Cumulative responses of muscle protein synthesis are augmented with chronic resistance exercise training

Acta Physiologica

Volumn 201, Issue 3, 2011, Pages 381-389

  Gasier, H G ^a   Riechman, S E ^a   Wiggs, M P ^a   Buentello, A ^a   Previs, S F ^b   Fluckey, J D ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anabolism; Cumulative muscle protein synthesis; Exercise training

Indexed keywords

INITIATION FACTOR 4E; INITIATION FACTOR 4E BINDING PROTEIN 1; MUSCLE PROTEIN; PHENYLALANINE;

ANIMAL EXPERIMENT; ARTICLE; BODY MASS; CONTROLLED STUDY; IMMUNOPRECIPITATION; MALE; NONHUMAN; PLANTARIS MUSCLE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; RESISTANCE TRAINING; RNA TRANSLATION; SOLEUS MUSCLE; WESTERN BLOTTING;

ANIMALS; MALE; MUSCLE PROTEINS; MUSCLE, SKELETAL; PHYSICAL CONDITIONING, ANIMAL; PHYSICAL EXERTION; RATS; RATS, SPRAGUE-DAWLEY; RESISTANCE TRAINING;

EID: 79251635967     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2010.02183.x     Document Type: Article

References (39)

1. Armstrong, R.B. & Phelps, R.O. 1984. Muscle fiber type composition of the rat hindlimb. Am J Anat 171, 259-272.
2. Biolo, G., Maggi, S.P., Williams, B.D., Tipton, K.D. & Wolfe, R.R. 1995. Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humans. Am J Physiol 268, E514-E520.
3. Bolster, D.R., Kimball, S.R. & Jefferson, L.S. 2003a. Translational control mechanisms modulate skeletal muscle gene expression during hypertrophy. Exerc Sport Sci Rev 31, 111-116.
4. Bolster, D.R., Kubica, N., Crozier, S.J., Williamson, D.L., Farrell, P.A., Kimball, S.R. & Jefferson, L.S. 2003b. Immediate response to mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle. J Physiol 553, 213-220.
5. Brunn, G.J., Hudson, C.C., Sekulic, A., Williams, J.M., Hosoi, H., Houghton, P.J., Lawrence, J.C., Jr & Abraham, R.T. 1997. Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin. Science 277, 99-101.
6. Buentello, J.A. & Gatlin, D.M., III. 2001. Plasma citrulline and arginine kinetics in juvenile channel catfish, Ictalurus punctatus, given oral gabaculine. Fish Physiol Biochem 24, 105-112.
7. Chesley, A., MacDougall, J.D., Tarnopolsky, M.A., Atkinson, S.A. & Smith, K. 1992. Changes in human muscle protein synthesis after resistance exercise. J Appl Physiol 73, 1383-1388.
8. 2O to study the influence of feeding on protein synthesis: effect of isotope equilibration in vivo vs. in cell culture. Am J Physiol Endocrinol Metab 288, E1277-E1283.
9. Farrell, P.A., Fedele, M.J., Hernandez, J., Fluckey, J.D., Miller, J.L., Lang, C.H., Vary, T.C., Kimball, S.R. & Jefferson, L.S. 1999a. Hypertrophy of skeletal muscle in diabetic rats in response to chronic resistance exercise. J Appl Physiol 87, 1075-1082.
10. Farrell, P.A., Fedele, M.J., Vary, T.C., Kimball, S.R., Lang, C.H. & Jefferson, L.S. 1999b. Regulation of protein synthesis after acute resistance exercise in diabetic rats. Am J Physiol 276, E721-E727.
11. Fluckey, J.D., Kraemer, W.J. & Farrell, P.A. 1995. Pancreatic islet insulin secretion is increased after resistance exercise in rats. J Appl Physiol 79, 1100-1105.
12. Fluckey, J.D., Vary, T.C., Jefferson, L.S. & Farrell, P.A. 1996. Augmented insulin action on rates of protein synthesis after resistance exercise in rats. Am J Physiol 270, E313-E319.
13. Fluckey, J.D., Pohnert, S.C., Boyd, S.G., Cortright, R.N., Trappe, T.A. & Dohm, G.L. 2000. Insulin simulation of muscle protein synthesis in obese Zucker rats is not via a rapamycin-sensitive pathway. Am J Physiol Endocrinol Metab 279, E182-E187.
14. Fluckey, J.D., Knox, M., Smith, L., Dupont-Versteegden, E.E., Gaddy, D., Tesch, P.A. & Peterson, C.A. 2006. Insulin-facilitated increase of muscle protein synthesis after resistance exercise involves a MAP kinase pathway. Am J Physiol Endocrinol Metab 290, E1205-E1211.
15. Fujita, S., Dreyer, H.C., Drummond, M.J., Glynn, E.L., Volpi, E. & Rasmussen, B.B.. 2008. Essential amino acid and carbohydrate ingestion prior to resistance exercise does not enhance post-exercise muscle protein synthesis. J Appl Physiol 106, 1730-1739.
16. Garlick, P.J., McNurlan, M.A. & Preedy, V.R. 1980. A rapid and convenient technique for measuring the rate of protein synthesis in tissues by injection of [3H]phenylalanine. Biochem J 192, 719-723.
17. 2O and phenylalanine flooding dose to investigate muscle protein synthesis with acute exercise in rats. Am J Physiol Endocrinol Metab 279, E252-E259.
18. 2O to measure skeletal muscle protein synthesis. Nutr Metab (Lond) 7, 31.
19. Gingras, A.C., Gygi, S.P., Raught, B., Polakiewicz, R.D., Abraham, R.T., Hoekstra, M.F., Aebersold, R. & Sonenberg, N. 1999. Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism. Genes Dev 13, 1422-1437.
20. Hernandez, J., Fedele, M.J. & Farrell, P.A. 2000. Time course evaluation of protein synthesis and glucose uptake after acute resistance exercise in rats. J Appl Physiol 88, 1142-1149.
21. Kim, P.L., Staron, R.S. & Phillips, S.M. 2005. Fasted-state skeletal muscle protein synthesis after resistance exercise is altered with training. J Physiol 568, 283-290.
22. Kimball, S.R., Jurasinski, C.V., Lawrence, J.C., Jr & Jefferson, L.S. 1997. Insulin stimulates protein synthesis in skeletal muscle by enhancing the association of eIF-4E and eIF-4G. Am J Physiol 272, C754-C759.
23. Kostyak, J.C., Kimball, S.R., Jefferson, L.S. & Farrell, P.A. 2001. Severe diabetes inhibits resistance exercise-induced increase in eukaryotic initiation factor 2Β activity. J Appl Physiol 91, 79-84.
24. Kubica, N., Bolster, D.R., Farrell, P.A., Kimball, S.R. & Jefferson, L.S. 2005. Resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2Bepsilon mRNA in a mammalian target of rapamycin-dependent manner. J Biol Chem 280, 7570-7580.
25. Mochizuki, K., Oguro, A., Ohtsu, T., Sonenberg, N. & Nakamura, Y. 2005. High affinity RNA for mammalian initiation factor 4E interferes with mRNA-cap binding and inhibits translation. RNA 11, 77-89.
26. Phillips, S.M., Tipton, K.D., Aarsland, A., Wolf, S.E. & Wolfe, R.R. 1997. Mixed muscle protein synthesis and breakdown after resistance exercise in humans. Am J Physiol 273, E99-E107.
27. Phillips, S.M., Tipton, K.D., Ferrando, A.A. & Wolfe, R.R. 1999. Resistance training reduces the acute exercise-induced increase in muscle protein turnover. Am J Physiol 276, E118-E124.
28. Phillips, S.M., Parise, G., Roy, B.D., Tipton, K.D., Wolfe, R.R. & Tamopolsky, M.A. 2002. Resistance-training-induced adaptations in skeletal muscle protein turnover in the fed state. Can J Physiol Pharmacol 80, 1045-1053.
29. 2O: application to patients with end-stage renal disease. Am J Physiol Endocrinol Metab 286, E665-E672.
30. Proud, C.G. 2007. Signalling to translation: how signal transduction pathways control the protein synthetic machinery. Biochem J 403, 217-234.
31. Roux, P.P., Shahbazian, D., Vu, H., Holz, M.K., Cohen, M.S., Taunton, J., Sonenberg, N. & Blenis, J. 2007. RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. J Biol Chem 282, 14056-14064.
32. Smith, P.K., Krohn, R.I., Hermanson, G.T., Mallia, A.K., Gartner, F.H., Provenzano, M.D., Fujimoto, E.K., Goeke, N.M., Olson, B.J. & Klenk, D.C. 1985. Measurement of protein using bicinchoninic acid. Anal Biochem 150, 76-85.
33. Svitkin, Y.V., Herdy, B., Costa-Mattioli, M., Gingras, A.C., Raught, B. & Sonenberg, N. 2005. Eukaryotic translation initiation factor 4E availability controls the switch between cap- dependent and internal ribosomal entry site-mediated translation. Mol Cell Biol 25, 10556-10565.
34. Tang, J.E., Perco, J.G., Moore, D.R., Wilkinson, S.B. & Phillips, S.M. 2008. Resistance training alters the response of fed state mixed muscle protein synthesis in young men. Am J Physiol Regul Integr Comp Physiol 294, R172-R178.
35. Vary, T.C., Siegel, J.H., Tall, B.D., Morris, J.G. & Smith, J.A. 1988. Inhibition of skeletal muscle protein synthesis in septic intra-abdominal abscess. J Trauma 28, 981-988.
36. Westerlind, K.C., Fluckey, J.D., Gordon, S.E., Kraemer, W.J., Farrell, P.A. & Turner, R.T. 1998. Effect of resistance exercise training on cortical and cancellous bone in mature male rats. J Appl Physiol 84, 459-464.
37. Wolfe, R.R. & Chinkes, D.L. 2005. Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis, 2nd edn. John Wiley and Sons, Inc, Hoboken, NJ.
38. Xiao, G.G., Garg, M., Lim, S., Wong, D., Go, V.L. & Lee, W.N. 2008. Determination of protein synthesis in vivo using labeling from deuterated water and analysis of MALDI-TOF spectrum. J Appl Physiol 104, 828-836.
39. Yang, D., Diraison, F., Beylot, M., Brunengraber, D.Z., Samols, M.A., Anderson, V.E. & Brunengraber, H. 1998. Assay of low deuterium enrichment of water by isotopic exchange with [U-13C3]acetone and gas chromatography-mass spectrometry. Anal Biochem 258, 315-321.