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Volumn 36, Issue 4, 2003, Pages 233-240

Serum HER-2/neu in the management of breast cancer patients

Author keywords

Breast cancer; Chemotherapy; Herceptin; Hormonal therapy; Monitoring; Monoclonal antibody; neu; Prediction; Prognosis; Screening; Serum HER 2

Indexed keywords

ANTIGEN; CA 15-3 ANTIGEN; CA 27-29 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; METALLOPROTEINASE; MONOCLONAL ANTIBODY; PROTEIN; TRASTUZUMAB; TUMOR MARKER;

EID: 0038796897     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9120(03)00026-2     Document Type: Review
Times cited : (40)

References (38)
  • 1
    • 0020117514 scopus 로고
    • Identification of a phosphoprotein specifically induced by the transforming DNA of rat neuroblastomas
    • Padhy L.C., Shih C., Cowing D., Finkelstein R., Weinberg R.A. Identification of a phosphoprotein specifically induced by the transforming DNA of rat neuroblastomas. Cell. 28:(4):1982;865-871.
    • (1982) Cell , vol.28 , Issue.4 , pp. 865-871
    • Padhy, L.C.1    Shih, C.2    Cowing, D.3    Finkelstein, R.4    Weinberg, R.A.5
  • 2
    • 0022600388 scopus 로고
    • The neu oncogene encodes an epidermal growth factor receptor-related protein
    • Bargmann C.I., Hung M.C., Weinberg R.A. The neu oncogene encodes an epidermal growth factor receptor-related protein. Nature. 319:(6050):1986;226-230.
    • (1986) Nature , vol.319 , Issue.6050 , pp. 226-230
    • Bargmann, C.I.1    Hung, M.C.2    Weinberg, R.A.3
  • 3
    • 0022399581 scopus 로고
    • Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
    • Coussens L., Yang-Feng T.L., Liao Y.C., et al. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science. 230:(4730):1985;1132-1139.
    • (1985) Science , vol.230 , Issue.4730 , pp. 1132-1139
    • Coussens, L.1    Yang-Feng, T.L.2    Liao, Y.C.3
  • 4
    • 0028250050 scopus 로고
    • The c-erbB-2 protein in oncogenesis: Molecular structure to molecular epidemiology
    • Brandt-Rauf P.W., Pincus M.R., Carney W.P. The c-erbB-2 protein in oncogenesis molecular structure to molecular epidemiology . Crit Rev Oncog. 5:(2-3):1994;313-329.
    • (1994) Crit Rev Oncog , vol.5 , Issue.2-3 , pp. 313-329
    • Brandt-Rauf, P.W.1    Pincus, M.R.2    Carney, W.P.3
  • 5
    • 0028230002 scopus 로고
    • Conformation of the transmembrane domain of the epidermal growth factor receptor
    • Brandt-Rauf P.W., Monaco R., Pincus M.R. Conformation of the transmembrane domain of the epidermal growth factor receptor. J Protein Chem. 13:(2):1994;227-231.
    • (1994) J Protein Chem , vol.13 , Issue.2 , pp. 227-231
    • Brandt-Rauf, P.W.1    Monaco, R.2    Pincus, M.R.3
  • 6
    • 0026569360 scopus 로고
    • Three dimensional structure of the transmembrane region of the proto-oncogenic and oncogenic forms of the neu protein
    • Gullick W.J., Bottomley A.C., Lofts F.J., et al. Three dimensional structure of the transmembrane region of the proto-oncogenic and oncogenic forms of the neu protein. EMBO J. 11:(1):1992;43-48.
    • (1992) EMBO J , vol.11 , Issue.1 , pp. 43-48
    • Gullick, W.J.1    Bottomley, A.C.2    Lofts, F.J.3
  • 7
    • 0024593236 scopus 로고
    • Structure and expression of c-erbB-2 and EGF receptor genes in inflammatory and non-inflammatory breast cancer: Prognostic significance
    • Guerin M., Gabillot M., Mathieu M.C., et al. Structure and expression of c-erbB-2 and EGF receptor genes in inflammatory and non-inflammatory breast cancer prognostic significance . Int J Cancer. 43:(2):1989;201-208.
    • (1989) Int J Cancer , vol.43 , Issue.2 , pp. 201-208
    • Guerin, M.1    Gabillot, M.2    Mathieu, M.C.3
  • 8
    • 0033559210 scopus 로고    scopus 로고
    • Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells
    • Codony-Servat J., Albanell J., Lopez-Talavera J.C., Arribas J., Baselga J. Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells. Cancer Res. 59:(6):1999;1196-1201.
    • (1999) Cancer Res , vol.59 , Issue.6 , pp. 1196-1201
    • Codony-Servat, J.1    Albanell, J.2    Lopez-Talavera, J.C.3    Arribas, J.4    Baselga, J.5
  • 9
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon D.J., Clark G.M., Wong S.G., Levin W.J., Ullrich A., McGuire W.L. Human breast cancer correlation of relapse and survival with amplification of the HER-2/neu oncogene . Science. 235:(4785):1987;177-182.
    • (1987) Science , vol.235 , Issue.4785 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 10
    • 0031903646 scopus 로고    scopus 로고
    • Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment
    • Pegram M.D., Lipton A., Hayes D.F., et al. Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment. J Clin Oncol. 16:(8):1998;2659-2671.
    • (1998) J Clin Oncol , vol.16 , Issue.8 , pp. 2659-2671
    • Pegram, M.D.1    Lipton, A.2    Hayes, D.F.3
  • 11
    • 0035874981 scopus 로고    scopus 로고
    • Trastuzumab (herceptin), a humanized anti-her2 receptor monoclonal antibody, inhibits basal and activated her2 ectodomain cleavage in breast cancer cells
    • Molina M.A., Codony-Servat J., Albanell J., Rojo F., Arribas J., Baselga J. Trastuzumab (herceptin), a humanized anti-her2 receptor monoclonal antibody, inhibits basal and activated her2 ectodomain cleavage in breast cancer cells. Cancer Res. 61:(12):2001;4744-4749.
    • (2001) Cancer Res , vol.61 , Issue.12 , pp. 4744-4749
    • Molina, M.A.1    Codony-Servat, J.2    Albanell, J.3    Rojo, F.4    Arribas, J.5    Baselga, J.6
  • 12
    • 0030947407 scopus 로고    scopus 로고
    • HER2 overexpression and paclitaxel sensitivity in breast cancer: Therapeutic implications
    • Baselga J., Seidman A.D., Rosen P.P., Norton L. HER2 overexpression and paclitaxel sensitivity in breast cancer therapeutic implications . Oncology (Huntingt). 11:(3 Suppl 2):1997;43-48.
    • (1997) Oncology (Huntingt) , vol.11 , Issue.3 SUPPL. 2 , pp. 43-48
    • Baselga, J.1    Seidman, A.D.2    Rosen, P.P.3    Norton, L.4
  • 13
    • 0032127350 scopus 로고    scopus 로고
    • Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
    • Baselga J., Norton L., Albanell J., Kim Y.M., Mendelsohn J. Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts. Cancer Res. 58:(13):1998;2825-2831.
    • (1998) Cancer Res , vol.58 , Issue.13 , pp. 2825-2831
    • Baselga, J.1    Norton, L.2    Albanell, J.3    Kim, Y.M.4    Mendelsohn, J.5
  • 14
    • 0035863284 scopus 로고    scopus 로고
    • Her-2/neu analysis in archival tissue samples of human breast cancer: Comparison of immunohistochemistry and fluorescence in situ hybridization
    • Lebeau A., Deimling D., Kaltz C., et al. Her-2/neu analysis in archival tissue samples of human breast cancer comparison of immunohistochemistry and fluorescence in situ hybridization . J Clin Oncol. 19:(2):2001;354-363.
    • (2001) J Clin Oncol , vol.19 , Issue.2 , pp. 354-363
    • Lebeau, A.1    Deimling, D.2    Kaltz, C.3
  • 15
    • 0034327895 scopus 로고    scopus 로고
    • Assessment of methods for tissue-based detection of the HER-2/neu alteration in human breast cancer: A direct comparison of fluorescence in situ hybridization and immunohistochemistry
    • Pauletti G., Dandekar S., Rong H., et al. Assessment of methods for tissue-based detection of the HER-2/neu alteration in human breast cancer a direct comparison of fluorescence in situ hybridization and immunohistochemistry . J Clin Oncol. 18:(21):2000;3651-3664.
    • (2000) J Clin Oncol , vol.18 , Issue.21 , pp. 3651-3664
    • Pauletti, G.1    Dandekar, S.2    Rong, H.3
  • 16
    • 0024348697 scopus 로고
    • Generation and characterization of monoclonal antibodies specific for the human neu oncogene product, p185
    • McKenzie S.J., Marks P.J., Lam T., et al. Generation and characterization of monoclonal antibodies specific for the human neu oncogene product, p185. Oncogene. 4:(5):1989;543-548.
    • (1989) Oncogene , vol.4 , Issue.5 , pp. 543-548
    • McKenzie, S.J.1    Marks, P.J.2    Lam, T.3
  • 17
    • 0035000489 scopus 로고    scopus 로고
    • Clinical utility of serum HER-2/neu testing on the Bayer Immuno 1 automated system in breast cancer
    • Cook G.B., Neaman I.E., Goldblatt J.L., et al. Clinical utility of serum HER-2/neu testing on the Bayer Immuno 1 automated system in breast cancer. Anticancer Res. 21:(2B):2001;1465-1470.
    • (2001) Anticancer Res , vol.21 , Issue.2 B , pp. 1465-1470
    • Cook, G.B.1    Neaman, I.E.2    Goldblatt, J.L.3
  • 19
    • 0030852397 scopus 로고    scopus 로고
    • Hormonal treatment with sex steroids in women is associated with lower p105 serum concentrations
    • Meden H., Mielke S., Marx D., Wuttke W., Kuhn W. Hormonal treatment with sex steroids in women is associated with lower p105 serum concentrations. Anticancer Res. 17:(4B):1997;3075-3077.
    • (1997) Anticancer Res , vol.17 , Issue.4 B , pp. 3075-3077
    • Meden, H.1    Mielke, S.2    Marx, D.3    Wuttke, W.4    Kuhn, W.5
  • 20
    • 0030865749 scopus 로고    scopus 로고
    • Effects of interfering and influencing factors on the analyses of p105 (c-erbB-2/HER-2) oncoprotein fragment in serum
    • Mielke S., Meden H., Raab T., Wuttke W., Kuhn W. Effects of interfering and influencing factors on the analyses of p105 (c-erbB-2/HER-2) oncoprotein fragment in serum. Anticancer Res. 17:(4B):1997;3125-3127.
    • (1997) Anticancer Res , vol.17 , Issue.4 B , pp. 3125-3127
    • Mielke, S.1    Meden, H.2    Raab, T.3    Wuttke, W.4    Kuhn, W.5
  • 21
    • 0031804617 scopus 로고    scopus 로고
    • Plasma c-erbB-2 levels in breast cancer patients: Prognostic significance in predicting response to chemotherapy
    • Mehta R.R., McDermott J.H., Hieken T.J., et al. Plasma c-erbB-2 levels in breast cancer patients prognostic significance in predicting response to chemotherapy . J Clin Oncol. 16:(7):1998;2409-2416.
    • (1998) J Clin Oncol , vol.16 , Issue.7 , pp. 2409-2416
    • Mehta, R.R.1    McDermott, J.H.2    Hieken, T.J.3
  • 22
    • 0009249061 scopus 로고    scopus 로고
    • Correlation of serum erbB-2 concentration with initial clinoco-biological presentation and patients' outcome in primary breast cancer
    • Saghatchian M., Guepratte S., Floiras J.L., Paternostre B., Pichon M.F. Correlation of serum erbB-2 concentration with initial clinoco-biological presentation and patients' outcome in primary breast cancer. Proc ASCO. 20:2001;62b.
    • (2001) Proc ASCO , vol.20
    • Saghatchian, M.1    Guepratte, S.2    Floiras, J.L.3    Paternostre, B.4    Pichon, M.F.5
  • 23
    • 0034813368 scopus 로고    scopus 로고
    • Circulating HER-2/erbB-2/c-neu (HER-2) extracellular domain as a prognostic factor in patients with metastatic breast cancer: Cancer and Leukemia Group B Study 8662
    • Hayes D.F., Yamauchi H., Broadwater G., et al. Circulating HER-2/erbB-2/c-neu (HER-2) extracellular domain as a prognostic factor in patients with metastatic breast cancer Cancer and Leukemia Group B Study 8662 . Clin Cancer Res. 7:(9):2001;2703-2711.
    • (2001) Clin Cancer Res , vol.7 , Issue.9 , pp. 2703-2711
    • Hayes, D.F.1    Yamauchi, H.2    Broadwater, G.3
  • 24
    • 0034691610 scopus 로고    scopus 로고
    • Combined measurement of the c-erbB-2 protein in breast carcinoma tissues and sera is useful as a sensitive tumor marker for monitoring tumor relapse
    • Sugano K., Ushiama M., Fukutomi T., Tsuda H., Kitoh T., Ohkura H. Combined measurement of the c-erbB-2 protein in breast carcinoma tissues and sera is useful as a sensitive tumor marker for monitoring tumor relapse. Int J Cancer. 89:(4):2000;329-336.
    • (2000) Int J Cancer , vol.89 , Issue.4 , pp. 329-336
    • Sugano, K.1    Ushiama, M.2    Fukutomi, T.3    Tsuda, H.4    Kitoh, T.5    Ohkura, H.6
  • 25
    • 0033160432 scopus 로고    scopus 로고
    • Serum c-erB-2 levels in monitoring of operable breast cancer patients
    • Imoto S., Kitoh T., Hasebe T. Serum c-erB-2 levels in monitoring of operable breast cancer patients. Jpn J Clin Oncol. 29:(7):1999;336-339.
    • (1999) Jpn J Clin Oncol , vol.29 , Issue.7 , pp. 336-339
    • Imoto, S.1    Kitoh, T.2    Hasebe, T.3
  • 26
    • 0027979311 scopus 로고
    • Elevated erbB-2 oncoprotein levels in preoperative and follow-up serum samples define an aggressive disease course in patients with breast cancer
    • Isola J.J., Holli K., Oksa H., Teramoto Y., Kallioniemi O.P. Elevated erbB-2 oncoprotein levels in preoperative and follow-up serum samples define an aggressive disease course in patients with breast cancer. Cancer. 73:(3):1994;652-658.
    • (1994) Cancer , vol.73 , Issue.3 , pp. 652-658
    • Isola, J.J.1    Holli, K.2    Oksa, H.3    Teramoto, Y.4    Kallioniemi, O.P.5
  • 27
    • 0032814910 scopus 로고    scopus 로고
    • C-erbB-2, CEA and CA 15.3 serum levels in the early diagnosis of recurrence of breast cancer patients
    • Molina R., Jo J., Filella X., et al. C-erbB-2, CEA and CA 15.3 serum levels in the early diagnosis of recurrence of breast cancer patients. Anticancer Res. 19:(4A):1999;2551-2555.
    • (1999) Anticancer Res , vol.19 , Issue.4 A , pp. 2551-2555
    • Molina, R.1    Jo, J.2    Filella, X.3
  • 28
    • 10144247242 scopus 로고    scopus 로고
    • Utility of C-erbB-2 in tissue and in serum in the early diagnosis of recurrence in breast cancer patients: Comparison with carcinoembryonic antigen and CA 15.3
    • Molina R., Jo J., Zanon G., et al. Utility of C-erbB-2 in tissue and in serum in the early diagnosis of recurrence in breast cancer patients comparison with carcinoembryonic antigen and CA 15.3 . Br J Cancer. 74:(7):1996;1126-1131.
    • (1996) Br J Cancer , vol.74 , Issue.7 , pp. 1126-1131
    • Molina, R.1    Jo, J.2    Zanon, G.3
  • 29
    • 0034082031 scopus 로고    scopus 로고
    • Circulating HER2 extracellular domain and resistance to chemotherapy in advanced breast cancer
    • Colomer R., Montero S., Lluch A., et al. Circulating HER2 extracellular domain and resistance to chemotherapy in advanced breast cancer. Clin Cancer Res. 6:(6):2000;2356-2362.
    • (2000) Clin Cancer Res , vol.6 , Issue.6 , pp. 2356-2362
    • Colomer, R.1    Montero, S.2    Lluch, A.3
  • 30
    • 0035868650 scopus 로고    scopus 로고
    • Comparison of methods of measuring HER-2 in metastatic breast cancer patients treated with high-dose chemotherapy
    • Harris L.N., Liotcheva V., Broadwater G., et al. Comparison of methods of measuring HER-2 in metastatic breast cancer patients treated with high-dose chemotherapy. J Clin Oncol. 19:(6):2001;1698-1706.
    • (2001) J Clin Oncol , vol.19 , Issue.6 , pp. 1698-1706
    • Harris, L.N.1    Liotcheva, V.2    Broadwater, G.3
  • 31
    • 0037087535 scopus 로고    scopus 로고
    • Elevated serum her-2/neu level predicts decreased response to hormone therapy in metastatic breast cancer
    • Lipton A., Ali S.M., Leitzel K., et al. Elevated serum her-2/neu level predicts decreased response to hormone therapy in metastatic breast cancer. J Clin Oncol. 20:(6):2002;1467-1472.
    • (2002) J Clin Oncol , vol.20 , Issue.6 , pp. 1467-1472
    • Lipton, A.1    Ali, S.M.2    Leitzel, K.3
  • 32
    • 0035884620 scopus 로고    scopus 로고
    • Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: Evidence from a phase III randomized trial
    • Ellis M.J., Coop A., Singh B., et al. Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer evidence from a phase III randomized trial . J Clin Oncol. 19:(18):2001;3808-3816.
    • (2001) J Clin Oncol , vol.19 , Issue.18 , pp. 3808-3816
    • Ellis, M.J.1    Coop, A.2    Singh, B.3
  • 33
    • 0036534121 scopus 로고    scopus 로고
    • Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer
    • Esteva F.J., Valero V., Booser D., et al. Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer. J Clin Oncol. 20:(7):2002;1800-1808.
    • (2002) J Clin Oncol , vol.20 , Issue.7 , pp. 1800-1808
    • Esteva, F.J.1    Valero, V.2    Booser, D.3
  • 34
    • 12444311337 scopus 로고    scopus 로고
    • Monitoring clinical response to Herceptin-based therapy by serum HER-2/neu measurements in metastatic breast cancer
    • Lüftner D., Fritz J., Fenner M., et al. Monitoring clinical response to Herceptin-based therapy by serum HER-2/neu measurements in metastatic breast cancer. Clin Chem Lab Med. 39:2001;178.
    • (2001) Clin Chem Lab Med , vol.39 , pp. 178
    • Lüftner, D.1    Fritz, J.2    Fenner, M.3
  • 35
    • 0038016899 scopus 로고    scopus 로고
    • Predictive value of serum HER-2/neu extracellular domain (ECd) during trastuzumab-based therapy in patients with breast cancer
    • Kostler W.J., Schwab B., Singer C., et al. Predictive value of serum HER-2/neu extracellular domain (ECd) during trastuzumab-based therapy in patients with breast cancer. Proc AACR. 43:2002;490.
    • (2002) Proc AACR , vol.43 , pp. 490
    • Kostler, W.J.1    Schwab, B.2    Singer, C.3
  • 36
    • 0035868668 scopus 로고    scopus 로고
    • 2000 update of recommendations for the use of tumor markers in breast and colorectal cancer: Clinical practice guidelines of the American Society of Clinical Oncology
    • Bast R.C. Jr, Ravdin P., Hayes D.F., et al. 2000 update of recommendations for the use of tumor markers in breast and colorectal cancer clinical practice guidelines of the American Society of Clinical Oncology . J Clin Oncol. 19:(6):2001;1865-1878.
    • (2001) J Clin Oncol , vol.19 , Issue.6 , pp. 1865-1878
    • Bast R.C., Jr.1    Ravdin, P.2    Hayes, D.F.3
  • 37
    • 0001875348 scopus 로고    scopus 로고
    • HER-2/neu/ErbB-2 status by immunohistochemistry and FISH: Clonality and progression with recurrence and metastases
    • Edgerton S.M., Merkel D.E., Moore D.H., Thor A.D. HER-2/neu/ErbB-2 status by immunohistochemistry and FISH clonality and progression with recurrence and metastases . Breast Cancer Res Treat. 64:(1):2000;55.
    • (2000) Breast Cancer Res Treat , vol.64 , Issue.1 , pp. 55
    • Edgerton, S.M.1    Merkel, D.E.2    Moore, D.H.3    Thor, A.D.4
  • 38
    • 0035266243 scopus 로고    scopus 로고
    • ErbB2 overexpression on occult metastatic cells in bone marrow predicts poor clinical outcome of stage I-III breast cancer patients
    • Braun S., Schlimok G., Heumos I., et al. ErbB2 overexpression on occult metastatic cells in bone marrow predicts poor clinical outcome of stage I-III breast cancer patients. Cancer Res. 61:(5):2001;1890-1895.
    • (2001) Cancer Res , vol.61 , Issue.5 , pp. 1890-1895
    • Braun, S.1    Schlimok, G.2    Heumos, I.3


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