Pulsatile release of biomolecules from polydimethylsiloxane (PDMS) chips with hydrolytically degradable seals

Journal of Controlled Release

Volumn 127, Issue 3, 2008, Pages 280-287

  Intra, Janjira ^a   Glasgow, Justin M ^a   Mai, Hoang Q ^a   Salem, Aliasger K ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Chips; Non viral gene delivery; Oligonucleotides; Plasmid DNA; Poly(lactic acid co glycolic acid) (PLGA); polydimethylsiloxane (PDMS); Pulsatile release; Transfection

Indexed keywords

BIOMOLECULES; DEGRADATION; DNA; OLIGONUCLEOTIDES; ORGANIC ACIDS; POLYMER FILMS;

NON-VIRAL GENE DELIVERY; PLASMID DNA; PULSATILE RELEASE; TRANSFECTION;

POLYDIMETHYLSILOXANE;

CPG OLIGODEOXYNUCLEOTIDE; DIMETICONE; OVALBUMIN; PLASMID DNA; POLYGLACTIN;

ARTICLE; CONTROLLED STUDY; DRUG DEGRADATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PULSATILE DRUG RELEASE; SCANNING ELECTRON MICROSCOPY;

CELL LINE; DIMETHYLPOLYSILOXANES; DNA; HUMANS; HYDROLYSIS; LACTIC ACID; OVALBUMIN; PLASMIDS; POLYGLYCOLIC ACID; SILICONES; TRANSFECTION;

EID: 42049103678     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2008.02.001     Document Type: Article

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