The N-terminal domain of human hemokinin-1 influences functional selectivity property for tachykinin receptor neurokinin-1

Biochemical Pharmacology

Volumn 81, Issue 5, 2011, Pages 661-668

  Mou, Lingyun ^a   Xing, Yanhong ^a   Kong, Ziqing ^a   Zhou, Ying ^a   Chen, Zongyao ^a   Wang, Rui ^a,b  

^a LANZHOU UNIVERSITY   (China)

^b HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

ERK1 2; Functional selectivity; Hemokinin 1; Neurokinin 1 receptor; NF B

Indexed keywords

ADENYLATE CYCLASE; HUMAN HEMOKININ 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR AGONIST; TACHYKININ; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM; CHO CELLS; CRICETINAE; CRICETULUS; ENDOCYTOSIS; HUMANS; INTRACELLULAR SPACE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NEUROKININ-1; STRUCTURE-ACTIVITY RELATIONSHIP; TACHYKININS;

EID: 79551483416     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.12.007     Document Type: Article

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