Iminium metabolite mechanism for nicotine toxicity and addiction: Oxidative stress and electron transfer

Medical Hypotheses

Volumn 64, Issue 1, 2005, Pages 104-111

  Kovacic, P ^a   Cooksy, A ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; ALPHA TOCOPHEROL; ANTIOXIDANT; BETA CAROTENE; CARCINOGEN; CIGARETTE SMOKE; DNA BASE; EPIGALLOCATECHIN GALLATE; IMINE; NICOTINE; NITROGEN; NITROSAMINE; NITROSONORNICOTINE; NORNICOTINE; REACTIVE OXYGEN METABOLITE; SCAVENGER;

AGITATION; ATHEROGENESIS; CARDIOTOXICITY; CENTRAL NERVOUS SYSTEM; CIGARETTE SMOKING; COMA; CONFUSION; DEMETHYLATION; DIETARY INTAKE; DNA ALKYLATION; DNA DAMAGE; DNA STRAND BREAKAGE; ELECTROCHEMISTRY; ELECTRON TRANSPORT; ESOPHAGUS; FRUIT; HUMAN; HYDROLYSIS; HYPOTHESIS; IN VIVO STUDY; ION TRANSPORT; KIDNEY; LIPID PEROXIDATION; LIVER; LUNG TOXICITY; METABOLISM; METABOLITE; NAUSEA; NEUROMODULATION; NEUROTOXICITY; NITROSATION; NONHUMAN; OVARY; OXIDATION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PANCREAS; PHAGOCYTE; PHYSIOLOGY; PRIORITY JOURNAL; PROTON TRANSPORT; REVIEW; SEIZURE; TESTIS; THEORETICAL STUDY; TOBACCO DEPENDENCE; VEGETABLE;

EID: 7944234974     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2004.03.048     Document Type: Article

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