Real-time electrical impedance-based measurement to distinguish oral cancer cells and non-cancer oral epithelial cells

Analytical and Bioanalytical Chemistry

Volumn 399, Issue 5, 2011, Pages 1823-1833

  Yang, Liju ^a   Arias, L Renea ^a   Lane, Tonya S ^a   Yancey, Martez D ^a   Mamouni, Jaouad ^a  

^a NORTH CAROLINA CENTRAL UNIVERSITY   (United States)

Author keywords

Cellular activity; Electrodes; Impedance measurement; Non cancer oral epithelial cells; Oral cancer cells; Real time

Indexed keywords

CELLULAR ACTIVITIES; EPITHELIAL CELLS; IMPEDANCE MEASUREMENT; ORAL CANCER; REAL-TIME;

ADHESION; CELL ADHESION; CELL CULTURE; ELECTRIC IMPEDANCE; ELECTRIC IMPEDANCE MEASUREMENT; MICROELECTRODES; MICROSCOPIC EXAMINATION; MONOLAYERS;

CELLS;

ARTICLE; CELL ADHESION; CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; CONFOCAL MICROSCOPY; CYTOLOGY; EPITHELIUM CELL; HUMAN; IMPEDANCE; KINETICS; MICROELECTRODE; MOUTH TUMOR; PATHOLOGY; TIME;

CELL ADHESION; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; ELECTRIC IMPEDANCE; EPITHELIAL CELLS; HUMANS; KINETICS; MICROELECTRODES; MICROSCOPY, CONFOCAL; MOUTH NEOPLASMS; TIME FACTORS;

EID: 79251602595     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-010-4584-9     Document Type: Article

References (53)

1. Beenken SW, Urist MM (2003) In: Way LW, Doherty GM (eds.) Current surgical diagnosis and treatment, 11th ed. Lange Medical Books/McGraw-Hill, New York, pp 282-297
2. DM Walker G Boey LA McDonald 2003 The pathology of oral cancer Pathology 35 376 383 10.1080/00310290310001602558 (Pubitemid 37310977)
3. BW Neville TA Day 2002 Oral cancer and precancerous lesions CA Cancer J Clin 2 195 215 10.3322/canjclin.52.4.195
4. CDC (Centers for disease Control and Prevention). Preventing and controlling oral and pharyngeal cancer. Recommendations from a national strategic planning conference. MMWR 1998, 47(RR-14), 1-12
5. USDHHS (U.S. Department of Health and Human Services. Oral health in America: a report of the surgeon general-executive summary. Rockville (MD): US Department of Health and Human Service, National Institute of Dental and Craniofacial Research, National Institutes of Health; 2000, 1-13
6. MA Weinberg DJ Estefanm 2002 Assessing oral malignancies Am Fam Phys 65 1379 1384
7. K Pantel RJ Cote φ Fodstat 1999 Detection and clinical importance of micrometastatic disease J Natl Cancer Inst 91 3 1113 1124 1:STN:280: DyaK1Mzit1Sisw%3D%3D 10.1093/jnci/91.13.1113
8. C Dawes 2003 Estimate, from salivary analyses, of the turnover time of the oral mucosal epithelium in humans and the number of bacteria in an edentulous mouth Arch Oral Biol 48 329 336 1:STN:280:DC%2BD3s7pt1Slug%3D%3D 10.1016/S0003-9969(03)00014-1 (Pubitemid 36684429)
9. MG Mauk BL Ziober Z Chen J Thompson H Bau 2007 Lab-on-a-chip technologies for oral-based cancer screening and diagnostics Ann NY Acad Sci 1098 467 475 1:CAS:528:DC%2BD2sXltVKkt78%3D 10.1196/annals.1384.025 (Pubitemid 47092546)
10. G Boeck 2001 Current status of flow cytometry in cell and molecular biology Int Rev Cytol 204 239 298 1:CAS:528:DC%2BD3MXisFymsrY%3D 10.1016/S0074-7696(01)04006-2 (Pubitemid 32185173)
11. Basiji DA, Ortyn WE, Liang L, Venkatachalam V, Morrissey P (2007) Cellular image analysis and imaging by flow cytometry. Clin Lab Med 27(3): 653-viii
12. HP Schwan 1957 Electrical properties of tissue and cell suspensions Adv Biol Med Phys 5 147 209 1:CAS:528:DyaG1cXjtVCnug%3D%3D
13. S Takashima K Asami Y Takahashi 1988 Frequency domain studies of impedance characteristics of biological cells using micropipet technique Biophys J 54 995 1000 1:STN:280:DyaL1M7ms1Oruw%3D%3D 10.1016/S0006-3495(88)83037-6
14. HE Asami KS Zhao 1994 Dielectric measurement of a single sub-millimeter size microcapsule Colloids Polym Sci 272 64 71 1:CAS:528:DyaK2cXitF2ksL0%3D 10.1007/BF00653311
15. HE Ayliffe AB Frazier RD Rabbitt 1999 Electric impedance spectroscopy using microchannels with integrated metal electrodes J Microelectromechan Syst 8 50 57 10.1109/84.749402
16. Gawad S, Metz S, Schild L, Renaud P (2001) Impedance spectroscopy cell analysis in microchannels. Proceedings of the International Conference on Micro Total Analysis Systems, Monterey, CA, USA, pp 253-255
17. Gawad S, Wuthrich M, Schild L, Dubochet O, Renaud P, Obermeier E (2001b) On-chip impedance spectroscopy of flow-cytometry using a differential electrode sensor. In: Proceedings of the International Conference on Solid Sensors and Actuators. Transducers 01, Munich, Germany, pp1190-1193
18. Huang Y, Chen N, Borninski J, Rubinsky B (2003) A novel microfluidic cell-chip for single cell analysis and manipulation. Proceedings of the International Conference on Microelectromechical System, Kyoto, Japan, pp 403-406
19. Mohanty SK, Ravula SK, Engisch KL, Frazier AB (2003) A micro system using dielectrophoresis and electrical impedance spectroscopy for cell manipulation and analysis. In: Proceedings of the International Conference on Solid State Sensors and Actuators, Transducers 03, Boston, USA, pp. 1055-1058
20. I Giaever CR Keese 1984 Monitoring fibroblast behavior in tissue culture with an applied electric field Proc Natl Acad Sci USA 81 3761 3764 1:STN:280:DyaL2c3it1SgtA%3D%3D 10.1073/pnas.81.12.3761
21. I Giaever CR Keese 1991 Micromotion of mammalian cells measured electrically Proc Natl Acad Sci USA 88 7896 900 1:STN:280:DyaK3Mzlt1Squg%3D%3D 10.1073/pnas.88.17.7896
22. Giaever I, Keese CR (1992) Toxic? Cells can tell. Chemtech 116-125
23. I Giaever CR Keese 1993 A morphological biosensor for mammalian cells Nature 366 591 592 1:STN:280:DyaK2c%2FnslWrtQ%3D%3D 10.1038/366591a0 (Pubitemid 24036004)
24. J Wegener CR Keese I Giaever 2000 Electric cell-substrate impedance sensing (ECIS) as a noninvasive means to monitor the kinetics of cell spreading to artificial surfaces Exp Cell Res 259 158 166 1:CAS:528:DC%2BD3cXls1ansbw%3D 10.1006/excr.2000.4919
25. R Ehret W Baumann M Brischwein A Schwinde K Stegbauer B Wolf 1997 Monitoring of cellular behavior by impedance measurements on interdigitated electrode structures Biosens Bioelectron 12 29 41 1:CAS:528:DyaK28XnsFahu7o%3D 10.1016/0956-5663(96)89087-7 (Pubitemid 26398077)
26. R Ehret W Baumann M Brischwein A Schwinde B Wolf 1998 On-line control of cellular adhesion with impedance measurements using interdigitated electrode structures Med Biol Eng Comput 36 365 70 1:STN:280:DyaK1cvhvFOitA%3D%3D 10.1007/BF02522485 (Pubitemid 28258617)
27. K Solly X Wang X Xu B Strulovici W Zheng 2004 Application of real-time cell electronic sensing (RT-CES) technology to cell-based assays Assay Drug Dev Technol 2 363 372 1:CAS:528:DC%2BD2cXntlGktr4%3D 10.1089/adt.2004.2.363 (Pubitemid 39276278)
28. P Linderholm J Vannod Y Barrandon P Renaud 2007 Bipolar resistivity profiling of 3D tissue culture Biosens Bioelectron 22 789 796 1:CAS:528:DC%2BD28Xhtlalsb%2FE 10.1016/j.bios.2006.02.016 (Pubitemid 44894856)
29. R McGuinness 2007 Impedance-based cellular assay technologies: recent advances, future promise Cur Opin Pharmacol 7 535 540 1:CAS:528: DC%2BD2sXhtF2htbvI 10.1016/j.coph.2007.08.004 (Pubitemid 47560223)
30. BD Klo R Kurz HG Jahnke M Fischer S Rothermel U Anderegg JC Simon AA Robitzki 2008 Microcavity array (MCA)-based biosensor chip for functional drug screening of 3D tissue models Biosens Bioelectron 23 1473 1480 10.1016/j.bios.2008.01.003
31. Y Chen J Zhang Y Wang L Zhang R Julien K Tang N Balasubramanian 2008 Real-time monitoring approach: assessment of effects of antibodies on the adhesion of NCI-H460 cancer cells to the extracellular matrix Biosens Bioelectron 23 1390 1396 10.1016/j.bios.2007.12.006
32. Q Liu J Yu L Xiao JCO Tang Y Zhang P Wang M Yang 2009 Impedance studies of bio-behavior and chemosensitivity of cancer cells by micro-electrode arrays Biosens Bioelectron 24 1305 1310 1:CAS:528:DC%2BD1MXksVeqsA%3D%3D 10.1016/j.bios.2008.07.044
33. G Park CK Choi AE English TE Sparer 2009 Electrical impedance measurements predict cellular transformation Cell Biol Int 33 429 433 1:CAS:528:DC%2BD1MXivVWls7o%3D 10.1016/j.cellbi.2009.01.013
34. LR Arias AC Perry L Yang 2010 Real-time electrical impedance detection of cellular activities of oral cancer cells Biosens Bioelectron 25 2225 2231 1:CAS:528:DC%2BC3cXlvVegsr8%3D 10.1016/j.bios.2010.02.029
35. Silverman S Jr (1991) Oral cancer, 3rd edn. The American Cancer Society, Inc., Atlanta
36. LM Broche N Bhadal MP Lewis S Porter MP Hughes FH Labeed 2007 Early detection of oral cancer-is dielectrophoresis the answer? Oral Oncol 43 2 199 203 1:CAS:528:DC%2BD2sXhtleit7w%3D 10.1016/j.oraloncology.2006.02.012 (Pubitemid 46176709)
37. K-H Han A Han AB Frazier 2006 Microsystem for isolation and electrophysological analysis of breast cancer cells from blood Biosens Bioelectrons 21 1907 1914 1:CAS:528:DC%2BD28XivVOisr4%3D 10.1016/j.bios.2006.01. 024
38. GS Orlando NA Tobbey P Wang S Abdulnour-Nakhoul RC Orlando 2002 Regulatory volume decrease in human esophageal epithelial cells Am J Physiol Gastrointest Liver Physiol 283 G932 G937 1:CAS:528:DC%2BD38XotV2qsLo%3D
39. GD Stoner ME Kaighn RR Reddel JH Resau D Bowman Z Naito N Matsukura M You AJ Galati CC Harris 1991 Establishment and characterization of SV40T-antigen immortalized human esophageal epithelial cells Cancer Res 51 365 371 1:STN:280:DyaK3M7gsFKlsw%3D%3D
40. N Boudreau MJ Bissell 1998 Extracellular matrix signaling: integration of form and function in normal and malignant cells Curr Opin Cell Biol 10 640 646 1:CAS:528:DyaK1cXntVSgu7o%3D 10.1016/S0955-0674(98)80040-9 (Pubitemid 28477023)
41. MA Schwartz MH Ginsberg 2002 Networks and crosstalk: integrin signalling spreads Nat Cell Biol 4 E65 68 1:CAS:528:DC%2BD38XivV2jtr4%3D 10.1038/ncb0402-e65 (Pubitemid 34308840)
42. CS Chen JL Alonso E Ostuni GM Whitesides DE Ingber 2003 Cell shape provides global control of focal adhesion assembly Biochem Biophys Res Commun 307 355 361 1:CAS:528:DC%2BD3sXlt1arur8%3D 10.1016/S0006-291X(03)01165-3 (Pubitemid 36818878)
43. RM Ezzell WH Goldmann N Wang N Parasharama DE Ingber 1997 Vinculin promotes cell spreading by mechanically coupling integrins to the cytoskeleton Exp Cell Res 231 14 26 1:CAS:528:DyaK2sXhsVKmsLk%3D 10.1006/excr.1996.3451 (Pubitemid 27187510)
44. JD Owen PJ Ruest DW Fry SK Hanks 1999 Induced focal adhesion kinase (FAK) Expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of pyk2 Mol Cell Biol 19 4806 4818 1:CAS:528:DyaK1MXktVCgsbg%3D
45. NQ Balaban UA Schwarz D Riveline P Goichberg G Tzur I Sabanay D Mahalu S Safran A Bershadsky L Addadi B Geiger 2001 Calculation of forces at focal adhesions from elastic substrate data: the effect of localized force and the need for regularization Nat Cell Biol 3 466 472 1:CAS:528:DC%2BD3MXjsFCksr0%3D 10.1038/35074532 (Pubitemid 32422082)
46. D Riveline E Zamir NQ Balaban US Schwarz T Ishizaki S Narumiya Z Kam B Geiger AD Bershadsky 2001 Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism J Cell Biol 153 1175 1186 1:CAS:528: DC%2BD3MXktlOmsLc%3D 10.1083/jcb.153.6.1175 (Pubitemid 34289257)
47. N Wang E Ostuni GM Whitesides J DE Ingber 2002 Micropatterning tractional forces in living cells Cell Motil Cytoskel 2 97 106 10.1002/cm.10037 (Pubitemid 34568960)
48. JL Tan J Tien DM Pirone DS Gray K Bhadriraju CS Chen 2003 Cells lying on a bed of microneedles: an approach to isolate mechanical force Proc Acad Sci USA 100 1484 1489 1:CAS:528:DC%2BD3sXhsFGksbk%3D 10.1073/pnas.0235407100 (Pubitemid 36254472)
49. F Asphahani M Thein O Veiseh D Edmondson R Kosai M Veiseh J Xu M Zhang 2008 Influence of cell adhesion and spreading on impedance characteristics of cell-based sensors Biosens Bioelectron 23 1307 1313 1:CAS:528: DC%2BD1cXislWjurs%3D 10.1016/j.bios.2007.11.021
50. J Massano FS Regateiro G Januario A Ferreira 2006 Oral squamous cell carcinoma: review of prognostic and predictive factors Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102 67 76 10.1016/j.tripleo.2005.07.038 (Pubitemid 44016111)
51. E Mendez C Cheng DG Farwell S Ricks SN Agoff ND Futran EA Weymuller Jr NC Maronian LP Zhao C Chen 2002 Transcriptional expression profiles of oral squamous cell carcinomas Cancer 95 1482 1494 1:CAS:528:DC%2BD38XnvV2qtbk%3D 10.1002/cncr.10875
52. M Thein F Asphahani A Chang R Buckmaster M Zhang J Xu 2010 Response characteristics of single-cell impedance sensors employed with surface-modified microelectrodes Biosens Bioelectron 25 1963 1969 1:CAS:528:DC%2BC3cXjtVCqur8%3D 10.1016/j.bios.2010.01.023
53. DS Gray JL Tan J Voldman CS Chen 2004 Dielectrophoretic registration of living cells to a microelectrode array Biosens Bioelectron 19 1765 1774 1:CAS:528:DC%2BD2cXktV2lur4%3D 10.1016/j.bios.2004.03.016 (Pubitemid 38622249)