility of serum HER2/neu in monitoring and prediction of progression-free survival in metastatic breast cancer patients treated with trastuzumab-based therapies. Breast Cancer 2005;Res 7:R436-43.
    • (2005) , vol.7
    • Esteva, F.J.1    Cheli, C.D.2    Fritsche, H.3    Fornier, M.4    Slamon, D.5    Thiel, R.P.6
  • 45
    • 28444491796 scopus 로고    scopus 로고
    • Gefitinib (ZD1839) combined with weekly epirubicin in patients with metastatic breast cancer: a phase I study with biological correlate
    • Gasparini G., Sarmiento R., Amici S., Longo R., Gattuso D., Zancan M., et al. Gefitinib (ZD1839) combined with weekly epirubicin in patients with metastatic breast cancer: a phase I study with biological correlate. Ann Oncol 2005, 16:1867-1873.
    • (2005) Ann Oncol , vol.16 , pp. 1867-1873
    • Gasparini, G.1    Sarmiento, R.2    Amici, S.3    Longo, R.4    Gattuso, D.5    Zancan, M.6
  • 46
    • 0041885349 scopus 로고    scopus 로고
    • Trastuzumab and vinorelbine as first-line therapy for HER2-overexpressing metastatic breast cancer: multicenter phase II trial with clinical outcomes, analysis of serum tumor markers as predictive factors, and cardiac surveillance algorithm
    • Burstein H.J., Harris L.N., Marcom P.K., Lambert-Falls R., Havlin K., Overmoyer B., et al. Trastuzumab and vinorelbine as first-line therapy for HER2-overexpressing metastatic breast cancer: multicenter phase II trial with clinical outcomes, analysis of serum tumor markers as predictive factors, and cardiac surveillance algorithm. J Clin Oncol 2003, 21:2889-2895.
    • (2003) J Clin Oncol , vol.21 , pp. 2889-2895
    • Burstein, H.J.1    Harris, L.N.2    Marcom, P.K.3    Lambert-Falls, R.4    Havlin, K.5    Overmoyer, B.6
  • 47
    • 0036534121 scopus 로고    scopus 로고
    • Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer
    • Esteva F.J., Valero V., Booser D., Guerra L.T., Murray J.L., Pusztai L., et al. Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer. J Clin Oncol 2002, 20:1800-1808.
    • (2002) J Clin Oncol , vol.20 , pp. 1800-1808
    • Esteva, F.J.1    Valero, V.2    Booser, D.3    Guerra, L.T.4    Murray, J.L.5    Pusztai, L.6
  • 48
    • 3543146052 scopus 로고    scopus 로고
    • Monitoring of serum Her-2/neu predicts response and progression-free survival to trastuzumab-based treatment in patients with metastatic breast cancer
    • Kostler W.J., Schwab B., Singer C.F., Neumann R., Rucklinger E., Brodowicz T., et al. Monitoring of serum Her-2/neu predicts response and progression-free survival to trastuzumab-based treatment in patients with metastatic breast cancer. Clin Cancer Res 2004, 10:1618-1624.
    • (2004) Clin Cancer Res , vol.10 , pp. 1618-1624
    • Kostler, W.J.1    Schwab, B.2    Singer, C.F.3    Neumann, R.4    Rucklinger, E.5    Brodowicz, T.6
  • 49
    • 2442613063 scopus 로고    scopus 로고
    • Monitoring of serum Her-2/neu predicts histopathological response to neoadjuvant trastuzumab-based therapy for breast cancer
    • Kostler W.J., Steger G.G., Soleiman A., Schwab B., Singer C.F., Tomek S., et al. Monitoring of serum Her-2/neu predicts histopathological response to neoadjuvant trastuzumab-based therapy for breast cancer. Anticancer Res 2004, 24:1127-1130.
    • (2004) Anticancer Res , vol.24 , pp. 1127-1130
    • Kostler, W.J.1    Steger, G.G.2    Soleiman, A.3    Schwab, B.4    Singer, C.F.5    Tomek, S.6
  • 50
    • 0141615794 scopus 로고    scopus 로고
    • Potential clinical utility of serum HER-2/neu oncoprotein concentrations in patients with breast cancer
    • Carney W.P., Neumann R., Lipton A., Leitzel K., Ali S., Price C.P. Potential clinical utility of serum HER-2/neu oncoprotein concentrations in patients with breast cancer. Clin Chem 2003, 49:1579-1598.
    • (2003) Clin Chem , vol.49 , pp. 1579-1598
    • Carney, W.P.1    Neumann, R.2    Lipton, A.3    Leitzel, K.4    Ali, S.5    Price, C.P.6
  • 51
    • 34447302323 scopus 로고    scopus 로고
    • Circulating HER2 mRNA-positive cells in the peripheral blood of patients with stage I and II breast cancer after the administration of adjuvant chemotherapy: evaluation of their clinical relevance
    • Apostolaki S., Perraki M., Pallis A., Bozionelou V., Agelaki S., Kanellou P., et al. Circulating HER2 mRNA-positive cells in the peripheral blood of patients with stage I and II breast cancer after the administration of adjuvant chemotherapy: evaluation of their clinical relevance. Ann Oncol 2007, 18:851-858.
    • (2007) Ann Oncol , vol.18 , pp. 851-858
    • Apostolaki, S.1    Perraki, M.2    Pallis, A.3    Bozionelou, V.4    Agelaki, S.5    Kanellou, P.6
  • 52
    • 0034082031 scopus 로고    scopus 로고
    • Circulating HER2 extracellular domain and resistance to chemotherapy in advanced breast cancer
    • Colomer R., Montero S., Lluch A., Ojeda B., Barnadas A., Casado A., et al. Circulating HER2 extracellular domain and resistance to chemotherapy in advanced breast cancer. Clin Cancer Res 2000, 6:2356-2362.
    • (2000) Clin Cancer Res , vol.6 , pp. 2356-2362
    • Colomer, R.1    Montero, S.2    Lluch, A.3    Ojeda, B.4    Barnadas, A.5    Casado, A.6
  • 53
    • 24744457132 scopus 로고    scopus 로고
    • Docetaxel plus epirubicin as first-line chemotherapy in MBC (KCSG 01-10-05): phase II trial and the predictive values of circulating HER2 extracellular domain and vascular endothelial growth factor
    • Im S.A., Kim S.B., Lee M.H., Im Y.H., Lee K.H., Song H.S., et al. Docetaxel plus epirubicin as first-line chemotherapy in MBC (KCSG 01-10-05): phase II trial and the predictive values of circulating HER2 extracellular domain and vascular endothelial growth factor. Oncol Rep 2005, 14:481-487.
    • (2005) Oncol Rep , vol.14 , pp. 481-487
    • Im, S.A.1    Kim, S.B.2    Lee, M.H.3    Im, Y.H.4    Lee, K.H.5    Song, H.S.6
  • 54
    • 35348813713 scopus 로고    scopus 로고
    • The predictive value of EGFR and HER-2/neu in tumor tissue and serum for response to anthracycline-based neoadjuvant chemotherapy of breast cancer
    • Schippinger W., Dandachi N., Regitnig P., Hofmann G., Balic M., Neumann R., et al. The predictive value of EGFR and HER-2/neu in tumor tissue and serum for response to anthracycline-based neoadjuvant chemotherapy of breast cancer. Am J Clin Pathol 2007, 128:630-637.
    • (2007) Am J Clin Pathol , vol.128 , pp. 630-637
    • Schippinger, W.1    Dandachi, N.2    Regitnig, P.3    Hofmann, G.4    Balic, M.5    Neumann, R.6
  • 55
    • 0035868650 scopus 로고    scopus 로고
    • Comparison of methods of measuring HER-2 in metastatic breast cancer patients treated with high-dose chemotherapy
    • Harris L.N., Liotcheva V., Broadwater G., Ramirez M.J., Maimonis P., Anderson S., et al. Comparison of methods of measuring HER-2 in metastatic breast cancer patients treated with high-dose chemotherapy. J Clin Oncol 2001, 19:1698-1706.
    • (2001) J Clin Oncol , vol.19 , pp. 1698-1706
    • Harris, L.N.1    Liotcheva, V.2    Broadwater, G.3    Ramirez, M.J.4    Maimonis, P.5    Anderson, S.6
  • 56
    • 0029920521 scopus 로고    scopus 로고
    • Plasma c-erbB2 concentrations in relation to chemotherapy in breast cancer patients
    • Revillion F., Hebbar M., Bonneterre J., Peyrat J.P. Plasma c-erbB2 concentrations in relation to chemotherapy in breast cancer patients. Eur J Cancer 1996, 32A:231-234.
    • (1996) Eur J Cancer , vol.32 , Issue.A , pp. 231-234
    • Revillion, F.1    Hebbar, M.2    Bonneterre, J.3    Peyrat, J.P.4
  • 57
    • 36048939321 scopus 로고    scopus 로고
    • High circulating HER2 extracellular domain levels correlate with reduced efficacy of an aromatase inhibitor in hormone receptor-positive metastatic breast cancer: a confirmatory prospective study
    • Colomer R., Llombart-Cussac A., Lloveras B., Ramos M., Mayordomo J.I., Fernandez R., et al. High circulating HER2 extracellular domain levels correlate with reduced efficacy of an aromatase inhibitor in hormone receptor-positive metastatic breast cancer: a confirmatory prospective study. Cancer 2007, 110:2178-2185.
    • (2007) Cancer , vol.110 , pp. 2178-2185
    • Colomer, R.1    Llombart-Cussac, A.2    Lloveras, B.3    Ramos, M.4    Mayordomo, J.I.5    Fernandez, R.6
  • 58
    • 0029005754 scopus 로고
    • Elevated serum c-erbB-2 antigen levels and decreased response to hormone therapy of breast cancer
    • Leitzel K., Teramoto Y., Konrad K., Chinchilli V.M., Volas G., Grossberg H., et al. Elevated serum c-erbB-2 antigen levels and decreased response to hormone therapy of breast cancer. J Clin Oncol 1995, 13:1129-1135.
    • (1995) J Clin Oncol , vol.13 , pp. 1129-1135
    • Leitzel, K.1    Teramoto, Y.2    Konrad, K.3    Chinchilli, V.M.4    Volas, G.5    Grossberg, H.6
  • 59
    • 22244446128 scopus 로고    scopus 로고
    • Serum HER-2/neu conversion to positive at the time of disease progression in patients with breast carcinoma on hormone therapy
    • Lipton A., Leitzel K., Ali S.M., Demers L., Harvey H.A., Chaudri-Ross H.A., et al. Serum HER-2/neu conversion to positive at the time of disease progression in patients with breast carcinoma on hormone therapy. Cancer 2005, 104:257-263.
    • (2005) Cancer , vol.104 , pp. 257-263
    • Lipton, A.1    Leitzel, K.2    Ali, S.M.3    Demers, L.4    Harvey, H.A.5    Chaudri-Ross, H.A.6
  • 60
    • 0038011944 scopus 로고    scopus 로고
    • Serum HER-2/neu and response to the aromatase inhibitor letrozole versus tamoxifen
    • Lipton A., Ali S.M., Leitzel K., Demers L., Harvey H.A., Chaudri-Ross H.A., et al. Serum HER-2/neu and response to the aromatase inhibitor letrozole versus tamoxifen. J Clin Oncol 2003, 21:1967-1972.
    • (2003) J Clin Oncol , vol.21 , pp. 1967-1972
    • Lipton, A.1    Ali, S.M.2    Leitzel, K.3    Demers, L.4    Harvey, H.A.5    Chaudri-Ross, H.A.6
  • 61
    • 0037087535 scopus 로고    scopus 로고
    • Elevated serum Her-2/neu level predicts decreased response to hormone therapy in metastatic breast cancer
    • Lipton A., Ali S.M., Leitzel K., Demers L., Chinchilli V., Engle L., et al. Elevated serum Her-2/neu level predicts decreased response to hormone therapy in metastatic breast cancer. J Clin Oncol 2002, 20:1467-1472.
    • (2002) J Clin Oncol , vol.20 , pp. 1467-1472
    • Lipton, A.1    Ali, S.M.2    Leitzel, K.3    Demers, L.4    Chinchilli, V.5    Engle, L.6
  • 62
    • 40449098857 scopus 로고    scopus 로고
    • Determination of HER2 status using both serum HER2 levels and circulating tumor cells in patients with recurrent breast cancer whose primary tumor was HER2 negative or of unknown HER2 status
    • Fehm T., Becker S., Duerr-Stoerzer S., Sotlar K., Mueller V., Wallwiener D., et al. Determination of HER2 status using both serum HER2 levels and circulating tumor cells in patients with recurrent breast cancer whose primary tumor was HER2 negative or of unknown HER2 status. Breast Cancer Res 2007, 9:R74.
    • (2007) Breast Cancer Res , vol.9
    • Fehm, T.1    Becker, S.2    Duerr-Stoerzer, S.3    Sotlar, K.4    Mueller, V.5    Wallwiener, D.6
  • 63
    • 19944386550 scopus 로고    scopus 로고
    • Comparison of pre- and postsurgical concentrations of blood HER-2 mRNA and HER-2 extracellular domain reflects HER-2 status in early breast cancer
    • Salvadori B., Pinzani P., Distante V., Casella D., Bianchi S., Paglierani M., et al. Comparison of pre- and postsurgical concentrations of blood HER-2 mRNA and HER-2 extracellular domain reflects HER-2 status in early breast cancer. Clin Chem 2005, 51:254-256.
    • (2005) Clin Chem , vol.51 , pp. 254-256
    • Salvadori, B.1    Pinzani, P.2    Distante, V.3    Casella, D.4    Bianchi, S.5    Paglierani, M.6
  • 64
    • 14944343559 scopus 로고    scopus 로고
    • Changes of serum HER2 status during clinical course of metastatic breast cancer patients
    • Fehm T., Jager W., Kraemer S., Sohn C., Solomayer-Meyberg G., Solomayer E.F., et al. Changes of serum HER2 status during clinical course of metastatic breast cancer patients. Anticancer Res 2004, 24:4205-4210.
    • (2004) Anticancer Res , vol.24 , pp. 4205-4210
    • Fehm, T.1    Jager, W.2    Kraemer, S.3    Sohn, C.4    Solomayer-Meyberg, G.5    Solomayer, E.F.6
  • 65
    • 40349093131 scopus 로고    scopus 로고
    • Serum epidermal growth factor receptor and HER2 expression in primary and metastatic breast cancer patients
    • R75
    • Asgeirsson K.S., Agrawal A., Allen C., Hitch A., Ellis I.O., Chapman C., et al. Serum epidermal growth factor receptor and HER2 expression in primary and metastatic breast cancer patients. Breast Cancer Res 2007, 9. R75.
    • (2007) Breast Cancer Res , vol.9
    • Asgeirsson, K.S.1    Agrawal, A.2    Allen, C.3    Hitch, A.4    Ellis, I.O.5    Chapman, C.6
  • 66
    • 33746589461 scopus 로고    scopus 로고
    • Predicting tissue HER2 status using serum HER2 levels in patients with metastatic breast cancer
    • Kong S.Y., Nam B.H., Lee K.S., Kwon Y., Lee E.S., Seong M.W., et al. Predicting tissue HER2 status using serum HER2 levels in patients with metastatic breast cancer. Clin Chem 2006, 52:1510-1515.
    • (2006) Clin Chem , vol.52 , pp. 1510-1515
    • Kong, S.Y.1    Nam, B.H.2    Lee, K.S.3    Kwon, Y.4    Lee, E.S.5    Seong, M.W.6
  • 67
    • 0028597482 scopus 로고
    • C-erb-B2 gene amplification and serum level of c-erb-B2 oncoprotein at primary breast cancer diagnosis
    • Fontana X., Ferrari P., Namer M., Peysson R., Salanon C., Bussiere F. C-erb-B2 gene amplification and serum level of c-erb-B2 oncoprotein at primary breast cancer diagnosis. Anticancer Res 1994, 14:2099-2104.
    • (1994) Anticancer Res , vol.14 , pp. 2099-2104
    • Fontana, X.1    Ferrari, P.2    Namer, M.3    Peysson, R.4    Salanon, C.5    Bussiere, F.6
  • 68
    • 0037524289 scopus 로고    scopus 로고
    • HER-2/neu determination in blood plasma of patients with HER-2/neu overexpressing metastasized breast cancer: a longitudinal study
    • Hoopmann M., Neumann R., Tanasale T., Schondorf T. HER-2/neu determination in blood plasma of patients with HER-2/neu overexpressing metastasized breast cancer: a longitudinal study. Anticancer Res 2003, 23:1031-1034.
    • (2003) Anticancer Res , vol.23 , pp. 1031-1034
    • Hoopmann, M.1    Neumann, R.2    Tanasale, T.3    Schondorf, T.4
  • 69
    • 2442432730 scopus 로고    scopus 로고
    • Longitudinal changes in serum HER-2/neu oncoprotein levels in trastuzumab-treated metastatic breast cancer patients
    • Bethune-Volters A., Labroquere M., Guepratte S., Hacene K., Neumann R., Carney W., et al. Longitudinal changes in serum HER-2/neu oncoprotein levels in trastuzumab-treated metastatic breast cancer patients. Anticancer Res 2004, 24:1083-1089.
    • (2004) Anticancer Res , vol.24 , pp. 1083-1089
    • Bethune-Volters, A.1    Labroquere, M.2    Guepratte, S.3    Hacene, K.4    Neumann, R.5    Carney, W.6
  • 70
    • 32144449276 scopus 로고    scopus 로고
    • HER-2/neu status of primary breast cancer and corresponding metastatic sites in patients with advanced breast cancer treated with trastuzumab-based therapy
    • Pectasides D., Gaglia A., Arapantoni-Dadioti P., Bobota A., Valavanis C., Kostopoulou V., et al. HER-2/neu status of primary breast cancer and corresponding metastatic sites in patients with advanced breast cancer treated with trastuzumab-based therapy. Anticancer Res 2006, 26:647-653.
    • (2006) Anticancer Res , vol.26 , pp. 647-653
    • Pectasides, D.1    Gaglia, A.2    Arapantoni-Dadioti, P.3    Bobota, A.4    Valavanis, C.5    Kostopoulou, V.6
  • 72
    • 0027939623 scopus 로고
    • Clinical evaluation of serum ErbB-2 protein using enzyme immuno assay (ErbB-2 EIA [Nichirei])
    • Sugano K., Kawai T., Ishii M., Koyama H., Kitajima M., Kasumi F., et al. Clinical evaluation of serum ErbB-2 protein using enzyme immuno assay (ErbB-2 EIA [Nichirei]). Gan To Kagaku Ryoho 1994, 21:1255-1262.
    • (1994) Gan To Kagaku Ryoho , vol.21 , pp. 1255-1262
    • Sugano, K.1    Kawai, T.2    Ishii, M.3    Koyama, H.4    Kitajima, M.5    Kasumi, F.6
  • 73
    • 0027267647 scopus 로고
    • The neu-oncogene product in serum and tissue of patients with breast carcinoma
    • Kath R., Hoffken K., Otte C., Metz K., Scheulen M.E., Hulskamp F., et al. The neu-oncogene product in serum and tissue of patients with breast carcinoma. Ann Oncol 1993, 4:585-590.
    • (1993) Ann Oncol , vol.4 , pp. 585-590
    • Kath, R.1    Hoffken, K.2    Otte, C.3    Metz, K.4    Scheulen, M.E.5    Hulskamp, F.6
  • 74
    • 0033842553 scopus 로고    scopus 로고
    • ErbB2 immune response in breast cancer patients with soluble receptor ectodomain
    • Visco V., Bei R., Moriconi E., Gianni W., Kraus M.H., Muraro R. ErbB2 immune response in breast cancer patients with soluble receptor ectodomain. Am J Pathol 2000, 156:1417-1424.
    • (2000) Am J Pathol , vol.156 , pp. 1417-1424
    • Visco, V.1    Bei, R.2    Moriconi, E.3    Gianni, W.4    Kraus, M.H.5    Muraro, R.6
  • 75
    • 0024348697 scopus 로고
    • Generation and characterization of monoclonal antibodies specific for the human neu oncogene product, p185
    • McKenzie S.J., Marks P.J., Lam T., Morgan J., Panicali D.L., Trimpe K.L., et al. Generation and characterization of monoclonal antibodies specific for the human neu oncogene product, p185. Oncogene 1989, 4:543-548.
    • (1989) Oncogene , vol.4 , pp. 543-548
    • McKenzie, S.J.1    Marks, P.J.2    Lam, T.3    Morgan, J.4    Panicali, D.L.5    Trimpe, K.L.6
  • 77
    • 0035000489 scopus 로고    scopus 로고
    • Clinical utility of serum HER-2/neu testing on the Bayer Immuno 1 automated system in breast cancer
    • Cook G.B., Neaman I.E., Goldblatt J.L., Cambetas D.R., Hussain M., Luftner D., et al. Clinical utility of serum HER-2/neu testing on the Bayer Immuno 1 automated system in breast cancer. Anticancer Res 2001, 21:1465-1470.
    • (2001) Anticancer Res , vol.21 , pp. 1465-1470
    • Cook, G.B.1    Neaman, I.E.2    Goldblatt, J.L.3    Cambetas, D.R.4    Hussain, M.5    Luftner, D.6
  • 79
    • 0034096263 scopus 로고    scopus 로고
    • The presence of soluble c-erbB-2 in saliva and serum among women with breast carcinoma: a preliminary study
    • Streckfus C., Bigler L., Dellinger T., Dai X., Kingman A., Thigpen J.T. The presence of soluble c-erbB-2 in saliva and serum among women with breast carcinoma: a preliminary study. Clin Cancer Res 2000, 6:2363-2370.
    • (2000) Clin Cancer Res , vol.6 , pp. 2363-2370
    • Streckfus, C.1    Bigler, L.2    Dellinger, T.3    Dai, X.4    Kingman, A.5    Thigpen, J.T.6
  • 80
  • 82
    • 0027979311 scopus 로고
    • Elevated erbB-2 oncoprotein levels in preoperative and follow-up serum samples define an aggressive disease course in patients with breast cancer
    • Isola J.J., Holli K., Oksa H., Teramoto Y., Kallioniemi O.P. Elevated erbB-2 oncoprotein levels in preoperative and follow-up serum samples define an aggressive disease course in patients with breast cancer. Cancer 1994, 73:652-658.
    • (1994) Cancer , vol.73 , pp. 652-658
    • Isola, J.J.1    Holli, K.2    Oksa, H.3    Teramoto, Y.4    Kallioniemi, O.P.5
  • 84
    • 0036713606 scopus 로고    scopus 로고
    • Clinical utility of serial serum c-erbB-2 determinations in the follow-up of breast cancer patients
    • Fehm T., Gebauer G., Jager W. Clinical utility of serial serum c-erbB-2 determinations in the follow-up of breast cancer patients. Breast Cancer Res Treat 2002, 75:97-106.
    • (2002) Breast Cancer Res Treat , vol.75 , pp. 97-106
    • Fehm, T.1    Gebauer, G.2    Jager, W.3
  • 85
    • 0034691610 scopus 로고    scopus 로고
    • Combined measurement of the c-erbB-2 protein in breast carcinoma tissues and sera is useful as a sensitive tumor marker for monitoring tumor relapse
    • Sugano K., Ushiama M., Fukutomi T., Tsuda H., Kitoh T., Ohkura H. Combined measurement of the c-erbB-2 protein in breast carcinoma tissues and sera is useful as a sensitive tumor marker for monitoring tumor relapse. Int J Cancer 2000, 89:329-336.
    • (2000) Int J Cancer , vol.89 , pp. 329-336
    • Sugano, K.1    Ushiama, M.2    Fukutomi, T.3    Tsuda, H.4    Kitoh, T.5    Ohkura, H.6
  • 86
    • 0035715619 scopus 로고    scopus 로고
    • Evaluation of HER-2/neu in serum and tissue of primary and metastatic breast cancer patients using an automated enzyme immunoassay
    • Dittadi R., Zancan M., Perasole A., Gion M. Evaluation of HER-2/neu in serum and tissue of primary and metastatic breast cancer patients using an automated enzyme immunoassay. Int J Biol Markers 2001, 16:255-261.
    • (2001) Int J Biol Markers , vol.16 , pp. 255-261
    • Dittadi, R.1    Zancan, M.2    Perasole, A.3    Gion, M.4
  • 87
    • 33845637765 scopus 로고    scopus 로고
    • Serum c-erbB-2 protein is a useful marker for monitoring tumor recurrence of the breast
    • Imoto S., Wada N., Hasebe T., Ochiai A., Kitoh T. Serum c-erbB-2 protein is a useful marker for monitoring tumor recurrence of the breast. Int J Cancer 2007, 120:357-361.
    • (2007) Int J Cancer , vol.120 , pp. 357-361
    • Imoto, S.1    Wada, N.2    Hasebe, T.3    Ochiai, A.4    Kitoh, T.5
  • 88
    • 79551521934 scopus 로고    scopus 로고
    • Baseline serum HER2 (sHER2) levels in the pivotal herceptin breast cancer trials: a comparison of 2 ELISA methods. Proc Am Soc Clin Oncol 77a.
    • Wong W, Bajamonde A, Nelson B, Carney W, Mass R. Baseline serum HER2 (sHER2) levels in the pivotal herceptin breast cancer trials: a comparison of 2 ELISA methods. Proc Am Soc Clin Oncol 2000;19:77a.
    • (2000) , vol.19
    • Wong, W.1    Bajamonde, A.2    Nelson, B.3    Carney, W.4    Mass, R.5
  • 89
    • 0031903646 scopus 로고    scopus 로고
    • Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment
    • Pegram M., Lipton A., Hayes D., Weber B., Baselga J., Tripathy D., et al. Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment. J Clin Oncol 1998, 1:2659-2671.
    • (1998) J Clin Oncol , vol.1 , pp. 2659-2671
    • Pegram, M.1    Lipton, A.2    Hayes, D.3    Weber, B.4    Baselga, J.5    Tripathy, D.6
  • 90
    • 79551505544 scopus 로고    scopus 로고
    • Effects of trastuzumab (H) and chemotherapy on circulating HER2 extracellular domain (ECD) in patients with metastatic breast cancer (MBC) and non-small cell lung cancer (NSCLC)
    • Leyland-Jones B., Marty M., Baselga J., Gatzemeier U., Barton C., Lennon S.L. Effects of trastuzumab (H) and chemotherapy on circulating HER2 extracellular domain (ECD) in patients with metastatic breast cancer (MBC) and non-small cell lung cancer (NSCLC). ASCO Meeting Abstracts 2004, 22:570.
    • (2004) ASCO Meeting Abstracts , vol.22 , pp. 570
    • Leyland-Jones, B.1    Marty, M.2    Baselga, J.3    Gatzemeier, U.4    Barton, C.5    Lennon, S.L.6
  • 91
    • 0030865749 scopus 로고    scopus 로고
    • Effects of interfering and influencing factors on the analyses of p105 (c-erbB-2/HER-2) oncoprotein fragment in serum
    • Mielke S., Meden H., Raab T., Wuttke W., Kuhn W. Effects of interfering and influencing factors on the analyses of p105 (c-erbB-2/HER-2) oncoprotein fragment in serum. Anticancer Res 1997, 17:3125-3127.
    • (1997) Anticancer Res , vol.17 , pp. 3125-3127
    • Mielke, S.1    Meden, H.2    Raab, T.3    Wuttke, W.4    Kuhn, W.5
  • 92
    • 0030852397 scopus 로고    scopus 로고
    • Hormonal treatment with sex steroids in women is associated with lower p105 serum concentrations
    • Meden H., Mielke S., Marx D., Wuttke W., Kuhn W. Hormonal treatment with sex steroids in women is associated with lower p105 serum concentrations. Anticancer Res 1997, 17:3075-3077.
    • (1997) Anticancer Res , vol.17 , pp. 3075-3077
    • Meden, H.1    Mielke, S.2    Marx, D.3    Wuttke, W.4    Kuhn, W.5
  • 93
    • 0030925133 scopus 로고    scopus 로고
    • Serum levels of C-erbB-2 (HER-2/neu) in patients with malignant and non-malignant diseases
    • Molina R., Jo J., Filella X., Bruix J., Castells A., Hague M., et al. Serum levels of C-erbB-2 (HER-2/neu) in patients with malignant and non-malignant diseases. Tumour Biol 1997, 18:188-196.
    • (1997) Tumour Biol , vol.18 , pp. 188-196
    • Molina, R.1    Jo, J.2    Filella, X.3    Bruix, J.4    Castells, A.5    Hague, M.6
  • 94
    • 1842737025 scopus 로고    scopus 로고
    • Serum HER-2 extracellular domain (ECD) before the first metastasis in 128 breast cancer patients
    • Pichon M.F., Hacene K., Guepratte S., Neumann R. Serum HER-2 extracellular domain (ECD) before the first metastasis in 128 breast cancer patients. Clin Lab 2004, 50:163-170.
    • (2004) Clin Lab , vol.50 , pp. 163-170
    • Pichon, M.F.1    Hacene, K.2    Guepratte, S.3    Neumann, R.4
  • 95
    • 25144458993 scopus 로고    scopus 로고
    • Breast Cancers Recommandations for clinical practice from Saint Paul de Vence. Oncologie
    • Breast Cancers Recommandations for clinical practice from Saint Paul de Vence. Oncologie 2005;7:342-79.
    • (2005) , vol.7 , pp. 342-79
  • 96
    • 37049024967 scopus 로고    scopus 로고
    • Breast Cancers Recommandations for clinical practice from Saint Paul de Vence
    • Oncologie 2007, 9:593-644. Breast Cancers Recommandations for clinical practice from Saint Paul de Vence.
    • (2007) Oncologie , vol.9 , pp. 593-644
  • 97
    • 0031564215 scopus 로고    scopus 로고
    • Soluble HER-2/neu neutralizes biologic effects of anti-HER-2/neu antibody on breast cancer cells in vitro
    • Brodowicz T., Wiltschke C., Budinsky A.C., Krainer M., Steger G.G., Zielinski C.C. Soluble HER-2/neu neutralizes biologic effects of anti-HER-2/neu antibody on breast cancer cells in vitro. Int J Cancer 1997, 73:875-879.
    • (1997) Int J Cancer , vol.73 , pp. 875-879
    • Brodowicz, T.1    Wiltschke, C.2    Budinsky, A.C.3    Krainer, M.4    Steger, G.G.5    Zielinski, C.C.6
  • 98
    • 34247588567 scopus 로고    scopus 로고
    • Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer
    • Scaltriti M., Rojo F., Ocana A., Anido J., Guzman M., Cortes J., et al. Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer. J Natl Cancer Inst 2007, 99:628-638.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 628-638
    • Scaltriti, M.1    Rojo, F.2    Ocana, A.3    Anido, J.4    Guzman, M.5    Cortes, J.6
  • 99
    • 0035874981 scopus 로고    scopus 로고
    • Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells
    • Molina M.A., Codony-Servat J., Albanell J., Rojo F., Arribas J., Baselga J. Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells. Cancer Res 2001, 61:4744-4749.
    • (2001) Cancer Res , vol.61 , pp. 4744-4749
    • Molina, M.A.1    Codony-Servat, J.2    Albanell, J.3    Rojo, F.4    Arribas, J.5    Baselga, J.6
  • 101
    • 10744226755 scopus 로고    scopus 로고
    • Biweekly paclitaxel plus gemcitabine in advanced breast cancer: phase II trial and predictive value of HER2 extracellular domain
    • Colomer R., Llombart-Cussac A., Lluch A., Barnadas A., Ojeda B., Caranana V., et al. Biweekly paclitaxel plus gemcitabine in advanced breast cancer: phase II trial and predictive value of HER2 extracellular domain. Ann Oncol 2004, 15:201-206.
    • (2004) Ann Oncol , vol.15 , pp. 201-206
    • Colomer, R.1    Llombart-Cussac, A.2    Lluch, A.3    Barnadas, A.4    Ojeda, B.5    Caranana, V.6
  • 102
    • 49749116113 scopus 로고    scopus 로고
    • Biweekly gemcitabine plus vinorelbine in first-line metastatic breast cancer: efficacy and correlation with HER2 extracellular domain
    • Colomer R., Llombart-Cussac A., Tusquets I., Rifa J., Mayordomo J.I., Ojeda B., et al. Biweekly gemcitabine plus vinorelbine in first-line metastatic breast cancer: efficacy and correlation with HER2 extracellular domain. Clin Transl Oncol 2006, 8:896-902.
    • (2006) Clin Transl Oncol , vol.8 , pp. 896-902
    • Colomer, R.1    Llombart-Cussac, A.2    Tusquets, I.3    Rifa, J.4    Mayordomo, J.I.5    Ojeda, B.6
  • 103
    • 0030757466 scopus 로고    scopus 로고
    • Prediction of response to antiestrogen therapy in advanced breast cancer patients by pretreatment circulating levels of extracellular domain of the HER-2/c-neu protein
    • Yamauchi H., O'Neill A., Gelman R., Carney W., Tenney D.Y., Hosch S., et al. Prediction of response to antiestrogen therapy in advanced breast cancer patients by pretreatment circulating levels of extracellular domain of the HER-2/c-neu protein. J Clin Oncol 1997, 15:2518-2525.
    • (1997) J Clin Oncol , vol.15 , pp. 2518-2525
    • Yamauchi, H.1    O'Neill, A.2    Gelman, R.3    Carney, W.4    Tenney, D.Y.5    Hosch, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.