Differential inotropic effects of endothelin-1, angiotensin II, and phenylephrine induced by crosstalk with cAMP-mediated signaling process in dog ventricular myocardium

Journal of Pharmacological Sciences

Volumn 96, Issue 2, 2004, Pages 199-207

  Chu, Li ^a,b   Norota, Ikuo ^a   Yomogida, Shin Ichi ^a   Ishii, Kuniaki ^a   Endoh, Masao ^a  

^a YAMAGATA UNIVERSITY   (Japan)

^b HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Bay k 8644; cAMP; Dog ventricular myocardium; Gq protein coupled receptor; Inotropic effect

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; ANGIOTENSIN; CALCIUM CHANNEL L TYPE; CALCIUM ION; CYCLIC AMP; DIHYDROOUABAIN; ENDOTHELIN 1; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; ISOBUTYLMETHYLXANTHINE; PENTOBARBITAL; PHENYLEPHRINE; PHOSPHATIDYLINOSITIDE; PRAZOSIN;

ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; DOG; FEMALE; HEART MUSCLE; HEART VENTRICLE WALL; HYDROLYSIS; INOTROPISM; MALE; MOLECULAR INTERACTION; NONHUMAN; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

EID: 7944235463     PISSN: 13478613     EISSN: None     Source Type: Journal    
DOI: 10.1254/jphs.FP0040412     Document Type: Article

References (33)

1. 1 adrenergic stimulation of 1,4,5-inositol trisphosphate formation in ventricular myocytes. J Pharmacol Exp Ther. 1989;250:1141-1148.
2. q family. J Biol Chem. 1992;267:25798-25802.
3. Endoh M. The role of phosphoinositide hydrolysis in the receptor-mediated inotropic response of the heart. Asia Pacific J Pharmacol. 1997;12:S11-S13.
4. 1-adrenoceptors that regulate contractile function: subtypes and subcellular signal transduction mechanisms. Neurochem Res. 1996;21:217-229.
5. Ishihata A, Endoh M. Species-related differences in inotropic effects of angiotensin II in mammalian ventricular muscle: receptors, subtypes and phosphoinositide hydrolysis. Br J Pharmacol. 1995;114:447-153.
6. Takanashi M, Endoh M. Characterization of the positive inotropic effect of endothelin on mammalian ventricular myocardium. Am J Physiol. 1991;261:H611-H619.
7. Zhu Y, Yang HT, Endoh M. Negative chronotropic and inotropic effects of endothelin isopeptides in mammalian cardiac muscle. Am J Physiol. 1997;273:H119-H127.
8. Chu L, Endoh M. Biphasic inotropic response to endothelin-t in the presence of various concentrations of norepinephrine in dog ventricular myocardium. J Cardiovasc Pharmacol. 2000;36 Suppl 2:S9-S14.
9. 2+ signaling in contractile regulation induced by crosstalk between endothelin-1 and norepinephrine in dog ventricular myocardium. Circ Res. 2003;92:1024-1032.
10. 1-adrenoceptors mediate positive inotropic effect and changes in phosphatidylinositol metabolism: species differences in receptor distribution and the intracellular coupling process in mammalian ventricular myocardium. Circ Res. 1991;68:1179-1190.
11. Yang HT, Zhu Y, Endoh M. Species-dependent differences in I inotropic effects and phosphoinositide hydrolysis induced by endothelin-3 in mammalian ventricular myocardium. Br J Pharmacol. 1997;120:1497-1504.
12. Paiva TB, Aboulafia J, Nouailhetas VL, Paiva AC. Tachyphylaxis and angiotensin receptors. Gen Pharmacol. 1976;7:185-188.
13. Stewart JM, Freer RJ, Rezende L, Pena C, Matsueda GR. A pharmacological study of the angiotensin receptor and tachyphylaxis in smooth muscle. Gen Pharmacol. 1976;7:177-183.
14. Motta SC, Poletti EF, Souza SE, Correa SA, Jubilut GN, Paiva AC. et al. Tachyphylactic properties of angiotensin II analogs with bulky and hydrophobic substituents at the N-terminus. J Pept Res. 2003;62:227-232.
15. 2+ current in dog ventricular myocytes. J Cardiovasc Pharmacol. 2000;36:344-350.
16. Hilal-Dandan R, Urasawa K, Brunton LL. Endothelin inhibits adenylate cyclase and stimulates phosphoinositide hydrolysis in adult cardiac myocytes. J Biol Chem. 1992;267:10620-10624.
17. A-receptors couple to inositol phosphate formation and inhibition of adenylate cyclase in human right atrium. J Cardiovasc Pharmacol. 1994;23:344-347.
18. A receptors in guinea pig atria. Circ Res. 1995;76:284-292.
19. Jones LG. Inhibition of cyclic AMP accumulation by endothelin is pertussis toxin sensitive and calcium independent in isolated adult feline cardiac myocytes. Life Sci. 1996;58:115-123.
20. 1 protein in cultured rat heart cells. Am J Physiol. 1988;255:C51-C59.
21. Anand-Srivastava MB. Angiotensin II receptors negatively coupled to adenylate cyclase in rat myocardial sarcolamma, Involvement of inhibitory guanine nucleotide regulatory protein. Biochem Pharmacol. 1989;38:489-496.
22. 1-adrenoceptor-mediated effect on inositol phosphate production in the heart. Eur J Pharmacol. 1987;134:377-378.
23. Rubanyi GM, Polokoff MA. Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev. 1994;46:325-415.
24. Onishi K, Ohno M, Little WC, Cheng CP. Endogenous endothelin-1 depresses left ventricular systolic and diastolic performance in congestive heart failure. J Pharmacol Exp Ther. 1999;288:1214-1222.
25. Volkmann R, Bokvist K, Wennmalm A. Endothelin has no positive inotropic effect in guinea-pig atria or papillary muscle. Acta Physiol Scand. 1990;138:345-348.
26. Moravec CS, Reynolds EE, Stewart RW, Bond M. Endothelin is a positive inotropic agent in human and rat heart. Biochem Biophys Res Commun 1989;159:14-18.
27. 1-adrenoceptors in adult mouse myocardia: developmental conversion from positive response in the neonate. Br J Pharmacol. 1995;114:673-677.
28. Sekine T, Kusano H, Nishimaru K, Tanaka Y, Tanaka H, Shigenobu K. Developmental conversion of inotropism by endothelin I and angiotensin II from positive to negative in mice. Eur J Pharmacol. 1999;374:411-415.
29. 1-adrenoceptor-mediated negative inotropic response in adult mouse myocardia (abstract). Jpn J Pharmacol. 2000;82 Suppl I:197P.
30. Sakurai K, Norota I, Tanaka H, Kubota I, Tomoike H, Endoh M. Negative inotropic effects of angiotensin II, endothelin-1 and phenylephrine in indo-1 loaded adult mouse ventricular myocytes. Life Sci. 2002;70:1173-1184.
31. Kobayashi M, Furukawa Y, Chiba S. Positive chronotropic and inotropic effects of angiotensin II in the dog heart. Eur J Pharmacol. 1978;50:17-25.
32. Zhang J, Pfaffendorf M, van Zwieten PA. Positive inotropic action of angiotensin II in the pithed rat. Naunyn Schmiedebergs Arch Pharmacol. 1993;347:658-663.
33. Kitayoshi T, Watanabe T, Shimamoto N. Cardiovascular effects of endothelin in dogs: positive inotropic action in vivo. Eur J Pharmacol. 1989;166:519-522.