Postmortem serotonin levels in cerebrospinal and pericardial fluids with regard to the cause of death in medicolegal autopsy

Legal Medicine

Volumn 13, Issue 2, 2011, Pages 75-78

  Quan, Li ^a,b   Ishikawa, Takaki ^a,c   Hara, Junpei ^a,c   Michiue, Tomomi ^a,c   Chen, Jian Hua ^a   Wang, Qi ^a   Zhu, Bao Li ^a,d   Maeda, Hitoshi ^a,c  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SUN YAT SEN UNIVERSITY   (China)

^c Medico legal Consultation   (Japan)

^d CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Cerebrospinal fluid; Forensic pathophysiology; Pericardial fluid; Postmortem biochemistry; Serotonin

Indexed keywords

SEROTONIN;

ARTICLE; AUTOPSY; CAUSE OF DEATH; CEREBROSPINAL FLUID; COLD EXPOSURE; DRUG INTOXICATION; HEAD INJURY; HEART FUNCTION; HEAT STROKE; HUMAN; HYPNOSIS; INTENSIVE CARE; MEDICOLEGAL ASPECT; PERICARDIUM; SEX DIFFERENCE;

ADULT; AGED; AGED, 80 AND OVER; AUTOPSY; BIOLOGICAL MARKERS; CAUSE OF DEATH; FEMALE; FORENSIC PATHOLOGY; HUMANS; MALE; MIDDLE AGED; PERICARDIAL EFFUSION; POSTMORTEM CHANGES; SEROTONIN; YOUNG ADULT;

EID: 79251645102     PISSN: 13446223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.legalmed.2010.11.003     Document Type: Article

References (43)

1. Wang S., Zhang Q.J., Liu J., Wu Z.H., Wang T., Gui Z.H., et al. Unilateral lesion of the nigrostriatal pathway induces an increase of neuronal firing of the midbrain raphe nuclei 5-HT neurons and a decrease of their response to 5-HT(1A) receptor stimulation in the rat. Neuroscience 2009, 159:850-861.
2. Rivera H.M., Oberbeck D.R., Kwon B., Houpt T.A., Eckel L.A. Estradiol increases Pet-1 and serotonin transporter mRNA in the midbrain raphe nuclei of ovariectomized rats. Brain Res 2009, 1259:51-58.
3. Barker J.R., Thomas C.F., Behan M. Serotonergic projections from the caudal raphe nuclei to the hypoglossal nucleus in male and female rats. Respir Physiol Neurobiol 2009, 165:175-184.
4. Stein L., Wise C.D., Belluzzi J.D. Effects of benzodiazepines on central serotonergic mechanisms. Adv Biochem Psychopharmacol 1975, 14:29-44.
5. Meyer M.C., Baldessarini R.J., Goff D.C., Centorrino F. Clinically significant interactions of psychotropic agents with antipsychotic drugs. Drug Saf 1996, 15:333-346.
6. Devlin R.J., Henry J.A. Clinical review: major consequences of illicit drug consumption. Crit Care 2008, 12:202.
7. Truitt E.B. Marihuana vs. alcohol: a pharmacologic comparison. Adv Exp Med Biol 1975, 56:291-309.
8. Corchs F, Nutt DJ, Hood S, Bernik M. Serotonin and sensitivity to trauma-related exposure in selective serotonin reuptake inhibitors-recovered posttraumatic stress disorder. Biol Psychiatry 2009. doi:10.1016/i.biopsych.2009.01.031. doi:10.1016/i.biopsych.2009.01.031.
9. Stein D.J., Ipser J., McAnda N. Pharmacotherapy of posttraumatic stress disorder: a review of meta-analyses and treatment guidelines. CNS Spectr 2009, 14:25-31.
10. Sullivan G.M., Neria Y. Pharmacotherapy in post-traumatic stress disorder: evidence from randomized controlled trials. Curr Opin Investig Drugs 2009, 10:35-45.
11. Hansen M.B., Witte A.B. The role of serotonin in intestinal luminal sensing and secretion. Acta Physiol (Oxf) 2008, 193:311-323.
12. Thor P.J., Krolczyk G., Gil K., Zurowski D., Nowak L. Melatonin and serotonin effects on gastrointestinal motility. J Physiol Pharmacol 2007, 58:97-103.
13. Ge S., White J.G., Haynes C.L. Quantal release of serotonin from platelets. Anal Chem 2009, 81:2935-2943.
14. Mohammad-Zadeh L.F., Moses L., Gwaltney-Brant S.M. Serotonin: a review. J Vet Pharmacol Ther 2008, 31:187-199.
15. Luna A., Villanueva E., Hernandez-Cueto C., Morales I. Study of 5-hydroxytryptamine (serotonin) in pericardial fluid in different causes of death (II). Experimental study of 5-HT levels in two types of shocks (hemorrhagic and septic) in dogs. Z Rechtsmed 1983, 89:227-236.
16. Klemola R., Huttunen P., Laine M., Weckström M., Hirvonen J. Catecholamines in pericardial fluid of normotensive, spontaneously hypertensive and reserpine-treated rats. Acta Physiol Scand 1999, 165:293-297.
17. Stewart R.V., Zumwalt R.E., Hirsch C.S., Kaplan L. Postmortem diagnosis of myocardial disease by enzyme analysis of pericardial fluid. Am J Clin Pathol 1984, 82:411-417.
18. Ramage A.G., Villalón C.M. 5-Hydroxytryptamine and cardiovascular regulation. Trends Pharmacol Sci 2008, 29:472-481.
19. 1A activation counteracts cardiovascular but not hypophagic effects of sibutramine in rats. Obesity 2009, 17:467-473.
20. Mitro P., Mudráková K., Micková H., Dudás J., Kirsch P., Valocik G. Hemodynamic parameters and heart rate variability during a tilt test in relation to gene polymorphism of renin-angiotensin and serotonin system. Pacing Clin Electrophysiol 2008, 31:1571-1580.
21. Ishikawa T., Yoshida C., Michiue T., Perdekamp M.G., Pollak S., Maeda H. Immunohistochemistry of catecholamines in the hypothalamic-pituitary-adrenal system with special regard to fatal hypothermia and hyperthermia. Leg Med 2010, 12:121-127.
22. Nikolin B., Imamović B., Medanhodzić-Vuk S., Sober M. High performance liquid chromatography in pharmaceutical analyses. Bosn J Basic Med Sci 2004, 4:5-9.
23. Fujimori T., Yamanishi Y., Yamatsu K., Tajima T. High performance liquid chromatography (HPLC) determination of endogenous serotonin released from aggregating platelets. J Pharmacol Methods 1982, 7:105-113.
24. Maeda H., Fukita K., Oritani S., Nagai K., Zhu B.L. Evaluation of post-mortem oxymetry in fire victims. Forensic Sci Int 1996, 81:201-209.
25. Maeda H., Fukita K., Oritani S., Ishida K., Zhu B.L. Evaluation of post-mortem oxymetry with reference to the causes of death. Forensic Sci Int 1997, 87:201-210.
26. Oritani S., Zhu B.L., Ishida K., Shimotouge K., Quan L., Fujita M.Q., et al. Automated determination of carboxyhemoglobin contents in autopsy materials using head-space gas chromatography/mass spectrometry. Forensic Sci Int 2000, 113:375-379.
27. Vossen J.A., Buijs M., Liapi E., Eng J., Bluemke D.A., Kamel I.R. Receiver operating characteristic analysis of diffusion-weighted magnetic resonance imaging in differentiating hepatic hemangioma from other hypervascular liver lesions. J Comput Assist Tomogr 2008, 32:750-756.
28. Lee Y.W., Kim H.J., Cho Y.H., Shin H.B., Choi T.Y., Lee Y.K. Application of albumin-adjusted ischemia modified albumin index as an early screening marker for acute coronary syndrome. Clin Chim Acta 2007, 384:24-27.
29. Musshoff F., Menting T., Madea B. Postmortem serotonin (5-HT) concentrations in the cerebrospinal fluid of medicolegal cases. Forensic Sci Int 2004, 142:211-219.
30. Anderson G.M., Mefford I.N., Tolliver T.J., Riddle M.A., Ocame D.M., Leckman J.F., et al. Serotonin in human lumbar cerebrospinal fluid: a reassessment. Life Sci 1990, 46:247-255.
31. Strosberg J., Nasir A., Cragun J., Gardner N., Kvols L. Metastatic carcinoid tumor to the ovary: a clinicopathologic analysis of seventeen cases. Gynecol Oncol 2007, 106:65-68.
32. Taal B.G., Smits M. Developments in diagnosis and treatment of metastatic midgut carcinoid tumors. A review. Minerva Gastroenterol Dietol 2005, 51:335-344.
33. Barbui C., Esposito E., Cipriani A. Selective serotonin reuptake inhibitors and risk of suicide: a systematic review of observational studies. CMAJ 2009, 180:291-297.
34. Ryding E., Lindström M., Träskman-Bendz L. The role of dopamine and serotonin in suicidal behaviour and aggression. Prog Brain Res 2008, 172:307-315.
35. Matthews J.D., Fava M. Risk of suicidality in depression with serotonergic antidepressants. Ann Clin Psychiatry 2000, 12:43-50.
36. Arango V., Underwood M.D., Mann J.J. Serotonin brain circuits involved in major depression and suicide. Prog Brain Res 2002, 136:443-453.
37. Isbister G.K., Buckley N.A., Whyte I.M. Serotonin toxicity: a practical approach to diagnosis and treatment. Med J Aust 2007, 187:361-365.
38. Pilgrim J.L., Gerostamoulos D., Drummer O.H. Review: pharmacogenetic aspects of the effect of cytochrome P450 polymorphisms on serotonergic drug metabolism, response, interactions, and adverse effects. Forensic Sci Med Pathol. 2010, 10.1007/s12024-010-9188-3.
39. Myers R.D. Serotonin and thermoregulation: old and new views. J Physiol 1981, 77:505-513.
40. Okuda C., Saito A., Miyazaki M., Kuriyama K. Alteration of the turnover of dopamine and 5-hydroxytryptamine in rat brain associated with hypothermia. Pharmacol Biochem Behav 1986, 24:79-83.
41. Zhu B.L., Ishikawa T., Michiue T., Li D.R., Zhao D.R., Quan L., et al. Postmortem serum catecholamine levels in relation to the cause of death. Forensic Sci Int 2007, 173:122-129.
42. Wilke N., Janssen H., Fahrenhorst C., Hecker H., Manns M.P., Brabant E.G., et al. Postmortem determination of concentrations of stress hormones in various body fluids-is there a dependency between adrenaline/noradrenaline quotient, cause of death and agony time?. Int J Legal Med 2007, 121:385-394.
43. Ishikawa T., Quan L., Li D.R., Zhao D., Michiue T., Hamel M., et al. Postmortem biochemistry and immunohistochemistry of adrenocorticotropic hormone with special regard to fatal hypothermia. Forensic Sci Int 2008, 179:147-151.