Comparison of rSP-C surfactant with natural and synthetic surfactants after late treatment in a rat model of the acute respiratory distress syndrome

British Journal of Pharmacology

Volumn 124, Issue 6, 1998, Pages 1083-1090

  Häfner, Dietrich ^a,c   Germann, Paul Georg ^b   Hauschke, Dieter ^c  

^a Dept of Respiratory Pharmacology ^*  (Germany)

^b Dept of Respiratory Pharmacology   (Germany)

^c ALTANA PHARMA AG   (Germany)

Author keywords

ARDS model; Bovine derived surfactant; Dose response comparisons; Gas exchange; rSP C; Synthetic surfactant

Indexed keywords

LUNG SURFACTANT; LUNG SURFACTANT EXTRACT; PHOSPHOLIPID; PL SURFACTANT; PROTEIN; SURFACTANT; UNCLASSIFIED DRUG;

ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL OXYGEN TENSION; ARTICLE; ARTIFICIAL VENTILATION; BREATHING RATE; CONTROLLED STUDY; DOSE RESPONSE; GAS EXCHANGE; INTRATRACHEAL DRUG ADMINISTRATION; LUNG LAVAGE; MALE; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RAT; RESPIRATORY DISTRESS;

ACUTE DISEASE; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; PROTEOLIPIDS; PULMONARY SURFACTANTS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; RESPIRATORY DISTRESS SYNDROME, ADULT;

EID: 0031857891     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701931     Document Type: Article

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