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Volumn 8, Issue 2, 2011, Pages 419-426

Post-Translational Inactivation of Endothelial Nitric Oxide Synthase in the Transgenic Sickle Cell Mouse Penis

Author keywords

Caveolin 1; ENOS Phosphorylation; HSP90; Priapism

Indexed keywords

ARGININE DERIVATIVE; CALCIUM; CAVEOLIN 1; CITRULLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HEAT SHOCK PROTEIN 90; NITRIC OXIDE SYNTHASE; PROTEIN KINASE B;

EID: 79551480482     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2010.02123.x     Document Type: Article
Times cited : (21)

References (45)
  • 1
    • 69549107429 scopus 로고    scopus 로고
    • Vasculopathy in sickle cell disease: Biology, pathophysiology, genetics, translational medicine, and new research directions
    • Kato GJ, Hebbel RP, Steinberg MH, Gladwin MT. Vasculopathy in sickle cell disease: Biology, pathophysiology, genetics, translational medicine, and new research directions. Am J Hematol 2009;84:618-25.
    • (2009) Am J Hematol , vol.84 , pp. 618-625
    • Kato, G.J.1    Hebbel, R.P.2    Steinberg, M.H.3    Gladwin, M.T.4
  • 2
    • 34447513984 scopus 로고    scopus 로고
    • Sickle cell disease: Role of reactive oxygen and nitrogen metabolites
    • Wood KC, Granger DN. Sickle cell disease: Role of reactive oxygen and nitrogen metabolites. Clin Exp Pharmacol Physiol 2007;34:926-32.
    • (2007) Clin Exp Pharmacol Physiol , vol.34 , pp. 926-932
    • Wood, K.C.1    Granger, D.N.2
  • 3
    • 0042191729 scopus 로고    scopus 로고
    • Members of the Erectile Dysfunction Guideline Update Panel, Americal Urological Association. American Urological Association Guideline on the management of priapism
    • Montague DK, Jarow J, Broderick GA, Dmochowski RR, Heaton JP, Lue TF, Nehra A, Sharlip ID. Members of the Erectile Dysfunction Guideline Update Panel, Americal Urological Association. American Urological Association Guideline on the management of priapism. J Urol 2003;170:1318-24.
    • (2003) J Urol , vol.170 , pp. 1318-1324
    • Montague, D.K.1    Jarow, J.2    Broderick, G.A.3    Dmochowski, R.R.4    Heaton, J.P.5    Lue, T.F.6    Nehra, A.7    Sharlip, I.D.8
  • 8
  • 9
    • 33750473708 scopus 로고    scopus 로고
    • Feasibility of the use of phosphodiesterase type 5 inhibitors in a pharmacologic prevention program for recurrent priapism
    • Burnett AL, Bivalacqua TJ, Champion HC, Musicki B. Feasibility of the use of phosphodiesterase type 5 inhibitors in a pharmacologic prevention program for recurrent priapism. J Sex Med 2006;3:1077-84.
    • (2006) J Sex Med , vol.3 , pp. 1077-1084
    • Burnett, A.L.1    Bivalacqua, T.J.2    Champion, H.C.3    Musicki, B.4
  • 10
    • 33646849221 scopus 로고    scopus 로고
    • Long-term oral phosphodiesterase 5 inhibitor therapy alleviates recurrent priapism
    • Burnett AL, Bivalacqua TJ, Champion HC, Musicki B. Long-term oral phosphodiesterase 5 inhibitor therapy alleviates recurrent priapism. Urology 2006;67:1043-8.
    • (2006) Urology , vol.67 , pp. 1043-1048
    • Burnett, A.L.1    Bivalacqua, T.J.2    Champion, H.C.3    Musicki, B.4
  • 12
  • 15
    • 33646817106 scopus 로고    scopus 로고
    • Direct interaction of the cell division cycle 37 homolog inhibits endothelial nitric oxide synthase activity
    • Harris MB, Bartoli M, Sood SG, Matts RL, Venema RC. Direct interaction of the cell division cycle 37 homolog inhibits endothelial nitric oxide synthase activity. Circ Res 2006;98:335-41.
    • (2006) Circ Res , vol.98 , pp. 335-341
    • Harris, M.B.1    Bartoli, M.2    Sood, S.G.3    Matts, R.L.4    Venema, R.C.5
  • 16
    • 40349113064 scopus 로고    scopus 로고
    • Low-fat diet and exercise preserve eNOS regulation and endothelial function in the penis of early atherosclerotic pigs: A molecular analysis
    • Musicki B, Liu T, Strong T, Jin L, Laughlin MH, Turk JR, Burnett AL. Low-fat diet and exercise preserve eNOS regulation and endothelial function in the penis of early atherosclerotic pigs: A molecular analysis. J Sex Med 2008;5:552-61.
    • (2008) J Sex Med , vol.5 , pp. 552-561
    • Musicki, B.1    Liu, T.2    Strong, T.3    Jin, L.4    Laughlin, M.H.5    Turk, J.R.6    Burnett, A.L.7
  • 17
    • 77953598967 scopus 로고    scopus 로고
    • Post-translational regulation of endothelial nitric oxide synthase (eNOS) by estrogens in the rat vagina
    • Musicki B, Liu T, Strong TD, Lagoda GA, Bivalacqua TJ, Burnett AL. Post-translational regulation of endothelial nitric oxide synthase (eNOS) by estrogens in the rat vagina. J Sex Med 2010;7:1768-77.
    • (2010) J Sex Med , vol.7 , pp. 1768-1777
    • Musicki, B.1    Liu, T.2    Strong, T.D.3    Lagoda, G.A.4    Bivalacqua, T.J.5    Burnett, A.L.6
  • 18
    • 33847700110 scopus 로고    scopus 로고
    • Overexpression of arginase in the aged mouse penis impairs erectile function and decreases eNOS activity: Influence of in vivo gene therapy of anti-arginase
    • Bivalacqua TJ, Burnett AL, Hellstrom WJ, Champion HC. Overexpression of arginase in the aged mouse penis impairs erectile function and decreases eNOS activity: Influence of in vivo gene therapy of anti-arginase. Am J Physiol Heart Circ Physiol 2007;292:H1340-51.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Bivalacqua, T.J.1    Burnett, A.L.2    Hellstrom, W.J.3    Champion, H.C.4
  • 19
    • 68549118890 scopus 로고    scopus 로고
    • Post-translational modification of constitutive nitric oxide synthase in the penis
    • Musicki B, Ross AE, Champion HC, Burnett AL, Bivalacqua TJ. Post-translational modification of constitutive nitric oxide synthase in the penis. J Androl 2009;30:352-62.
    • (2009) J Androl , vol.30 , pp. 352-362
    • Musicki, B.1    Ross, A.E.2    Champion, H.C.3    Burnett, A.L.4    Bivalacqua, T.J.5
  • 20
    • 34250731849 scopus 로고    scopus 로고
    • Life history of eNOS: Partners and pathways
    • Dudzinski DM, Michel T. Life history of eNOS: Partners and pathways. Cardiovasc Res 2007;75:247-60.
    • (2007) Cardiovasc Res , vol.75 , pp. 247-260
    • Dudzinski, D.M.1    Michel, T.2
  • 21
    • 0034054493 scopus 로고    scopus 로고
    • Enhanced electron flux and reduced calmodulin dissociation may explain "calcium-independent" eNOS activation by phosphorylation
    • McCabe TJ, Fulton D, Roman LJ, Sessa WC. Enhanced electron flux and reduced calmodulin dissociation may explain "calcium-independent" eNOS activation by phosphorylation. J Biol Chem 2000;275:6123-8.
    • (2000) J Biol Chem , vol.275 , pp. 6123-6128
    • McCabe, T.J.1    Fulton, D.2    Roman, L.J.3    Sessa, W.C.4
  • 22
    • 0035980110 scopus 로고    scopus 로고
    • Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells
    • Brouet A, Sonveaux P, Dessy C, Balligand JL, Feron O. Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells. J Biol Chem 2001;276:32663-9.
    • (2001) J Biol Chem , vol.276 , pp. 32663-32669
    • Brouet, A.1    Sonveaux, P.2    Dessy, C.3    Balligand, J.L.4    Feron, O.5
  • 24
    • 0037013152 scopus 로고    scopus 로고
    • Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release
    • Fontana J, Fulton D, Chen Y, Fairchild TA, McCabe TJ, Fujita N, Tsuruo T, Sessa WC. Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release. Circ Res 2002;90:866-73.
    • (2002) Circ Res , vol.90 , pp. 866-873
    • Fontana, J.1    Fulton, D.2    Chen, Y.3    Fairchild, T.A.4    McCabe, T.J.5    Fujita, N.6    Tsuruo, T.7    Sessa, W.C.8
  • 25
    • 3943054801 scopus 로고    scopus 로고
    • Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation
    • Kupatt C, Dessy C, Hinkel R, Raake P, Daneau G, Bouzin C, Boekstegers P, Feron O. Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation. Arterioscler Thromb Vasc Biol 2004;24:1435-41.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1435-1441
    • Kupatt, C.1    Dessy, C.2    Hinkel, R.3    Raake, P.4    Daneau, G.5    Bouzin, C.6    Boekstegers, P.7    Feron, O.8
  • 26
    • 0034718540 scopus 로고    scopus 로고
    • Modulation of Akt kinase activity by binding to Hsp90
    • Sato S, Fujita N, Tsuruo T. Modulation of Akt kinase activity by binding to Hsp90. Proc Natl Acad Sci USA 2000;97:10832-7.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10832-10837
    • Sato, S.1    Fujita, N.2    Tsuruo, T.3
  • 27
    • 0043234527 scopus 로고    scopus 로고
    • Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: Calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex
    • Takahashi S, Mendelsohn ME. Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: Calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex. J Biol Chem 2003;278:30821-7.
    • (2003) J Biol Chem , vol.278 , pp. 30821-30827
    • Takahashi, S.1    Mendelsohn, M.E.2
  • 29
    • 0037465731 scopus 로고    scopus 로고
    • L-4F, an apolipoprotein A-1 mimetic, restores nitric oxide and superoxide anion balance in low-density lipoprotein-treated endothelial cells
    • Ou Z, Ou J, Ackerman AW, Oldham KT, Pritchard KA Jr. L-4F, an apolipoprotein A-1 mimetic, restores nitric oxide and superoxide anion balance in low-density lipoprotein-treated endothelial cells. Circulation 2003;107:1520-4.
    • (2003) Circulation , vol.107 , pp. 1520-1524
    • Ou, Z.1    Ou, J.2    Ackerman, A.W.3    Oldham, K.T.4    Pritchard Jr, K.A.5
  • 32
    • 1542782162 scopus 로고    scopus 로고
    • Chaperone-dependent regulation of endothelial nitric-oxide synthase intracellular trafficking by the co-chaperone/ubiquitin ligase CHIP
    • Jiang J, Cyr D, Babbitt RW, Sessa WC, Patterson C. Chaperone-dependent regulation of endothelial nitric-oxide synthase intracellular trafficking by the co-chaperone/ubiquitin ligase CHIP. J Biol Chem 2003;278:49332-41.
    • (2003) J Biol Chem , vol.278 , pp. 49332-49341
    • Jiang, J.1    Cyr, D.2    Babbitt, R.W.3    Sessa, W.C.4    Patterson, C.5
  • 35
    • 0035844241 scopus 로고    scopus 로고
    • Reciprocal phosphorylation and regulation of endothelial nitric oxide-synthase in response to bradykinin stimulation
    • Harris MB, Ju H, Venema VJ, Liang H, Zou R, Michell BJ, Chen ZP, Kemp BE, Venema RC. Reciprocal phosphorylation and regulation of endothelial nitric oxide-synthase in response to bradykinin stimulation. J Biol Chem 2001;276:16587-91.
    • (2001) J Biol Chem , vol.276 , pp. 16587-16591
    • Harris, M.B.1    Ju, H.2    Venema, V.J.3    Liang, H.4    Zou, R.5    Michell, B.J.6    Chen, Z.P.7    Kemp, B.E.8    Venema, R.C.9
  • 36
    • 0035947574 scopus 로고    scopus 로고
    • Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and cAMP-dependent protein kinase
    • Michell BJ, Chen Z, Tiganis T, Stapleton D, Katsis F, Power DA, Sim AT, Kemp BE. Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and cAMP-dependent protein kinase. J Biol Chem 2001;276:17625-8.
    • (2001) J Biol Chem , vol.276 , pp. 17625-17628
    • Michell, B.J.1    Chen, Z.2    Tiganis, T.3    Stapleton, D.4    Katsis, F.5    Power, D.A.6    Sim, A.T.7    Kemp, B.E.8
  • 38
    • 0037207099 scopus 로고    scopus 로고
    • Site-specific dephosphorylation of endothelial nitric oxide synthase by protein phosphatase 2A: Evidence for crosstalk between phosphorylation sites
    • Greif DM, Kou R, Michel T. Site-specific dephosphorylation of endothelial nitric oxide synthase by protein phosphatase 2A: Evidence for crosstalk between phosphorylation sites. Biochemistry 2002;41:15845-53.
    • (2002) Biochemistry , vol.41 , pp. 15845-15853
    • Greif, D.M.1    Kou, R.2    Michel, T.3
  • 39
    • 0033554044 scopus 로고    scopus 로고
    • Heat shock proteins 70 and 90 increase calcineurin activity in vitro through calmodulin-dependent and independent mechanisms
    • Someren JS, Faber LE, Klein JD, Tumlin JA. Heat shock proteins 70 and 90 increase calcineurin activity in vitro through calmodulin-dependent and independent mechanisms. Biochem Biophys Res Commun 1999;260:619-25.
    • (1999) Biochem Biophys Res Commun , vol.260 , pp. 619-625
    • Someren, J.S.1    Faber, L.E.2    Klein, J.D.3    Tumlin, J.A.4
  • 40
    • 77952891002 scopus 로고    scopus 로고
    • The regulation of endothelial nitric oxide synthase by caveolin: A paradigm validated in vivo and shared by the "endothelium-derived hyperpolarizing factor"
    • Dessy C, Feron O, Balligand JL. The regulation of endothelial nitric oxide synthase by caveolin: A paradigm validated in vivo and shared by the "endothelium-derived hyperpolarizing factor". Pflugers Arch 2010;459:817-27.
    • (2010) Pflugers Arch , vol.459 , pp. 817-827
    • Dessy, C.1    Feron, O.2    Balligand, J.L.3
  • 41
    • 0030853953 scopus 로고    scopus 로고
    • Direct interaction of endothelial nitric-oxide synthase and caveolin-1 inhibits synthase activity
    • Ju H, Zou R, Venema VJ, Venema RC. Direct interaction of endothelial nitric-oxide synthase and caveolin-1 inhibits synthase activity. J Biol Chem 1997;272:18522-5.
    • (1997) J Biol Chem , vol.272 , pp. 18522-18525
    • Ju, H.1    Zou, R.2    Venema, V.J.3    Venema, R.C.4
  • 42
    • 0029787241 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells
    • Feron O, Belhassen L, Kobzik L, Smith TW, Kelly RA, Michel T. Endothelial nitric oxide synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells. J Biol Chem 1996;271:22810-4.
    • (1996) J Biol Chem , vol.271 , pp. 22810-22814
    • Feron, O.1    Belhassen, L.2    Kobzik, L.3    Smith, T.W.4    Kelly, R.A.5    Michel, T.6
  • 43
    • 0039397709 scopus 로고    scopus 로고
    • Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the NOS caveolin binding domain in vivo
    • Garcia-Cardena G, Martasek P, Masters BS, Skidd PM, Couet J, Li S, Lisanti MP, Sessa WC. Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the NOS caveolin binding domain in vivo. J Biol Chem 1997;272:25437-40.
    • (1997) J Biol Chem , vol.272 , pp. 25437-25440
    • Garcia-Cardena, G.1    Martasek, P.2    Masters, B.S.3    Skidd, P.M.4    Couet, J.5    Li, S.6    Lisanti, M.P.7    Sessa, W.C.8
  • 44
    • 0032488818 scopus 로고    scopus 로고
    • The endothelial nitric-oxide synthase-caveolin regulatory cycle
    • Feron O, Saldana F, Michel JB, Michel T. The endothelial nitric-oxide synthase-caveolin regulatory cycle. J Biol Chem 1998;273:3125-8.
    • (1998) J Biol Chem , vol.273 , pp. 3125-3128
    • Feron, O.1    Saldana, F.2    Michel, J.B.3    Michel, T.4
  • 45
    • 34247369430 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase keeps erection regulatory function balance in the penis
    • Bivalacqua TJ, Liu T, Musicki B, Champion HC, Burnett AL. Endothelial nitric oxide synthase keeps erection regulatory function balance in the penis. Eur Urol 2007;51:1732-40.
    • (2007) Eur Urol , vol.51 , pp. 1732-1740
    • Bivalacqua, T.J.1    Liu, T.2    Musicki, B.3    Champion, H.C.4    Burnett, A.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.