Using Drosophila Larval Imaginal Discs to Study Low-Dose Radiation-Induced Cell Cycle Arrest

Methods in Molecular Biology

Volumn 782, Issue , 2011, Pages 93-103

  Yan, Shian Jang ^a   Li, Willis X ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

cell cycle arrest; checkpoint; Drosophila; imaginal discs; larvae; mitosis; radiation

Indexed keywords

ANIMAL; ARTICLE; CELL CYCLE CHECKPOINT; CYTOLOGY; DROSOPHILA; DRUG EFFECT; IMAGINAL DISC; LARVA; RADIATION EXPOSURE;

ANIMALS; CELL CYCLE CHECKPOINTS; DROSOPHILA; IMAGINAL DISCS; LARVA;

EID: 79251591672     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-61779-273-1_8     Document Type: Chapter

References (16)

1. Yan, S. J., Lim, S. J., Shi, S., Dutta, P., and Li, W. X. (2011) Unphosphorylated STAT and heterochromatin protect genome stability, FASEB J. 1, 232–241.
2. Morgan, T. H. (1910) Sex limited inheritance in Drosophila, Science 32, 120–122.
3. Bellen, H. J., Tong, C., and Tsuda, H. (2010) 100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future, Nat Rev Neurosci 11, 514–522.
4. Cohen, B. (1995) Nobel committee rewards pioneers of development studies in fruitflies, Nature 377, 465.
5. Raju, T. N. (1999) The Nobel chronicles. 1933: Thomas Hunt Morgan (1866–1945), Lancet 353, 157.
6. Elledge, S. J. (1996) Cell cycle checkpoints: preventing an identity crisis, Science 274, 1664–1672.
7. Song, Y. H. (2005) Drosophila melanogaster: a model for the study of DNA damage checkpoint response, Mol Cells 19, 167–179.
8. Weatherbee, S. D., and Carroll, S. B. (1999) Selector genes and limb identity in arthropods and vertebrates, Cell 97, 283–286.
9. Yan, S. J., Gu, Y., Li, W. X., and Fleming, R. J. (2004) Multiple signaling pathways and a selector protein sequentially regulate Drosophila wing development, Development 131, 285–298.
10. Garcia-Bellido, A., and Merriam, J. R. (1971) Parameters of the wing imaginal disc development of Drosophila melanogaster, Dev Biol 24, 61–87.
11. Brand, A. H., and Perrimon, N. (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes, Development 118, 401–415.
12. Dietzl, G., Chen, D., Schnorrer, F., Su, K. C., Barinova, Y., Fellner, M., Gasser, B., Kinsey, K., Oppel, S., Scheiblauer, S., Couto, A., Marra, V., Keleman, K., and Dickson, B. J. (2007) A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila, Nature 448, 151–156.
13. Loya, C. M., Lu, C. S., Van Vactor, D., and Fulga, T. A. (2009) Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms, Nat Methods 6, 897–903.
14. Pospisilik, J. A., Schramek, D., Schnidar, H., Cronin, S. J., Nehme, N. T., Zhang, X., Knauf, C., Cani, P. D., Aumayr, K., Todoric, J., Bayer, M., Haschemi, A., Puvi-indran, V., Tar, K., Orthofer, M., Neely, G. G., Dietzl, G., Manoukian, A., Funovics, M., Prager, G., Wagner, O., Ferrandon, D., Aberger, F., Hui, C. C., Esterbauer, H., and Penninger, J. M. (2010) Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate, Cell 140, 148–160.
15. Neely, G. G., Kuba, K., Cammarato, A., Isobe, K., Amann, S., Zhang, L., Murata, M., Elmen, L., Gupta, V., Arora, S., Sarangi, R., Dan, D., Fujisawa, S., Usami, T., Xia, C. P., Keene, A. C., Alayari, N. N., Yamakawa, H., Elling, U., Berger, C., Novatchkova, M., Koglgruber, R., Fukuda, K., Nishina, H., Isobe, M., Pospisilik, J. A., Imai, Y., Pfeufer, A., Hicks, A. A., Pramstaller, P. P., Subramaniam, S., Kimura, A., Ocorr, K., Bodmer, R., and Penninger, J. M. (2010) A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function, Cell 141, 142–153.
16. Bodenstein, D. (1994) The postembryonic development of Drosophila. In Biology of Drosophila (ed. M. Demerec), Facsimile edn., pp. 275–367, Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.