Platelet P2Y12 receptor antagonist pharmacokinetics and pharmaco-dynamics: A foundation for distinguishing mechanisms of bleeding and anticipated risk for platelet-directed therapies

Thrombosis and Haemostasis

Volumn 103, Issue 3, 2010, Pages 535-544

  Becker, Richard C ^a   Gurbel, Paul A ^b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SINAI CENTER FOR THROMBOSIS RESEARCH   (United States)

Author keywords

Cangrelor; Clopidogrel; Platelet P2Y12 receptor; Prasugrel; Ticagrelor

Indexed keywords

ABCIXIMAB; AZD 11703072; CANGRELOR; CLOPIDOGREL; PRASUGREL; PURINERGIC P2Y12 RECEPTOR; THIENOPYRIDINE DERIVATIVE; TICAGRELOR; UNCLASSIFIED DRUG; ANTITHROMBOCYTIC AGENT; PURINERGIC P2 RECEPTOR;

ACUTE CORONARY SYNDROME; BINDING AFFINITY; BLEEDING; DRUG MECHANISM; DRUG STRUCTURE; HUMAN; LOADING DRUG DOSE; NONHUMAN; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; PROTEIN BINDING; REVIEW; RISK ASSESSMENT; THROMBOCYTE AGGREGATION; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; THROMBOSIS;

ANIMALS; HEMORRHAGE; HUMANS; PLATELET AGGREGATION INHIBITORS; RECEPTORS, PURINERGIC P2; THROMBOSIS;

EID: 77749289646     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH09-07-0491     Document Type: Review

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