Endogenous endothelin-1 depresses left ventricular systolic and diastolic performance in congestive heart failure

Journal of Pharmacology and Experimental Therapeutics

Volumn 288, Issue 3, 1999, Pages 1214-1222

  Onishi, Katsuya ^a   Ohno, Michiya ^a   Little, William C ^a   Cheng, Che Ping ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR ANTAGONIST; ENDOTHELIN RECEPTOR ANTAGONIST; METOPROLOL; NITROPRUSSIDE SODIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; DOG; HEART LEFT VENTRICLE CONTRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE FILLING; HEART LEFT VENTRICLE PERFORMANCE; HEART LEFT VENTRICLE PRESSURE; HEART LEFT VENTRICLE RELAXATION; HEART PACING; HEART WORK; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRESSURE VOLUME CURVE; PRIORITY JOURNAL; SYSTEMIC VASCULAR RESISTANCE;

ANIMALS; DOGS; ENDOTHELIN-1; HEART FAILURE, CONGESTIVE; HEMODYNAMIC PROCESSES; NITROPRUSSIDE; RECEPTORS, ENDOTHELIN; TIME FACTORS; VENTRICULAR DYSFUNCTION, LEFT;

EID: 0032984830     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Armstrong PW, Stopps TP, Ford SE and DeBold AJ (1986) Rapid ventricular pacing in the dog: Pathophysiologic studies of heart failure. Circulation 74:1075-1084.
2. B receptors for myocardial contractility and myocardial energy metabolism. J Pharmacol Exp Ther 278:1228-1234.
3. Burchell S, Spinale FG, Tanaka R, Crawford FA and Zile MR (1992) The alterations in the beta-receptor pathway with tachycardia induced cardiomyopathy. J Thorac Cardiovasc Surg 104:1006-1012.
4. 2+ in adult rat cardiac myocytes. Circ Res 66:1143-1155.
5. Cavero PG, Miller WL, Heublein DM, Margulies KB and Burnett JC Jr (1990) Endothelin in experimental congestive heart failure in the anesthetized dog. Am J Physiol 259:F312-F317.
6. Cheng CP, Freeman GL, Santamore WP, Constantinescu MS and Little WC (1990) Effect of loading conditions, contractile state, and heart rate on early diastolic left ventricular filling in conscious dogs. Circ Res 66:814-823.
7. Cheng CP, Noda T, Nozawa T and Little WC (1993) Effect of heart failure on the mechanism of exercise induced augmentation of mitral valve flow. Circ Res 72: 795-806.
8. Cheng CP, Suzuki M, Ohte N, Ohno M, Wang ZM and Little WC (1996) Altered ventricular and myocyte response to angiotensin II in pacing-induced heart failure. Circ Res 78:880-892.
9. Clavell AL, Mattingly MT, Stevens TL, Nir A, Wright RS, Aarhus LL, Heubiein DM and Burnett JC Jr (1996) Angiotensin converting enzyme inhibition modulates endogenous endothelin in chronic canine thoracic inferior vena caval constriction. J Clin Invest 97:1286-1292.
10. Cohn JN (1995) Structural basis for heart failure: Ventricular remodeling and its pharmacological inhibition. Circulation 91:2504-2507.
11. Emori T, Hirata Y, Ohta K, Kanno K, Eguchi S, Imai T, Shichiri M and Marumo F (1991) Cellular mechanism of endothelin-1 release by angiotensin and vasopressin. Hypertension 18:165-170.
12. 2+ modulation. Circ Res 78:302-311.
13. Goto K, Hama H and Kasuya Y (1996) Molecular pharmacology and pathophysiological significance of endothelin. Jpn J Pharmacol 72:261-290.
14. Ishikawa T, Yanagisawa M, Kimura S, Goto K and Masaki T (1988) Positive inotropic action of novel vasoconstrictor peptide endothelin on guinea pig atria. Am J Physiol 255:H970-H973.
15. Ishikawa Y and Homcy CJ (1997) The adenylyl cyclases as integrators of transmembrane signal transduction. Circ Res 80:297-304.
16. + exchange is impaired in cardiac hypertrophy. J Clin Invest 99:125-135.
17. max" to pressure-volume relations: A broader view. Circulation 77:1203-1212.
18. Kiowski W, Sutsch G, Hunziker P, Muller P, Kim J, Oechslin E, Schmitt R, Jones R and Bertel O (1995) Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure. Lancet 346:732-736.
19. i, and contraction in ventricular myocytes. Am J Physiol 265:H793-H800.
20. Kono A, Maughan WL, Sunagawa K, Hamilton K, Sagawa K and Weisfeldt ML (1984) The use of left ventricular end-ejection pressure and peak pressure in the estimation of the end-systolic pressure-volume relationship. Circulation 70:1057-1065.
21. Lenfant C (1994) Report of the Task Force on Research in Heart Failure. Circulation 90:1118-1123.
22. Lerman A, Hildebrand FH Jr, Aarhus LL and Burnett JC (1991) Endothelin has biologic actions at pathophysiologic concentration. Circulation 83:1808-1814.
23. Li K and Rouleau JL (1996) Altered responsiveness to endothelin-1 of myocardium from pacing-induced heart failure model in the dog. Cardiovasc Drugs Ther 10: 107-112.
24. Little WC, Cheng CP, Mumma M, Igarashi Y, Vinten-Johansen J and Johnston WE (1989) Comparison of measures of left ventricular contractile performance from pressure-volume loops in conscious dogs. Circulation 80:1378-1387.
25. Loffler BM, Roux S, Kalina B, Clozel M and Clozel JP (1993) Influence of congestive heart failure on endothelin levels and receptors in rabbits. J Mol Cell Cardiol 25:407-416.
26. Luscher TF, Bock HA, Yang Z and Diederich D (1991) Endothelium-derived relaxing and contracting factors: Perspectives in nephrology. Kidney Int 39:575-590.
27. Margulies KB, Hildebrand FL Jr, Lerman A, Perrella MA and Burnett JC Jr (1990) Increased endothelin in experimental heart failure. Circulation 82:2226-2230.
28. Masaki T, Kimura S, Yanagisawa M and Goto K (1991) Molecular and cellular mechanism of endothelin regulation: Implications for vascular function. Circulation 84:1457-1468.
29. McMurray JJ, Ray SG, Abdullah I, Dargie HJ and Morton JJ (1992) Plasma endothelin in chronic heart failure. Circulation 85:1374-1379.
30. Miller WL, Redfield MM and Burnett JC Jr (1989) Integrated cardiac, renal, and endocrine actions of endothelin. J Clin Invest 83:317-320.
31. Morgan HE (1993) Cellular aspects of cardiac failure. Circulation 87(Suppl i.v.): i.v.-4-i.v.-6.
32. Neubauer S, Ertl G, Haas U, Pulzer F and Kochsiek K (1990) Effects of endothelin-1 in isolated perfused rat heart. J Cardiovasc Pharmacol 16:1-8.
33. O'Brien PJ, Ianuzzo CD, Moe GW, Stopps TP and Armstrong PW (1989) Rapid ventricular pacing of dogs to heart failure: Biochemical and physiological studies. Can J Physiol Pharmacol 68:34-39.
34. Prasad MR and Jones RM (1992) Enhanced membrane protein kinase C activity in myocardial ischemia. Basic Res Cardiol 87:19-26.
35. Rodeheffer RJ, Lerman A, Heublein DM and Burnett JC Jr (1992) Increased plasma concentrations of endothelin in congestive heart failure in humans. Mayo Clin Proc 67:719-723.
36. 2+ accumulation in cardiac sarcoplasmic reticulum. J Biol Chem 265:4302-4308.
37. Sakai S, Miyauchi T, Sakurai T, Kasuya Y, Ihara M, Yamaguchi I, Goto K and Sugishita Y (1996) Endogenous endothelin-1 participates in the maintenance of cardiac function in rats with congestive heart failure: Marked increase in endothelin-1 production in the failing heart. Circulation 93:1214-1222.
38. B receptors mediate contraction to endothelin-1 in human blood vessels. Circulation 89:1203-1208.
39. Shimoyama H, Sabbah HN, Borzak S, Tanimura M, Shevlyagin S, Scicli G and Goldstein S (1996) Short-term hemodynamic effects of endothelin receptor blockade in dogs with chronic heart failure. Circulation 94:779-784.
40. Spinale FG, Tempel GE, Mukherjee R, Eble DM, Brown R, Vacchiano C and Zile MR (1994) Cellular and molecular changes in the beta-adrenergic receptor system with supraventricular tachycardia induced cardiomyopathy. Cardiovasc Res 28:1243-1250.
41. Spinale FG, Walker JD, Mukherjee R, Iannini JP, Keever AT and Gallagher KP (1997) Concomitant endothelin receptor subtype-A blockade during the progression of pacing-induced congestive heart failure in rabbits. Circulation 95:1918-1929.
42. Suzuki M, Ohte N, Wang ZM, Williams DL Jr, Little WC and Cheng CP (1998) Altered inotropic response of endothelin-1 in cardiomyocytes from rats with isoproterenol-induced cardiomyopathy. Cardiovasc Res 39:589-599.
43. Teerlink JR, Loffler BM, Hess P, Maire JP, Clozel M and Clozel JP (1994) Role of endothelin in the maintenance of blood pressure in conscious rats with chronic heart failure: Acute effects of the endothelin receptor antagonist Ro 47-0203 (Bosentan). Circulation 90:2510-2518.
44. Thomas PB, Lin ECK, Webb ML, Mukherjee R and Spinale FG (1996) Evidence of a endothelin-1 autocrine loop in cardiac myocytes: Relation to contractile function with congestive heart failure (Abstract). J Am Coll Cardiol 27:56A.
45. 2+ transients in neonatal and adult rat cardiomyocytes by angiotensin II and endothelin-1. Am J Physiol 270:H857-H868.
46. Watanabe T, Kusumoto K, Kitayoshi T and Shimamoto N (1989) Positive inotropic and vasoconstrictive effects of endothelin-1 in in vivo and in vitro experiments: Characteristics and the role of L-type calcium channels. J Cardiovasc Pharmacol 13:S108-S111.
47. Wei CM, Lerman A, Rodeheffer RJ, McGregor CGA, Brandt RR, Wright S, Heublein DM, Kao PC, Edwards WD and Burnett JC Jr (1994) Endothelin in human congestive heart failure. Circulation 89:1580-1586.
48. Williams DL Jr, Murphy KL, Nolan NA, O'Brien JA, Pettibone DJ, Kivlighn SD, Krause SM, Lis EV Jr, Zingaro GL, Gabel RA, Clayton FC, Siegl PKS, Zhang K, Naue J, Vyas K, Walsh TF, Fitch KJ, Chakravarty PK, Greenlee WJ and Clineschmidt BV (1995a) Pharmacology of L-754,142, a highly potent, orally active, nonpeptidyl endothelin antagonist. J Pharmacol Exp Ther 275:1518-1526.
49. Williams JF Jr, Bristow MR, Fowler MB, Francis GS, Garson A Jr, Gersh BJ, Hammer DF, Hlatky MA, Lerier CV, Packer M, Pitt B, Ullyot DJ, Wexler LF, Winters WL Jr, Ritchie JL, Cheitlin MD, Eagle KA, Gardner TJ, Gibbons RJ, Lewis RP, O'Rourke RA and Ryan TJ (1995b) Guidelines for the evaluation and management of heart failure: Report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines (Committee on Evaluation and Management of Heart Failure). Circulation 92:2764-2784.
50. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K and Masaki T (1988) A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332:411-415.
51. Yang Z, Richard V, von Segesser L, Bauer E, Stulz P, Turina M and Luscher T (1990) Threshold concentrations of endothelin-1 potentiate contractions to norepinephrine and serotonin in human arteries. Circulation 82:188-195.