Serum CCL2 and serum TNF-α - Two new biomarkers predict bone invasion, post-treatment distant metastasis and poor overall survival in nasopharyngeal carcinoma

European Journal of Cancer

Volumn 47, Issue 3, 2011, Pages 339-346

  Lu, Xing ^a   Qian, Chao Nan ^a   Mu, Yong Gao ^a   Li, Ning Wei ^a   Li, Su ^a   Zhang, Hai Bo ^a   Li, Si Wei ^a   Wang, Fei Li ^a   Guo, Xiang ^a   Xiang, Yan Qun ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

Author keywords

Bone; CCL2; Nasopharyngeal carcinoma; Prognosis; Serum; TNF

Indexed keywords

BIOLOGICAL MARKER; CISPLATIN; FLUOROURACIL; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BONE METASTASIS; CANCER CHEMOTHERAPY; CANCER INVASION; CANCER STAGING; DISTANT METASTASIS; DRUG MEGADOSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE CYCLE TREATMENT; NASOPHARYNX CARCINOMA; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; SKULL BASE;

ADULT; ANTINEOPLASTIC AGENTS; BONE NEOPLASMS; CHEMOKINE CCL2; DISEASE-FREE SURVIVAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 79251600223     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2010.09.025     Document Type: Article

References (26)

1. W. Hu, W. Ding, and H. Yang Weekly paclitaxel with concurrent radiotherapy followed by adjuvant chemotherapy in locally advanced nasopharyngeal carcinoma Radiother Oncol 93 2009 488 491
2. S. Paget The distribution of secondary growths in cancer of the breast Cancer Metastasis Rev 8 1989 98 101
3. J. Peng, T. Ding, L.M. Zheng, and J.Y. Shao Influence of tumour-associated macrophages on progression and prognosis of nasopharyngeal carcinoma Ai Zheng 25 2006 1340 1345
4. F. Bolat, F. Kayaselcuk, and T.Z. Nursal Microvessel density, VEGF expression, and tumour-associated macrophages in breast tumours: correlations with prognostic parameters J Exp Clin Cancer Res 25 2006 365 372
5. I.F. Lissbrant, P. Stattin, and P. Wikstrom Tumour associated macrophages in human prostate cancer: relation to clinicopathological variables and survival Int J Oncol 17 2000 445 451
6. K. Matsushima, C.G. Larsen, G.C. DuBois, and J.J. Oppenheim Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line J Exp Med 169 1999 1485 1490
7. M. Ohta, Y. Kitadai, and S. Tanaka Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumour vascularity in human esophageal squamous cell carcinomas Int J Cancer 102 2002 220 224
8. Y. Lu, Z. Cai, and G. Xiao CCR2 expression correlates with prostate cancer progression J Cell Biochem 101 2007 676 685
9. R.D. Loberg, C. Ying, and M. Craig CCL2 as an important mediator of prostate cancer growth in vivo through the regulation of macrophage infiltration Neoplasia 9 2007 556 562
10. T. Ueno, M. Toi, and H. Saji Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer Clin Cancer Res 6 2000 3282 3289
11. J. Nakashima, M. Tachibana, and M. Ueno Association between tumour necrosis factor in serum and cachexia in patients with prostate cancer Clin Cancer Res 4 1998 1743 1748
12. H.A. Sati, M. Greaves, J.F. Apperley, R.G.G. Russell, and P.I. Croucher Expression of interleukin-1b and tumour necrosis factor-a in plasma cells from patients with multiple myeloma Brit J Haematol 104 1999 350 357
13. S.H. Hsiao, M.S. Lee, and H.Y. Lin Clinical significance of measuring levels of tumour necrosis factor-alpha and soluble interleukin-2 receptor in nasopharyngeal carcinoma Acta Otolaryngol 23 2009 1 5
14. R.D. Loberg, L.L. Day, and J. Harwood CCL2 is a potent regulator of prostate cancer cell migration and proliferation Neoplasia 8 2006 578 586
15. J.W. Pollard Tumour-educated macrophages promote tumour progression and metastasis Nat Rev Cancer 4 2004 71 78
16. Y. Lu, Z. Cai, and D.L. Galson Monocyte chemotactic protain-1 (MCP-1) acts as a paracrine and autocrine factor for prostate cancer growth and invasion The prostate 66 2006 1311 1318
17. K.F. Tang, S.Y. Tan, and S.H. Chan A distinct expression of CC chemokines by macrophages in nasopharyngeal carcinoma: implication for the intense tumour infiltration by T lymphocytes and macrophages Human Pathol 32 2001 42 49
18. R.P. Negus, G.W. Stamp, and M.G. Relf The detection and localization of monocyte chemoattractant protein-1 (MCP-1) in human ovarian cancer J Clin Invest 95 1995 2391 2396
19. M. Ohta, Y. Kitadai, and S. Tanaka Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumour vascularity in human esophageal squamous cell carcinomas Int J Cancer 102 2002 220 224
20. T. Valkovic, K. Lucin, M. Krstulja, R. Dobi-Babic, and N. Jonjic Expression of monocyte chemotactic protein-1 in human invasive ductal breast cancer Pathol Res Pract 194 1998 335 340
21. B.Z. Qian, and J.W. Pollard Macrophage diversity enhances tumour progression and metastasis Cell 141 2010 39 51
22. A. Sica, T. Schioppa, A. Mantovani, and P. Allavena Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy Eur J Cancer 42 2006 717 727
23. Y. Lu, Z. Cai, and G. Xiao Monocyte chemotactic protein-1 mediates prostate cancer-induced bone resorption Cancer Res 67 2007 3646 3653
24. K. Vanderkerken, I. Vande Broek, and D.L. Eizirik Monocyte chemoattractant protein-1 (MCP-1), secreted by bone marrow endothelial cells, induces chemoattraction of 5T multiple myeloma cells Clin Exp Metastasis 19 2002 87 90
25. M.J. Craig, and R.D. Loberg CCL2 (monocyte chemoattractant protein-1) in cancer bone metastasis Cancer Metastasis Rev 25 2006 611 619
26. D.W. Miles, L.C. Happerfield, and M.S. Naylor Expression of tumour necrosis factor (TNFa) and its receptors in benign and malignant breast tissue Int J Cancer 56 1994 777 782