Clenbuterol induces cardiac myocyte hypertrophy via paracrine signalling and fibroblast-derived IGF-1

Journal of Cardiovascular Translational Research

Volumn 3, Issue 6, 2010, Pages 688-695

  Bhavsar, Pankaj K ^a   Brand, Nigel J ^a   Felkin, Leanne E ^a   Luther, Pradeep K ^a   Cullen, Martin E ^a   Yacoub, Magdi H ^a   Barton, Paul J R ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Cardiac fibroblast; Cardiac myocyte; Clenbuterol; Hypertrophy

Indexed keywords

ACTIN; ATRIAL NATRIURETIC FACTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRAIN NATRIURETIC PEPTIDE; CLENBUTEROL; INSULIN LIKE GROWTH FACTOR 1, RAT; INSULIN-LIKE GROWTH FACTOR-1, RAT; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE INHIBITOR; SOMATOMEDIN C;

ANIMAL; ARTICLE; CARDIOMEGALY; CELL CULTURE; CELL SIZE; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; FIBROBLAST; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HEART MUSCLE CELL; METABOLISM; NEWBORN; PARACRINE SIGNALING; PATHOLOGY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; TIME; WESTERN BLOTTING;

ACTINS; ADRENERGIC BETA-2 RECEPTOR AGONISTS; ANIMALS; ANIMALS, NEWBORN; ATRIAL NATRIURETIC FACTOR; BLOTTING, WESTERN; CARDIOMEGALY; CELL SIZE; CELLS, CULTURED; CLENBUTEROL; FIBROBLASTS; GENE EXPRESSION REGULATION; INSULIN-LIKE GROWTH FACTOR I; MYOCYTES, CARDIAC; NATRIURETIC PEPTIDE, BRAIN; PARACRINE COMMUNICATION; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TRANSFECTION;

EID: 79952792120     PISSN: 19375387     EISSN: 19375395     Source Type: Journal    
DOI: 10.1007/s12265-010-9199-1     Document Type: Article

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