메뉴 건너뛰기




Volumn 201, Issue 3, 2011, Pages 365-372

Resistance exercise enhances mTOR and MAPK signalling in human muscle over that seen at rest after bolus protein ingestion

Author keywords

Amino acids; Intracellular signalling; Muscle hypertrophy

Indexed keywords

ELONGATION FACTOR 2; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MUSCLE PROTEIN; S6 KINASE;

EID: 79251609502     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2010.02187.x     Document Type: Article
Times cited : (97)

References (31)
  • 1
    • 78649242199 scopus 로고    scopus 로고
    • Influence of supplementation with branched-chain amino acids in combination with resistance exercise on p70 kinase phosphorylation in resting and exercising human skeletal muscle
    • Epub ahead of print.
    • Apro, W. & Blomstrand, E. 2010. Influence of supplementation with branched-chain amino acids in combination with resistance exercise on p70 kinase phosphorylation in resting and exercising human skeletal muscle. Acta Physiol (Oxf) Epub ahead of print.
    • (2010) Acta Physiol (Oxf)
    • Apro, W.1    Blomstrand, E.2
  • 2
    • 0032948278 scopus 로고    scopus 로고
    • Phosphorylation of p70(S6k) correlates with increased skeletal muscle mass following resistance exercise
    • Baar, K. & Esser, K. 1999. Phosphorylation of p70(S6k) correlates with increased skeletal muscle mass following resistance exercise. Am J Physiol 276, C120-C127.
    • (1999) Am J Physiol , vol.276
    • Baar, K.1    Esser, K.2
  • 3
    • 0030859081 scopus 로고    scopus 로고
    • An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein
    • Biolo, G., Tipton, K.D., Klein, S. & Wolfe, R.R. 1997. An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein. Am J Physiol 273, E122-E129.
    • (1997) Am J Physiol , vol.273
    • Biolo, G.1    Tipton, K.D.2    Klein, S.3    Wolfe, R.R.4
  • 6
    • 33749351995 scopus 로고    scopus 로고
    • Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle
    • Dreyer, H.C., Fujita, S., Cadenas, J.G., Chinkes, D.L., Volpi, E. & Rasmussen, B.B. 2006. Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle. J Physiol 576, 613-624.
    • (2006) J Physiol , vol.576 , pp. 613-624
    • Dreyer, H.C.1    Fujita, S.2    Cadenas, J.G.3    Chinkes, D.L.4    Volpi, E.5    Rasmussen, B.B.6
  • 9
    • 63849130621 scopus 로고    scopus 로고
    • Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis
    • Drummond, M.J., Fry, C.S., Glynn, E.L., Dreyer, H.C., Dhanani, S., Timmerman, K.L., Volpi, E. & Rasmussen, B.B. 2009. Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis. J Physiol 587, 1535-1546.
    • (2009) J Physiol , vol.587 , pp. 1535-1546
    • Drummond, M.J.1    Fry, C.S.2    Glynn, E.L.3    Dreyer, H.C.4    Dhanani, S.5    Timmerman, K.L.6    Volpi, E.7    Rasmussen, B.B.8
  • 12
    • 51149110733 scopus 로고    scopus 로고
    • Resistance exercise decreases eIF2Bepsilon phosphorylation and potentiates the feeding-induced stimulation of p70S6K1 and rpS6 in young men
    • Glover, E.I., Oates, B.R., Tang, J.E., Moore, D.R., Tarnopolsky, M.A. & Phillips, S.M. 2008. Resistance exercise decreases eIF2Bepsilon phosphorylation and potentiates the feeding-induced stimulation of p70S6K1 and rpS6 in young men. Am J Physiol Regul Integr Comp Physiol 295, R604-R610.
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.295
    • Glover, E.I.1    Oates, B.R.2    Tang, J.E.3    Moore, D.R.4    Tarnopolsky, M.A.5    Phillips, S.M.6
  • 14
    • 34547855551 scopus 로고    scopus 로고
    • Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters
    • Hartman, J.W., Tang, J.E., Wilkinson, S.B., Tarnopolsky, M.A., Lawrence, R.L., Fullerton, A.V. & Phillips, S.M. 2007. Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters. Am J Clin Nutr 86, 373-381.
    • (2007) Am J Clin Nutr , vol.86 , pp. 373-381
    • Hartman, J.W.1    Tang, J.E.2    Wilkinson, S.B.3    Tarnopolsky, M.A.4    Lawrence, R.L.5    Fullerton, A.V.6    Phillips, S.M.7
  • 15
    • 66349104285 scopus 로고    scopus 로고
    • Resistance exercise with whey protein ingestion affects mTOR signaling pathway and myostatin in men
    • Hulmi, J.J., Tannerstedt, J., Selanne, H., Kainulainen, H., Kovanen, V. & Mero, A.A. 2009. Resistance exercise with whey protein ingestion affects mTOR signaling pathway and myostatin in men. J Appl Physiol 106, 1720-1729.
    • (2009) J Appl Physiol , vol.106 , pp. 1720-1729
    • Hulmi, J.J.1    Tannerstedt, J.2    Selanne, H.3    Kainulainen, H.4    Kovanen, V.5    Mero, A.A.6
  • 17
    • 0036720367 scopus 로고    scopus 로고
    • Invited Review: Role of insulin in translational control of protein synthesis in skeletal muscle by amino acids or exercise
    • Kimball, S.R., Farrell, P.A. & Jefferson, L.S. 2002. Invited Review: Role of insulin in translational control of protein synthesis in skeletal muscle by amino acids or exercise. J Appl Physiol 93, 1168-1180.
    • (2002) J Appl Physiol , vol.93 , pp. 1168-1180
    • Kimball, S.R.1    Farrell, P.A.2    Jefferson, L.S.3
  • 18
    • 34548081433 scopus 로고    scopus 로고
    • Protein ingestion further augments S6K1 phosphorylation in skeletal muscle following resistance type exercise in males
    • Koopman, R., Pennings, B., Zorenc, A.H. & van Loon, L.J. 2007. Protein ingestion further augments S6K1 phosphorylation in skeletal muscle following resistance type exercise in males. J Nutr 137, 1880-1886.
    • (2007) J Nutr , vol.137 , pp. 1880-1886
    • Koopman, R.1    Pennings, B.2    Zorenc, A.H.3    van Loon, L.J.4
  • 21
    • 60349086380 scopus 로고    scopus 로고
    • Differential stimulation of myofibrillar and sarcoplasmic protein synthesis with protein ingestion at rest and after resistance exercise
    • Moore, D.R., Tang, J.E., Burd, N.A., Rerecich, T., Tarnopolsky, M.A. & Phillips, S.M. 2009b. Differential stimulation of myofibrillar and sarcoplasmic protein synthesis with protein ingestion at rest and after resistance exercise. J Physiol 587, 897-904.
    • (2009) J Physiol , vol.587 , pp. 897-904
    • Moore, D.R.1    Tang, J.E.2    Burd, N.A.3    Rerecich, T.4    Tarnopolsky, M.A.5    Phillips, S.M.6
  • 22
    • 34347242470 scopus 로고    scopus 로고
    • RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation
    • Roux, P.P., Shahbazian, D., Vu, H., Holz, M.K., Cohen, M.S., Taunton, J., Sonenberg, N. & Blenis, J. 2007. RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. J Biol Chem 282, 14056-14064.
    • (2007) J Biol Chem , vol.282 , pp. 14056-14064
    • Roux, P.P.1    Shahbazian, D.2    Vu, H.3    Holz, M.K.4    Cohen, M.S.5    Taunton, J.6    Sonenberg, N.7    Blenis, J.8
  • 24
    • 0037227759 scopus 로고    scopus 로고
    • Acute response of net muscle protein balance reflects 24-h balance after exercise and amino acid ingestion
    • Tipton, K.D., Borsheim, E., Wolf, S.E., Sanford, A.P. & Wolfe, R.R. 2003. Acute response of net muscle protein balance reflects 24-h balance after exercise and amino acid ingestion. Am J Physiol Endocrinol Metab 284, E76-E89.
    • (2003) Am J Physiol Endocrinol Metab , vol.284
    • Tipton, K.D.1    Borsheim, E.2    Wolf, S.E.3    Sanford, A.P.4    Wolfe, R.R.5
  • 25
    • 33749431713 scopus 로고    scopus 로고
    • The mTOR pathway in the control of protein synthesis
    • Wang, X. & Proud, C.G. 2006. The mTOR pathway in the control of protein synthesis. Physiology (Bethesda) 21, 362-369.
    • (2006) Physiology (Bethesda) , vol.21 , pp. 362-369
    • Wang, X.1    Proud, C.G.2
  • 26
    • 0035881470 scopus 로고    scopus 로고
    • Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase
    • Wang, X., Li, W., Williams, M., Terada, N., Alessi, D.R. & Proud, C.G. 2001. Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase. EMBO J 20, 4370-4379.
    • (2001) EMBO J , vol.20 , pp. 4370-4379
    • Wang, X.1    Li, W.2    Williams, M.3    Terada, N.4    Alessi, D.R.5    Proud, C.G.6
  • 27
    • 0032981328 scopus 로고    scopus 로고
    • Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo
    • Waskiewicz, A.J., Johnson, J.C., Penn, B., Mahalingam, M., Kimball, S.R. & Cooper, J.A. 1999. Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo. Mol Cell Biol 19, 1871-1880.
    • (1999) Mol Cell Biol , vol.19 , pp. 1871-1880
    • Waskiewicz, A.J.1    Johnson, J.C.2    Penn, B.3    Mahalingam, M.4    Kimball, S.R.5    Cooper, J.A.6
  • 28
    • 34147094595 scopus 로고    scopus 로고
    • Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverage
    • Wilkinson, S.B., Tarnopolsky, M.A., Macdonald, M.J., MacDonald, J.R., Armstrong, D. & Phillips, S.M. 2007. Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverage. Am J Clin Nutr 85, 1031-1040.
    • (2007) Am J Clin Nutr , vol.85 , pp. 1031-1040
    • Wilkinson, S.B.1    Tarnopolsky, M.A.2    Macdonald, M.J.3    MacDonald, J.R.4    Armstrong, D.5    Phillips, S.M.6
  • 29
    • 48549107440 scopus 로고    scopus 로고
    • Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle
    • Wilkinson, S.B., Phillips, S.M., Atherton, P.J., Patel, R., Yarasheski, K.E., Tarnopolsky, M.A. & Rennie, M.J. 2008. Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle. J Physiol 586, 3701-3717.
    • (2008) J Physiol , vol.586 , pp. 3701-3717
    • Wilkinson, S.B.1    Phillips, S.M.2    Atherton, P.J.3    Patel, R.4    Yarasheski, K.E.5    Tarnopolsky, M.A.6    Rennie, M.J.7
  • 30
    • 0037444470 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase (MAPK) pathway activation: effects of age and acute exercise on human skeletal muscle
    • Williamson, D., Gallagher, P., Harber, M., Hollon, C. & Trappe, S. 2003. Mitogen-activated protein kinase (MAPK) pathway activation: effects of age and acute exercise on human skeletal muscle. J Physiol 547, 977-987.
    • (2003) J Physiol , vol.547 , pp. 977-987
    • Williamson, D.1    Gallagher, P.2    Harber, M.3    Hollon, C.4    Trappe, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.