Dose-dependent toxic effects of high-dose estrogen on renal and cardiac injury in surgically postmenopausal mice

Life Sciences

Volumn 88, Issue 3-4, 2011, Pages 178-186

  Meng, Xiaomei ^a   Dai, Xiangguo ^a   Liao, Tang Dong ^a   D'Ambrosio, Martin ^a   Wang, Fangfei ^a   Yang, James J ^a   Yang, Xiao Ping ^a  

^a HENRY FORD HOSPITAL   (United States)

Author keywords

Albuminuria; Estrogen dosage; Heart; Hydronephrosis; Kidney

Indexed keywords

CREATININE; ESTRADIOL; ESTROGEN; MARKER; PLACEBO;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASCITES; BLOOD PRESSURE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG MEGADOSE; ESTROGEN BLOOD LEVEL; FEMALE; FLUID RETENTION; GLOMERULOSCLEROSIS; GLOMERULUS; HEART FUNCTION; HEART INJURY; HEART WEIGHT; HEMODYNAMIC PARAMETERS; HEPATOMEGALY; HYDRONEPHROSIS; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY MASS; KIDNEY TUBULE; LIVER WEIGHT; LOW DRUG DOSE; LUNG WEIGHT; MORPHOLOGY; MOUSE; NONHUMAN; OVARIECTOMY; OXIDATIVE STRESS; POSTMENOPAUSE; UTERUS HORN; UTERUS WEIGHT;

ALBUMINURIA; ANIMALS; BLOOD PRESSURE; BLOTTING, WESTERN; CREATININE; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; ESTROGEN REPLACEMENT THERAPY; ESTROGENS; FEMALE; HEART; HEART FUNCTION TESTS; KIDNEY; MICE; ORGAN SIZE; OVARIECTOMY; OXIDATIVE STRESS; POSTMENOPAUSE; UTERUS;

MUS;

EID: 79251614993     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.11.008     Document Type: Article

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