The effect of a single bolus of exogenous surfactant on lung compliance persists until two weeks after treatment in a model of acid aspiration pneumonitis

Pulmonary Pharmacology and Therapeutics

Volumn 24, Issue 1, 2011, Pages 141-146

  Scanziani, Margherita ^a,b   Amigoni, Maria ^a,b   Bellani, Giacomo ^a,b   Zambelli, Vanessa ^a,c   Masson, Serge ^c   Radaelli, Enrico ^d   Pesenti, Antonio ^a,b   Latini, Roberto ^c  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b SAN GERARDO HOSPITAL   (Italy)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

Acid aspiration syndrome; Acute lung injury; Mice; Pulmonary surfactant

Indexed keywords

HYDROCHLORIC ACID; PHOSPHOLIPID; PORACTANT; SODIUM CHLORIDE;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL CARBON DIOXIDE TENSION; ARTERIAL GAS; ARTERIAL OXYGEN TENSION; ARTICLE; ASPIRATION PNEUMONIA; BREATHING RATE; CELL FRACTIONATION; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HISTOPATHOLOGY; INFLAMMATORY INFILTRATE; LUNG COMPLIANCE; LUNG FUNCTION; LUNG LAVAGE; MACROPHAGE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NEUTROPHIL; NONHUMAN; OXYGENATION; POLYMORPHONUCLEAR CELL; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; SINGLE DRUG DOSE; TIDAL VOLUME; TREATMENT RESPONSE;

ACUTE LUNG INJURY; ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; LEUKOCYTE COUNT; LUNG; LUNG COMPLIANCE; MICE; PNEUMONIA, ASPIRATION; PULMONARY SURFACTANTS;

EID: 79251595591     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2010.07.004     Document Type: Article

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