Mechanisms of reflex bladder activation by pudendal afferents

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 300, Issue 2, 2011, Pages

  Woock, John P ^a   Yoo, Paul B ^a   Grill, Warren M ^a,b  

^a USA   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cat; Micturition; Parasympathetic; Sympathetic

Indexed keywords

CHLORALOSE; PHENTOLAMINE; PROPRANOLOL;

ANIMAL EXPERIMENT; ARTICLE; BLADDER CAPACITY; BLADDER CONTRACTION; CAT; EVOKED RESPONSE; HYPOGASTRIC NERVE; MALE; MICTURITION REFLEX; NONHUMAN; PARASYMPATHETIC INNERVATION; PRIORITY JOURNAL; PUDENDAL NERVE; SENSORY NERVE; SYMPATHETIC INNERVATION;

ADRENERGIC ALPHA-ANTAGONISTS; ADRENERGIC BETA-ANTAGONISTS; AFFERENT PATHWAYS; ANIMALS; AUTONOMIC PATHWAYS; CATS; ELECTRIC STIMULATION; HEXAMETHONIUM; HYPOGASTRIC PLEXUS; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PENIS; PRESSURE; REFLEX; SPINAL CORD INJURIES; SYMPATHETIC NERVOUS SYSTEM; URINARY BLADDER;

EID: 79551520688     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00154.2010     Document Type: Article

References (50)

1. Andersson KE. Pharmacology of lower urinary tract smooth muscles and penile erectile tissues. Pharm Rev 45: 254-308, 1993.
2. Andersson KE. α1-Adrenoceptors and bladder function. Eur Urol 36, Suppl 1: 96-102, 1999.
3. Barrington FJF. The component reflexes of micturition in the cat, parts I and II. Brain 54: 177-188, 1931.
4. Boggs JW, Wenzel BJ, Gustafson KJ, Grill WM. Spinal micturition reflex mediated by afferents in the deep perineal nerve. J Neurophysiol 93: 2688-2697, 2005.
5. Boggs JW, Wenzel BJ, Gustafson KJ, Grill WM. Bladder emptying by intermittent electrical stimulation of the pudendal nerve. J Neural Eng 3: 43-51, 2006.
6. Boggs JW, Wenzel BJ, Gustafson KJ, Grill WM. Frequency-dependent selection of reflexes by pudendal afferents in the cat. J Physiol 577: 115-126, 2006.
7. Coonan EM, Downie JW, Du HJ. Sacral spinal cord neurons responsive to bladder pelvic and perineal inputs in cats. Neurosci Lett 260: 137-140, 1999.
8. Craggs M, McFarlane J. Neuromodulation of the lower urinary tract. Exp Physiol 84: 149-160, 1999.
9. Creed KE. The role of the hypogastric nerve in bladder and urethral activity of the dog. Br J Pharmacol 65: 367-375, 1979.
10. Danuser H, Bemis K, Thor KB. Pharmacological analysis of the noradrenergic control of central sympathetic and somatic reflexes controlling the lower urinary tract in the anesthetized cat. J Pharmacol Exp Ther 274: 820-825, 1995.
11. de Groat WC. Integrative control of the lower urinary tract: preclinical perspective. Br J Pharmacol 147, Suppl 2: S25-S40, 2006.
12. de Groat WC, Nadelhaft I, Milne RJ, Booth AM, Morgan C, Thor K. Organization of the sacral parasympathetic reflex pathways to the urinary bladder and large intestine. J Auton Nerv Syst 3: 135-160, 1981.
13. de Groat WC, Saum WR. Sympathetic inhibition of the urinary bladder and of pelvic ganglionic transmission in the cat. J Physiol 220: 297-314, 1972.
14. 1- adrenoceptors. Eur Urol 36, Suppl 1: 68-73, 1999.
15. Dolan JA, Muenkel HA, Burns MG, Pellegrino SM, Fraser CM, Pietri F, Strosberg AD, Largis EE, Dutia MD, Bloom JD, Bass AS, Tanikella TK, Cobuzzi A, Lai FM, Claus TH. β-3 Adrenoceptor selectivity of the dioxolane dicarboxylate phenethanolamines. J Pharmacol Exp Ther 269: 1000-1006, 1994.
16. Edvardsen P. Nervous control of the urinary bladder in cats. III. Effects of autonomic blocking agents in the intact animal. Acta Physiol Scand 72: 183-193, 1968.
17. Edvardsen P. Nervous control of urinary bladder in cats. IV. Effects of autonomic blocking agents on responses to peripheral nerve stimulation. Acta Physiol Scand 72: 234-247, 1968.
18. Espey MJ, Downie JW, Fine A. Effect of 5-HT receptor and adrenoceptor antagonists on micturition in conscious cats. Eur J Pharmacol 221: 167-170, 1992.
19. Hallerback B, Glise H, Sjoqvist A. Reflex sympathetic inhibition of colonic motility in the cat. Scand J Gastroenterol 22: 141-148, 1987.
20. Hamberger B, Norberg KA. Studies on some systems of adrenergic synaptic terminals in the abdominal ganglia of the cat. Acta Physiol Scand 65: 235-242, 1965.
21. Hoffmann C, Leitz MR, Oberdorf-Maass S, Lohse MJ, Klotz KN. Comparative pharmacology of human β-adrenergic receptor subtypes-characterization of stably transfected receptors in CHO cells. Naunyn Schmiedebergs Arch Pharmacol 369: 151-159, 2004.
22. Honda CN. Visceral and somatic afferent convergence onto neurons near the central canal in the sacral spinal cord of the cat. J Neurophysiol 53: 1059-1078, 1985.
23. Horvath EE, Yoo PB, Amundsen CL, Webster GD, Grill WM. Conditional and continuous electrical stimulation increase cystometric capacity in persons with spinal cord injury. Neurourol Urodyn 9: 401-407, 2010.
24. 2-adrenoceptors in micturition in normal conscious rats. J Urol 156: 1853-1857, 1996.
25. 2- adrenoceptors on bladder activity induced by bladder distension in anaesthetized rat. BJU Int 85: 925-931, 2000.
26. 2-adrenoceptors. Am J Physiol Regul Integr Comp Physiol 258: R44-R50, 1990.
27. Kirkham AP, Shah NC, Knight SL, Shah PJ, Craggs MD. The acute effects of continuous and conditional neuromodulation on the bladder in spinal cord injury. Spinal Cord 39: 420-428, 2001.
28. Koley B, Koley J, Saha JK. The effects of nicotine on spontaneous contractions of cat urinary bladder in situ. Br J Pharmacol 83: 347-355, 1984.
29. Kuo DC, Hisamitsu T, de Groat WC. A sympathetic projection from sacral paravertebral ganglia to the pelvic nerve and to postganglionic nerves on the surface of the urinary bladder and large intestine of the cat. J Comp Neurol 226: 76-86, 1984.
30. Lindström S, Fall M, Carlsson CA, Erlandson BE. The neurophysiological basis of bladder inhibition in response to intravaginal electrical stimulation. J Urol 129: 405-410, 1983.
31. Maggi CA, Santicioli P, Meli A. Sympathetic inhibition of reflex activation of bladder motility during filling at a physiological-like rate in urethane anesthetized rats. Neurourol Urodyn 4: 37-45, 1985.
32. McMahon SB, Morrison JF. Factors that determine the excitability of parasympathetic reflexes to the cat bladder. J Physiol 322: 35-43, 1982.
33. Morita T, Ando M, Kihara K, Oshima H. Species differences in cAMP production and contractile response induced by β-adrenoceptor subtypes in urinary bladder smooth muscle. Neurourol Urodyn 12: 185-190, 1993.
34. Nergårdh A. Characterization of the β-adrenergic receptors in the lower urinary tract of the cat. Scand J Urol Nephrol 11: 211-217, 1977.
35. Nishizawa O, Fukuda T, Matsuzaki A, Moriya I, Satoh S, Tsuchida S. Adrenergic influences on the voiding cycle in the decerebrated dog. Neurourol Urodyn 5: 505-513, 1986.
36. Peng CW, Chen JJ, Cheng CL, Grill WM. Role of pudendal afferents in voiding efficiency in the rat. Am J Physiol Regul Integr Comp Physiol 294: R660-R672, 2008.
37. Poirier M, Riffaud JP, Lacolle JY, Dupont C. Effects of five α-blockers on the hypogastric nerve stimulation of the canine lower urinary tract. J Urol 140: 165-167, 1988.
38. Reitz A, Schmid DM, Curt A, Knapp PA, Schurch B. Afferent fibers of the pudendal nerve modulate sympathetic neurons controlling the bladder neck. Neurourol Urodyn 22: 597-601, 2003.
39. Rudy D, Downie J, McAndrew J. α-Chloralose alters autonomic reflex function of the lower urinary tract. Am J Physiol Regul Integr Comp Physiol 261: R1560-R1567, 1991.
40. Shimamura M, Yamauchi T, Aoki M. Effects of chloralose anesthesia on spinal reflexes. Jpn J Physiol 18: 788-797, 1968.
41. Tai C, Shen B, Wang J, Chancellor MB, Roppolo JR, de Groat WC. Inhibitory and excitatory perigenital-to-bladder spinal reflexes in the cat. Am J Physiol Renal Physiol 294: F591-F602, 2008.
42. Tai C, Smerin SE, de Groat WC, Roppolo JR. Pudendal-to-bladder reflex in chronic spinal-cord-injured cats. Exp Neurol 197: 225-234, 2006.
43. Ukimura O. Effects of intravesically administered anticholinergics, β-adrenergic stimulant and α-adrenergic blocker on bladder function in unanesthetized rats. Tohoku J Exp Med 170: 251-260, 1993.
44. Wheeler JS, Walter JS, Zaszczurynski PJ. Bladder inhibition by penile nerve stimulation in spinal cord injury patients. J Urol 147: 100-103, 1993.
45. Woock JP, Yoo PB, Grill WM. Activation and inhibition of the micturition reflex by penile afferents in the cat. Am J Physiol Regul Integr Comp Physiol 294: R1880-R1889, 2008.
46. Woock JP, Yoo PB, Grill WM. Intraurethral stimulation evokes bladder responses via 2 distinct reflex pathways. J Urol 182: 366-373, 2009.
47. 3-adrenergic receptor agonist CL-316243 on experimental bladder hyperreflexia and detrusor instability in the rat. J Urol 166: 1142-1147, 2001.
48. Yoo PB, Klein SM, Grafstein NH, Horvath EE, Amundsen CL, Webster GD, Grill WM. Pudendal nerve stimulation evokes reflex bladder contractions in persons with chronic spinal cord injury. Neurourol Urodyn 26: 1020-1023, 2007.
49. Yoo PB, Woock JP, Grill WM. Bladder activation by selective stimulation of pudendal nerve afferents in the cat. Exp Neurol 212: 218-225, 2008.
50. Yoshiyama M, de Groat WC. Effect of bilateral hypogastric nerve transection on voiding dysfunction in rats with spinal cord injury. Exp Neurol 175: 191-197, 2002.