Systemic exposure to armodafinil and its tolerability in healthy elderly versus young men: An open-label, multiple-dose, parallel-group study

Drugs and Aging

Volumn 28, Issue 2, 2011, Pages 139-150

  Darwish, Mona ^a   Kirby, Mary ^a   Hellriegel, Edward T ^a   Yang, Ronghua ^a   Robertson, Philmore ^a  

^a CEPHALON INC   (United States)

Author keywords

Armodafinil, pharmacokinetics; Armodafinil, therapeutic use; Elderly; Research and development

Indexed keywords

ARMODAFINIL; DRUG METABOLITE; MODAFINIL ACID; MODAFINIL SULFONE; UNCLASSIFIED DRUG;

ABDOMINAL DISCOMFORT; ABDOMINAL PAIN; ADULT; AGE DISTRIBUTION; AGED; ANXIETY; AREA UNDER THE CURVE; ARTHRALGIA; ARTICLE; BACKACHE; CONTROLLED STUDY; DEPRESSION; DIZZINESS; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG EXPOSURE; DRUG HALF LIFE; DRUG TOLERABILITY; DYSPEPSIA; ELECTROCARDIOGRAM; FOLLICULITIS; HEADACHE; HUMAN; HUMAN EXPERIMENT; HYPEREMIA; HYPERTENSION; INSOMNIA; LABORATORY TEST; LIMB PAIN; LYMPHOCYTOPENIA; MALE; MAXIMUM PLASMA CONCENTRATION; MUSCULOSKELETAL PAIN; MYALGIA; NAUSEA; NORMAL HUMAN; OPEN STUDY; PARALLEL DESIGN; PARESTHESIA; PATIENT COMPLIANCE; PHYSICAL EXAMINATION; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; PYURIA; SIDE EFFECT; STEADY STATE; SYSTOLIC HYPERTENSION; T WAVE INVERSION; TACHYCARDIA; UPPER ABDOMINAL PAIN; VITAL SIGN; XEROSTOMIA;

ADULT; AGE FACTORS; AGED; AREA UNDER CURVE; BENZHYDRYL COMPOUNDS; CENTRAL NERVOUS SYSTEM STIMULANTS; HUMANS; MALE; WAKEFULNESS;

EID: 79551526449     PISSN: 1170229X     EISSN: 11791969     Source Type: Journal    
DOI: 10.2165/11586370-000000000-00000     Document Type: Article

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