Liver sinusoidal endothelial cells are the principal site for elimination of unfractionated heparin from the circulation

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 294, Issue 2, 2008, Pages

  Øie, Cristina Ionica ^a,c   Olsen, Randi ^b   Smedsrød, Bård ^c   Hansen, John Bjarne ^a  

^a Institute of Clinical Medicine   (Norway)

^b Faculty of Medicine

^c UNIVERSITY OF TROMSØ   (Norway)

Author keywords

Clearance; Fluorescence microscopy; Receptor mediated endocytosis

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; GLYCOSAMINOGLYCAN; HEPARIN; IODINE 125; STABILIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CIRCULATION; CONTROLLED STUDY; DRUG ELIMINATION; DRUG HALF LIFE; FLUORESCENCE MICROSCOPY; IMMUNOGOLD ELECTRON MICROSCOPY; KUPFFER CELL; LIVER SINUSOID; MALE; NONHUMAN; PLASMA CLEARANCE; PRIORITY JOURNAL; RAT;

ANIMALS; ANTICOAGULANTS; BIOLOGICAL TRANSPORT, ACTIVE; ENDOCYTOSIS; EPITHELIAL CELLS; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; HEPARIN; HEPATOCYTES; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MICROSCOPY, PHASE-CONTRAST; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

EID: 39149126685     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00489.2007     Document Type: Article

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