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Volumn 57, Issue 6, 2011, Pages 641-652

Clinical, molecular, and genomic changes in response to a left ventricular assist device

Author keywords

beta adrenergic; calcium; clinical trials; gene expression; integrins; microarray; miRNA; ventricular assist device

Indexed keywords

ARTICLE; CLINICAL ASSESSMENT; FOOD AND DRUG ADMINISTRATION; FUNCTIONAL ASSESSMENT; GENE EXPRESSION; HEART ASSIST DEVICE; HEART FAILURE; HEART TRANSPLANTATION; HUMAN; MEDICAID; MEDICARE; MOLECULAR GENETICS; PRIORITY JOURNAL; QUALITY OF LIFE; REGISTER; SURVIVAL;

EID: 79551528796     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2010.11.010     Document Type: Review
Times cited : (102)

References (55)
  • 1
    • 63849177462 scopus 로고    scopus 로고
    • 2009 focused update incorporated into the ACC/AHA 2005 guidelines for the diagnosis and management of heart failure in adults: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
    • S.A. Hunt, W.T. Abraham, and M.H. Chin 2009 focused update incorporated into the ACC/AHA 2005 guidelines for the diagnosis and management of heart failure in adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines J Am Coll Cardiol 53 2009 e1 e90
    • (2009) J Am Coll Cardiol , vol.53
    • Hunt, S.A.1    Abraham, W.T.2    Chin, M.H.3
  • 3
    • 72249109546 scopus 로고    scopus 로고
    • Second INTERMACS annual report: More than 1,000 primary left ventricular assist device implants
    • J.K. Kirklin, D.C. Naftel, and R.L. Kormos Second INTERMACS annual report: more than 1,000 primary left ventricular assist device implants J Heart Lung Transplant 29 2010 1 10
    • (2010) J Heart Lung Transplant , vol.29 , pp. 1-10
    • Kirklin, J.K.1    Naftel, D.C.2    Kormos, R.L.3
  • 4
    • 34548311569 scopus 로고    scopus 로고
    • Use of a continuous-flow device in patients awaiting heart transplantation
    • L.W. Miller, F.D. Pagani, and S.D. Russell Use of a continuous-flow device in patients awaiting heart transplantation N Engl J Med 357 2007 885 896
    • (2007) N Engl J Med , vol.357 , pp. 885-896
    • Miller, L.W.1    Pagani, F.D.2    Russell, S.D.3
  • 5
    • 73349129701 scopus 로고    scopus 로고
    • Advanced heart failure treated with continuous-flow left ventricular assist device
    • M.S. Slaughter, J.G. Rogers, and C.A. Milano Advanced heart failure treated with continuous-flow left ventricular assist device N Engl J Med 361 2009 2241 2251
    • (2009) N Engl J Med , vol.361 , pp. 2241-2251
    • Slaughter, M.S.1    Rogers, J.G.2    Milano, C.A.3
  • 6
    • 0032909782 scopus 로고    scopus 로고
    • The REMATCH trial: Rationale, design, and end points
    • E.A. Rose, A.J. Moskowitz, and M. Packer The REMATCH trial: rationale, design, and end points Ann Thorac Surg 67 1999 723 730
    • (1999) Ann Thorac Surg , vol.67 , pp. 723-730
    • Rose, E.A.1    Moskowitz, A.J.2    Packer, M.3
  • 7
    • 4143097042 scopus 로고    scopus 로고
    • Altered myocardial Ca2+ cycling after left ventricular assist device support in the failing human heart
    • K.W. Chaudhary, E.I. Rossman, and V. Piacentino III Altered myocardial Ca2+ cycling after left ventricular assist device support in the failing human heart J Am Coll Cardiol 44 2004 837 845
    • (2004) J Am Coll Cardiol , vol.44 , pp. 837-845
    • Chaudhary, K.W.1    Rossman, E.I.2    Iii, P.V.3
  • 8
    • 0032537621 scopus 로고    scopus 로고
    • Myocyte recovery after mechanical circulatory support in humans with end-stage heart failure
    • K. Dipla, J.A. Mattiello, V. Jeevanandam, S.R. Houser, and K.B. Margulies Myocyte recovery after mechanical circulatory support in humans with end-stage heart failure Circulation 97 1998 2316 2322
    • (1998) Circulation , vol.97 , pp. 2316-2322
    • Dipla, K.1    Mattiello, J.A.2    Jeevanandam, V.3    Houser, S.R.4    Margulies, K.B.5
  • 9
    • 0035845673 scopus 로고    scopus 로고
    • Electrophysiological alterations after mechanical circulatory support in patients with advanced cardiac failure
    • J.D. Harding, V. Piacentino III, J.P. Gaughan, S.R. Houser, and K.B. Margulies Electrophysiological alterations after mechanical circulatory support in patients with advanced cardiac failure Circulation 104 2001 1241 1247
    • (2001) Circulation , vol.104 , pp. 1241-1247
    • Harding, J.D.1    Iii, P.V.2    Gaughan, J.P.3    Houser, S.R.4    Margulies, K.B.5
  • 10
    • 0034727712 scopus 로고    scopus 로고
    • Chronic unloading by left ventricular assist device reverses contractile dysfunction and alters gene expression in end-stage heart failure
    • P.M. Heerdt, J.W. Holmes, and B. Cai Chronic unloading by left ventricular assist device reverses contractile dysfunction and alters gene expression in end-stage heart failure Circulation 102 2000 2713 2719
    • (2000) Circulation , vol.102 , pp. 2713-2719
    • Heerdt, P.M.1    Holmes, J.W.2    Cai, B.3
  • 11
    • 0036956836 scopus 로고    scopus 로고
    • Reversal mechanisms of left ventricular remodeling: Lessons from left ventricular assist device experiments
    • K.B. Margulies Reversal mechanisms of left ventricular remodeling: lessons from left ventricular assist device experiments J Card Fail 8 2002 S500 S505
    • (2002) J Card Fail , vol.8
    • Margulies, K.B.1
  • 12
    • 34248586648 scopus 로고    scopus 로고
    • Cardiac improvement during mechanical circulatory support: A prospective multicenter study of the LVAD Working Group
    • S. Maybaum, D. Mancini, and S. Xydas Cardiac improvement during mechanical circulatory support: a prospective multicenter study of the LVAD Working Group Circulation 115 2007 2497 2505
    • (2007) Circulation , vol.115 , pp. 2497-2505
    • Maybaum, S.1    Mancini, D.2    Xydas, S.3
  • 13
    • 0035928837 scopus 로고    scopus 로고
    • Mechanical unloading restores beta-adrenergic responsiveness and reverses receptor downregulation in the failing human heart
    • M.L. Ogletree-Hughes, L.B. Stull, W.E. Sweet, N.G. Smedira, P.M. McCarthy, and C.S. Moravec Mechanical unloading restores beta-adrenergic responsiveness and reverses receptor downregulation in the failing human heart Circulation 104 2001 881 886
    • (2001) Circulation , vol.104 , pp. 881-886
    • Ogletree-Hughes, M.L.1    Stull, L.B.2    Sweet, W.E.3    Smedira, N.G.4    McCarthy, P.M.5    Moravec, C.S.6
  • 14
    • 0032544226 scopus 로고    scopus 로고
    • Regression of cellular hypertrophy after left ventricular assist device support
    • A. Zafeiridis, V. Jeevanandam, S.R. Houser, and K.B. Margulies Regression of cellular hypertrophy after left ventricular assist device support Circulation 98 1998 656 662
    • (1998) Circulation , vol.98 , pp. 656-662
    • Zafeiridis, A.1    Jeevanandam, V.2    Houser, S.R.3    Margulies, K.B.4
  • 15
    • 14044258352 scopus 로고    scopus 로고
    • Left ventricular assist device support normalizes left and right ventricular beta-adrenergic pathway properties
    • S. Klotz, A. Barbone, and S. Reiken Left ventricular assist device support normalizes left and right ventricular beta-adrenergic pathway properties J Am Coll Cardiol 45 2005 668 676
    • (2005) J Am Coll Cardiol , vol.45 , pp. 668-676
    • Klotz, S.1    Barbone, A.2    Reiken, S.3
  • 16
    • 33947156882 scopus 로고    scopus 로고
    • The impact of angiotensin-converting enzyme inhibitor therapy on the extracellular collagen matrix during left ventricular assist device support in patients with end-stage heart failure
    • S. Klotz, A.H. Danser, and R.F. Foronjy The impact of angiotensin-converting enzyme inhibitor therapy on the extracellular collagen matrix during left ventricular assist device support in patients with end-stage heart failure J Am Coll Cardiol 49 2007 1166 1174
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1166-1174
    • Klotz, S.1    Danser, A.H.2    Foronjy, R.F.3
  • 17
    • 33750500333 scopus 로고    scopus 로고
    • Left ventricular assist device and drug therapy for the reversal of heart failure
    • E.J. Birks, P.D. Tansley, and J. Hardy Left ventricular assist device and drug therapy for the reversal of heart failure N Engl J Med 355 2006 1873 1884
    • (2006) N Engl J Med , vol.355 , pp. 1873-1884
    • Birks, E.J.1    Tansley, P.D.2    Hardy, J.3
  • 18
    • 34247620544 scopus 로고    scopus 로고
    • Molecular signature of recovery following combination left ventricular assist device (LVAD) support and pharmacologic therapy
    • J.L. Hall, E.J. Birks, and S. Grindle Molecular signature of recovery following combination left ventricular assist device (LVAD) support and pharmacologic therapy Eur Heart J 28 2007 613 627
    • (2007) Eur Heart J , vol.28 , pp. 613-627
    • Hall, J.L.1    Birks, E.J.2    Grindle, S.3
  • 19
    • 34248597852 scopus 로고    scopus 로고
    • The role of the cardiac Na+/Ca2+ exchanger in reverse remodeling: Relevance for LVAD-recovery
    • C.M. Terracciano, M.U. Koban, and G.K. Soppa The role of the cardiac Na+/Ca2+ exchanger in reverse remodeling: relevance for LVAD-recovery Ann N Y Acad Sci 1099 2007 349 360
    • (2007) Ann N y Acad Sci , vol.1099 , pp. 349-360
    • Terracciano, C.M.1    Koban, M.U.2    Soppa, G.K.3
  • 20
    • 0347990624 scopus 로고    scopus 로고
    • Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell
    • G.G. Holz Epac: a new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell Diabetes 53 2004 5 13
    • (2004) Diabetes , vol.53 , pp. 5-13
    • Holz, G.G.1
  • 21
    • 25444520038 scopus 로고    scopus 로고
    • PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis
    • S. Seino, and T. Shibasaki PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis Physiol Rev 85 2005 1303 1342
    • (2005) Physiol Rev , vol.85 , pp. 1303-1342
    • Seino, S.1    Shibasaki, T.2
  • 22
    • 0037144097 scopus 로고    scopus 로고
    • 2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices
    • 2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices Circ Res 91 2002 517 524
    • (2002) Circ Res , vol.91 , pp. 517-524
    • Chen, X.1    Piacentino III, V.2    Furukawa, S.3    Goldman, B.4    Margulies, K.B.5    Houser, S.R.6
  • 23
    • 0034640113 scopus 로고    scopus 로고
    • Pka phosphorylation dissociates fkbp12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
    • S.O. Marx, S. Reiken, and Y. Hisamatsu Pka phosphorylation dissociates fkbp12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts Cell 101 2000 365 376
    • (2000) Cell , vol.101 , pp. 365-376
    • Marx, S.O.1    Reiken, S.2    Hisamatsu, Y.3
  • 24
    • 0041743798 scopus 로고    scopus 로고
    • Changes in sarcolemmal ca entry and sarcoplasmic reticulum ca content in ventricular myocytes from patients with end-stage heart failure following myocardial recovery after combined pharmacological and ventricular assist device therapy
    • C.M. Terracciano, S.E. Harding, and D. Adamson Changes in sarcolemmal ca entry and sarcoplasmic reticulum ca content in ventricular myocytes from patients with end-stage heart failure following myocardial recovery after combined pharmacological and ventricular assist device therapy Eur Heart J 24 2003 1329 1339
    • (2003) Eur Heart J , vol.24 , pp. 1329-1339
    • Terracciano, C.M.1    Harding, S.E.2    Adamson, D.3
  • 25
    • 0032727086 scopus 로고    scopus 로고
    • Left ventricular assist system as a bridge to myocardial recovery
    • O.H. Frazier, and T.J. Myers Left ventricular assist system as a bridge to myocardial recovery Ann Thorac Surg 68 1999 734 741
    • (1999) Ann Thorac Surg , vol.68 , pp. 734-741
    • Frazier, O.H.1    Myers, T.J.2
  • 26
    • 2442652789 scopus 로고    scopus 로고
    • Clinical recovery from end-stage heart failure using left-ventricular assist device and pharmacological therapy correlates with increased sarcoplasmic reticulum calcium content but not with regression of cellular hypertrophy
    • C.M. Terracciano, J. Hardy, E.J. Birks, A. Khaghani, N.R. Banner, and M.H. Yacoub Clinical recovery from end-stage heart failure using left-ventricular assist device and pharmacological therapy correlates with increased sarcoplasmic reticulum calcium content but not with regression of cellular hypertrophy Circulation 109 2004 2263 2265
    • (2004) Circulation , vol.109 , pp. 2263-2265
    • Terracciano, C.M.1    Hardy, J.2    Birks, E.J.3    Khaghani, A.4    Banner, N.R.5    Yacoub, M.H.6
  • 27
    • 77950517612 scopus 로고    scopus 로고
    • Duration of left ventricular assist device support: Effects on abnormal calcium cycling and functional recovery in the failing human heart
    • M.L. Ogletree, W.E. Sweet, and C. Talerico Duration of left ventricular assist device support: Effects on abnormal calcium cycling and functional recovery in the failing human heart J Heart Lung Transplant 29 2010 554 561
    • (2010) J Heart Lung Transplant , vol.29 , pp. 554-561
    • Ogletree, M.L.1    Sweet, W.E.2    Talerico, C.3
  • 28
    • 62649133817 scopus 로고    scopus 로고
    • Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID trial), a first-in-human phase 1/2 clinical trial
    • B.E. Jaski, M.L. Jessup, and D.M. Mancini Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID trial), a first-in-human phase 1/2 clinical trial J Card Fail 15 2009 171 181
    • (2009) J Card Fail , vol.15 , pp. 171-181
    • Jaski, B.E.1    Jessup, M.L.2    Mancini, D.M.3
  • 29
    • 24644483113 scopus 로고    scopus 로고
    • Gene profiling changes in cytoskeletal proteins during clinical recovery after left ventricular-assist device support
    • E.J. Birks, J.L. Hall, and P.J. Barton Gene profiling changes in cytoskeletal proteins during clinical recovery after left ventricular-assist device support Circulation 112 2005 I57 I64
    • (2005) Circulation , vol.112
    • Birks, E.J.1    Hall, J.L.2    Barton, P.J.3
  • 30
    • 0037050022 scopus 로고    scopus 로고
    • The failing heart
    • J.A. Towbin, and N.E. Bowles The failing heart Nature 415 2002 227 233
    • (2002) Nature , vol.415 , pp. 227-233
    • Towbin, J.A.1    Bowles, N.E.2
  • 31
    • 67349145927 scopus 로고    scopus 로고
    • A gene expression profile of the myocardial response to clenbuterol
    • E. Lara-Pezzi, C.M. Terracciano, and G.K. Soppa A gene expression profile of the myocardial response to clenbuterol J Cardiovasc Transl Res 2 2009 191 197
    • (2009) J Cardiovasc Transl Res , vol.2 , pp. 191-197
    • Lara-Pezzi, E.1    Terracciano, C.M.2    Soppa, G.K.3
  • 32
    • 33747163976 scopus 로고    scopus 로고
    • Myocardial expression of the arginine:glycine amidinotransferase gene is elevated in heart failure and normalized after recovery: Potential implications for local creatine synthesis
    • M.E. Cullen, A.H. Yuen, and L.E. Felkin Myocardial expression of the arginine:glycine amidinotransferase gene is elevated in heart failure and normalized after recovery: potential implications for local creatine synthesis Circulation 114 2006 I16 I20
    • (2006) Circulation , vol.114
    • Cullen, M.E.1    Yuen, A.H.2    Felkin, L.E.3
  • 33
    • 24644439147 scopus 로고    scopus 로고
    • Myocardial insulin-like growth factor-I gene expression during recovery from heart failure after combined left ventricular assist device and clenbuterol therapy
    • P.J. Barton, L.E. Felkin, and E.J. Birks Myocardial insulin-like growth factor-I gene expression during recovery from heart failure after combined left ventricular assist device and clenbuterol therapy Circulation 112 2005 I46 I50
    • (2005) Circulation , vol.112
    • Barton, P.J.1    Felkin, L.E.2    Birks, E.J.3
  • 34
    • 3042802300 scopus 로고    scopus 로고
    • Genomic profiling of the human heart before and after mechanical support with a ventricular assist device reveals alterations in vascular signaling networks
    • J.L. Hall, S. Grindle, and X. Han Genomic profiling of the human heart before and after mechanical support with a ventricular assist device reveals alterations in vascular signaling networks Physiol Genomics 17 2004 283 291
    • (2004) Physiol Genomics , vol.17 , pp. 283-291
    • Hall, J.L.1    Grindle, S.2    Han, X.3
  • 35
    • 79952792120 scopus 로고    scopus 로고
    • Clenbuterol induces cardiac myocyte hypertrophy via paracrine signalling and fibroblast-derived IGF-1
    • P.K. Bhavsar, N.J. Brand, and L.E. Felkin Clenbuterol induces cardiac myocyte hypertrophy via paracrine signalling and fibroblast-derived IGF-1 J Cardiovasc Transl Res 3 2010 688 695
    • (2010) J Cardiovasc Transl Res , vol.3 , pp. 688-695
    • Bhavsar, P.K.1    Brand, N.J.2    Felkin, L.E.3
  • 38
    • 63649096271 scopus 로고    scopus 로고
    • Reciprocal regulation of myocardial microRNAs and messenger RNA in human cardiomyopathy and reversal of the microRNA signature by biomechanical support
    • S.J. Matkovich, D.J. Van Booven, and K.A. Youker Reciprocal regulation of myocardial microRNAs and messenger RNA in human cardiomyopathy and reversal of the microRNA signature by biomechanical support Circulation 119 2009 1263 1271
    • (2009) Circulation , vol.119 , pp. 1263-1271
    • Matkovich, S.J.1    Van Booven, D.J.2    Youker, K.A.3
  • 39
    • 33845317603 scopus 로고    scopus 로고
    • A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure
    • E. van Rooij, L.B. Sutherland, and N. Liu A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure Proc Natl Acad Sci U S A 103 2006 18255 18260
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 18255-18260
    • Van Rooij, E.1    Sutherland, L.B.2    Liu, N.3
  • 40
    • 34249729491 scopus 로고    scopus 로고
    • Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy
    • M. Tatsuguchi, H.Y. Seok, and T.E. Callis Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy J Mol Cell Cardiol 42 2007 1137 1141
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 1137-1141
    • Tatsuguchi, M.1    Seok, H.Y.2    Callis, T.E.3
  • 41
    • 5444222884 scopus 로고    scopus 로고
    • Left ventricular assist device support reverses altered cardiac expression and function of natriuretic peptides and receptors in end-stage heart failure
    • M. Kuhn, M. Voss, and D. Mitko Left ventricular assist device support reverses altered cardiac expression and function of natriuretic peptides and receptors in end-stage heart failure Cardiovasc Res 64 2004 308 314
    • (2004) Cardiovasc Res , vol.64 , pp. 308-314
    • Kuhn, M.1    Voss, M.2    Mitko, D.3
  • 42
    • 24644522768 scopus 로고    scopus 로고
    • Does the beta2-agonist clenbuterol help to maintain myocardial potential to recover during mechanical unloading?
    • H. Tsuneyoshi, W. Oriyanhan, and H. Kanemitsu Does the beta2-agonist clenbuterol help to maintain myocardial potential to recover during mechanical unloading? Circulation 112 2005 I51 I56
    • (2005) Circulation , vol.112
    • Tsuneyoshi, H.1    Oriyanhan, W.2    Kanemitsu, H.3
  • 43
    • 58649084358 scopus 로고    scopus 로고
    • Chronic partial unloading restores beta-adrenergic responsiveness and reverses receptor downregulation in failing rat hearts
    • J. Wang, M. Tsukashita, and T. Nishina Chronic partial unloading restores beta-adrenergic responsiveness and reverses receptor downregulation in failing rat hearts J Thorac Cardiovasc Surg 137 2009 465 470
    • (2009) J Thorac Cardiovasc Surg , vol.137 , pp. 465-470
    • Wang, J.1    Tsukashita, M.2    Nishina, T.3
  • 44
    • 34548297488 scopus 로고    scopus 로고
    • Myocardial production of chromogranin A in human heart: A new regulatory peptide of cardiac function
    • M. Pieroni, A. Corti, and B. Tota Myocardial production of chromogranin A in human heart: a new regulatory peptide of cardiac function Eur Heart J 28 2007 1117 1127
    • (2007) Eur Heart J , vol.28 , pp. 1117-1127
    • Pieroni, M.1    Corti, A.2    Tota, B.3
  • 45
    • 40949160965 scopus 로고    scopus 로고
    • Decreased myocardial chromogranin a expression and colocalization with brain natriuretic peptide during reverse cardiac remodeling after ventricular unloading
    • J. Wohlschlaeger, M. von Winterfeld, and H. Milting Decreased myocardial chromogranin a expression and colocalization with brain natriuretic peptide during reverse cardiac remodeling after ventricular unloading J Heart Lung Transplant 27 2008 442 449
    • (2008) J Heart Lung Transplant , vol.27 , pp. 442-449
    • Wohlschlaeger, J.1    Von Winterfeld, M.2    Milting, H.3
  • 46
    • 16244378559 scopus 로고    scopus 로고
    • Mixed messages: Transcription patterns in failing and recovering human myocardium
    • K.B. Margulies, S. Matiwala, C. Cornejo, H. Olsen, W.A. Craven, and D. Bednarik Mixed messages: transcription patterns in failing and recovering human myocardium Circ Res 96 2005 592 599
    • (2005) Circ Res , vol.96 , pp. 592-599
    • Margulies, K.B.1    Matiwala, S.2    Cornejo, C.3    Olsen, H.4    Craven, W.A.5    Bednarik, D.6
  • 47
    • 77955298123 scopus 로고    scopus 로고
    • Impact of mechanical unloading on microvasculature and associated central remodeling features of the failing human heart
    • S.G. Drakos, A.G. Kfoury, and E.H. Hammond Impact of mechanical unloading on microvasculature and associated central remodeling features of the failing human heart J Am Coll Cardiol 56 2010 382 391
    • (2010) J Am Coll Cardiol , vol.56 , pp. 382-391
    • Drakos, S.G.1    Kfoury, A.G.2    Hammond, E.H.3
  • 48
    • 41449086790 scopus 로고    scopus 로고
    • Cardiac plasticity
    • J.A. Hill, and E.N. Olson Cardiac plasticity N Engl J Med 358 2008 1370 1380
    • (2008) N Engl J Med , vol.358 , pp. 1370-1380
    • Hill, J.A.1    Olson, E.N.2
  • 49
    • 0347987907 scopus 로고    scopus 로고
    • The ubiquitin-proteasome system in cardiovascular diseases - A hypothesis extended
    • J. Herrmann, A. Ciechanover, L.O. Lerman, and A. Lerman The ubiquitin-proteasome system in cardiovascular diseases-a hypothesis extended Cardiovasc Res 61 2004 11 21
    • (2004) Cardiovasc Res , vol.61 , pp. 11-21
    • Herrmann, J.1    Ciechanover, A.2    Lerman, L.O.3    Lerman, A.4
  • 50
    • 22544457940 scopus 로고    scopus 로고
    • Mechanical unloading during left ventricular assist device support increases left ventricular collagen cross-linking and myocardial stiffness
    • S. Klotz, R.F. Foronjy, and M.L. Dickstein Mechanical unloading during left ventricular assist device support increases left ventricular collagen cross-linking and myocardial stiffness Circulation 112 2005 364 374
    • (2005) Circulation , vol.112 , pp. 364-374
    • Klotz, S.1    Foronjy, R.F.2    Dickstein, M.L.3
  • 51
    • 0029050016 scopus 로고
    • Effects of long-term enalapril therapy on cardiac structure and function in patients with left ventricular dysfunction: Results of the SOLVD Echocardiography substudy
    • B. Greenberg, M.A. Quinones, and C. Koilpillai Effects of long-term enalapril therapy on cardiac structure and function in patients with left ventricular dysfunction: results of the SOLVD Echocardiography substudy Circulation 91 1995 2573 2581
    • (1995) Circulation , vol.91 , pp. 2573-2581
    • Greenberg, B.1    Quinones, M.A.2    Koilpillai, C.3
  • 52
    • 0026321084 scopus 로고
    • DNA synthesis in the non-infarcted cardiac interstitium after left coronary artery ligation in the rat: Effects of captopril
    • C. van Krimpen, J.F. Smits, and J.P. Cleutjens DNA synthesis in the non-infarcted cardiac interstitium after left coronary artery ligation in the rat: effects of captopril J Mol Cell Cardiol 23 1991 1245 1253
    • (1991) J Mol Cell Cardiol , vol.23 , pp. 1245-1253
    • Van Krimpen, C.1    Smits, J.F.2    Cleutjens, J.P.3
  • 53
    • 0034682591 scopus 로고    scopus 로고
    • Mechanical unloading versus neurohumoral stimulation on myocardial structure and endocrine function in vivo
    • O. Lisy, M.M. Redfield, and S. Jovanovic Mechanical unloading versus neurohumoral stimulation on myocardial structure and endocrine function in vivo Circulation 102 2000 338 343
    • (2000) Circulation , vol.102 , pp. 338-343
    • Lisy, O.1    Redfield, M.M.2    Jovanovic, S.3
  • 55
    • 0036896297 scopus 로고    scopus 로고
    • Heterotopic transplantation as a model to study functional recovery of unloaded failing hearts
    • H.T. Tevaearai, G.B. Walton, A.D. Eckhart, J.R. Keys, and W.J. Koch Heterotopic transplantation as a model to study functional recovery of unloaded failing hearts J Thorac Cardiovasc Surg 124 2002 1149 1156
    • (2002) J Thorac Cardiovasc Surg , vol.124 , pp. 1149-1156
    • Tevaearai, H.T.1    Walton, G.B.2    Eckhart, A.D.3    Keys, J.R.4    Koch, W.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.