Protecting the heritable genome: DNA damage response mechanisms in spermatogonial stem cells

DNA Repair

Volumn 10, Issue 2, 2011, Pages 159-168

  Rübe, Claudia E ^a   Zhang, Sheng ^a   Miebach, Nadine ^a   Fricke, Andreas ^a   Rübe, Christian ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

DNA damage response; DNA double strand breaks; Ionizing irradiation; Spermatogonial stem cells; Stem cell niche

Indexed keywords

ATM PROTEIN; BIOLOGICAL MARKER; CASPASE 3; DOUBLE STRANDED DNA; HISTONE H2AX; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE REGULATION; CELL DEATH; CELL DIFFERENTIATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; GENOME ANALYSIS; HERITABILITY; HETEROCHROMATIN; MALE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOMATIC CELL; SPERMATOGONIAL STEM CELL; SPERMATOGONIUM; TESTIS; WHOLE BODY RADIATION;

ANIMALS; APOPTOSIS; CASPASE 3; CELL CYCLE PROTEINS; CHROMATIN; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; GENES, CDC; GENOME; GENOMIC INSTABILITY; HISTONES; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED C57BL; MICE, SCID; NUCLEAR PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN-SERINE-THREONINE KINASES; SPERMATOGONIA; STEM CELLS; TUMOR SUPPRESSOR PROTEINS; WHOLE-BODY IRRADIATION;

MUS;

EID: 79451474060     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2010.10.007     Document Type: Article

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