Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs

American Journal of Respiratory Cell and Molecular Biology

Volumn 44, Issue 2, 2011, Pages 238-243

  Guo, Jin P ^a   Brummet, Mary E ^a   Myers, Allen C ^a   Na, Ho Jeong ^a   Rowland, Elizabeth ^a   Schnaar, Ronald L ^a   Zheng, Tao ^a   Zhu, Zhou ^a   Bochner, Bruce S ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Eosinophil; Glycan ligand; Lung epithelium; Sialic acid; Sialyltransferase

Indexed keywords

GALACTOSE; GLYCAN; GLYCOPROTEIN; HYBRID PROTEIN; LECTIN; PROTEINASE K; SIALIC ACID; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN F; SIALIDASE; SIALYL LEWIS X ANTIGEN; SIALYLTRANSFERASE; SULFOTRANSFERASE; SULFOTRANSFERASE KERATIN SULFATE GALACTOSE 6 O SULFOTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; EOSINOPHIL; LIVER; LUNG; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RESPIRATORY EPITHELIUM; SPLEEN;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; BASE SEQUENCE; DNA PRIMERS; FEMALE; LIGANDS; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYSACCHARIDES; RECOMBINANT FUSION PROTEINS; RESPIRATORY MUCOSA; RNA, MESSENGER; SIALYLTRANSFERASES; SULFOTRANSFERASES;

MURINAE;

EID: 79551505868     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2010-0007OC     Document Type: Article

References (31)

1. Kikly KK, Bochner BS, Freeman S, Tan KB, Gallagher KT, D'Alessio K, Holmes SD, Abrahamson J, Hopson CB, Fischer EI, et al. Identification of SAF-2, a novel Siglec expressed on eosinophils, mast cells and basophils. J Allergy Clin Immunol 2000;105:1093-1100.
2. Floyd H, Ni J, Cornish AL, Zeng Z, Liu D, Carter KC, Steel J, Crocker PR. Siglec-8: a novel eosinophil-specific member of the immunoglobulin superfamily. J Biol Chem 2000;275:861-866.
3. Varki A, Angata T. Siglecs: the major sub-family of I-type lectins. Glycobiology 2006;16:1R-27R.
4. Crocker PR, Paulson JC, Varki A. Siglecs and their roles in the immune system. Nat Rev Immunol 2007;7:255-266.
5. von Gunten S, Bochner BS. Basic and clinical immunology of Siglecs. Ann N Y Acad Sci 2008;1143:61-82.
6. Bochner BS. Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors. Clin Exp Allergy 2009;39:317-324.
7. Tateno H, Crocker PR, Paulson JC. Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6′-sulfo-Sialyl Lewis X as a preferred glycan ligand. Glycobiology 2005;15:1125-1135.
8. Aizawa H, Zimmermann N, Carrigan PE, Lee JJ, Rothenberg ME, Bochner BS. Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G). Genomics 2003;82:521-530.
9. Angata T, Hingorani R, Varki NM, Varki A. Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters. J Biol Chem 2001;276:45128-45136.
10. Zhang JQ, Biedermann B, Nitschke L, Crocker PR. The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils. Eur J Immunol 2004;34:1175-1184.
11. Stevens WW, Kim TS, Pujanauski LM, Hao X, Braciale TJ. Detection and quantitation of eosinophils in the murine respiratory tract by flow cytometry. J Immunol Methods 2007;327:63-74.
12. Nutku E, Aizawa H, Hudson SA, Bochner BS. Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis. Blood 2003;101:5014-5020.
13. Nutku E, Hudson SA, Bochner BS. Mechanism of Siglec-8-induced human eosinophil apoptosis: role of caspases and mitochondrial injury. Biochem Biophys Res Commun 2005;336:918-924.
14. von Gunten S, Vogel M, Schaub A, Stadler BM, Miescher S, Crocker PR, Simon HU. Intravenous immunoglobulin preparations contain anti-Siglec-8 autoantibodies. J Allergy Clin Immunol 2007;119:1005-1011.
15. Nutku-Bilir E, Hudson SA, Bochner BS. Interleukin-5 priming of human eosinophils alters Siglec-8 mediated apoptosis pathways. Am J Respir Cell Mol Biol 2008;38:121-124.
16. Zimmermann N, McBride ML, Yamada Y, Hudson SA, Jones C, Cromie KD, Crocker PR, Rothenberg ME, Bochner BS. Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils. Allergy 2008;63:1156-1163.
17. Zhang M, Angata T, Cho JY, Miller M, Broide DH, Varki A. Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils. Blood 2007;109:4280-4287.
18. Song DJ, Cho JY, Miller M, Strangman W, Zhang M, Varki A, Broide DH. Anti-Siglec-F antibody inhibits oral egg allergen induced intestinal eosinophilic inflammation in a mouse model. Clin Immunol 2009;131:157-169.
19. Song DJ, Cho JY, Lee SY, Miller M, Rosenthal P, Soroosh P, Croft M, Zhang M, Varki A, Broide DH. Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling. J Immunol 2009;183:5333-5341.
20. Bochner BS, Alvarez RA, Mehta P, Bovin NV, Blixt O, White JR, Schnaar RL. Glycan array screening reveals a candidate ligand for Siglec-8. J Biol Chem 2005;280:4307-4312.
21. Tateno H, Li H, Schur MJ, Bovin N, Crocker PR, Wakarchuk WW, Paulson JC. Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity. Mol Cell Biol 2007;27:5699-5710.
22. Von Gunten S, Bochner BS. Expression and function of Siglec-8 in human eosinophils, basophils and mast cells. In: Allergy frontiers: classification and pathomechanisms. Pawankar R, Holgate S, Rosenwasser LJ, editors. Tokyo: Springer; 2009. pp. 297-313.
23. Hudson SA, Bovin N, Schnaar RL, Crocker PR, Bochner BS. Eosinophilselective binding and pro-apoptotic effect in vitro of a synthetic Siglec-8 ligand, polymeric 6′-sulfated Sialyl Lewis X. J Pharmacol Exp Ther 2009;330:608-612.
24. Fukuda M, Hiraoka N, Akama TO, Fukuda MN. Carbohydrate-modifying sulfotransferases: structure, function, and pathophysiology. J BiolChem 2001;276:47747-47750.
25. Takashima S, Tachida Y, Nakagawa T, Hamamoto T, Tsuji S. Quantitative analysis of expression of mouse sialyltransferase genes by competitive PCR. Biochem Biophys Res Commun 1999;260:23-27.
26. Ellies LG, Sperandio M, Underhill GH, Yousif J, Smith M, Priatel JJ, Kansas GS, Ley K, Marth JD. Sialyltransferase specificity in selectin ligand formation. Blood 2002;100:3618-3625.
27. Zhu Z, Zheng T, Homer RJ, Kim YK, Chen NY, Cohn L, Hamid Q, Elias JA. Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation. Science 2004;304:1678-1682.
28. Schwarz A, Futerman AH. Determination of the localization of gangliosides using anti-ganglioside antibodies: comparison of fixation methods. J Histochem Cytochem 1997;45:611-618.
29. Fukuta M, Inazawa J, Torii T, Tsuzuki K, Shimada E, Habuchi O. Molecular cloning and characterization of human keratan sulfate Gal-6-sulfotransferase. J Biol Chem 1997;272:32321-32328.
30. Munday J, Kerr S, Ni J, Cornish AL, Zhang JQ, Nicoll G, Floyd H, Mattei MG, Moore P, Liu D, et al. Identification, characterization and leucocyte expression of Siglec-10, a novel human sialic acid-binding receptor. Biochem J 2001;355:489-497.
31. Spiro RG, Yasumoto Y, Bhoyroo V. Characterization of a rat liver Golgi sulphotransferase responsible for the 6-O-sulphation of N-acetylglucosamine residues in beta-linkage to mannose: role in assembly of Sialyl-galactosyl-N- acetylglucosamine 6-sulphate sequence of N-linked oligosaccharides. Biochem J 1996;319:209-216.