-
1
-
-
0016748441
-
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides
-
Hamberg M, Svensson J, Samuelsson B. Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. Proc Natl Acad Sci USA 1975; 72: 2994-8.
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 2994-2998
-
-
Hamberg, M.1
Svensson, J.2
Samuelsson, B.3
-
2
-
-
0017309767
-
Identification of an enzyme in platelet microsomes which generates Thromboxane A2 from prostaglandin endoperoxides
-
Needleman P, Moncada S, Bunting S, Vane JR, Hamberg M, Samuelsson B. Identification of an enzyme in platelet microsomes which generates Thromboxane A2 from prostaglandin endoperoxides. Nature 1976; 261: 558-60.
-
(1976)
Nature
, vol.261
, pp. 558-560
-
-
Needleman, P.1
Moncada, S.2
Bunting, S.3
Vane, J.R.4
Hamberg, M.5
Samuelsson, B.6
-
3
-
-
0017094798
-
An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
-
Moncada S, Gryglewski R, Bunting S, Vane JR. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature 1976; 263: 663-5.
-
(1976)
Nature
, vol.263
, pp. 663-665
-
-
Moncada, S.1
Gryglewski, R.2
Bunting, S.3
Vane, J.R.4
-
4
-
-
0017338997
-
Human arterial and venous tissues generate prostacyclin (prostaglandin x), a potential inhibitor of platelet aggregation
-
Moncada S, Gryglewski R, Bunting S, Vane JR. Human arterial and venous tissues generate prostacyclin (prostaglandin x), a potential inhibitor of platelet aggregation. Lancet 1977; 1: 18-20.
-
(1977)
Lancet
, vol.1
, pp. 18-20
-
-
Moncada, S.1
Gryglewski, R.2
Bunting, S.3
Vane, J.R.4
-
5
-
-
0018745134
-
Characterization of prostacyclin synthesis in cultured human arterial smooth muscle cells, venous endothelial cells and skin fibroblasts
-
Baenziger NL, Becherer PR, Majerus PW. Characterization of prostacyclin synthesis in cultured human arterial smooth muscle cells, venous endothelial cells and skin fibroblasts. Cell 1979; 16: 967-74.
-
(1979)
Cell
, vol.16
, pp. 967-974
-
-
Baenziger, N.L.1
Becherer, P.R.2
Majerus, P.W.3
-
6
-
-
22444441665
-
Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis
-
Hippisley-Cox J, Coupland C. Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis. Br Med J 2005; 330: 1366-73.
-
(2005)
Br Med J
, vol.330
, pp. 1366-1373
-
-
Hippisley-Cox, J.1
Coupland, C.2
-
7
-
-
58549116775
-
Risk of myocardial infarction and death associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) among healthy individuals: a nationwide cohort study
-
Fosbøl EL, Gislason GH, Jacobsen S, Folke F, Hansen ML, Schramm TK, Sørensen R, Rasmussen JN, Andersen SS, Abildstrom SZ, Traerup J, Poulsen HE, Rasmussen S, Køber L, Torp-Pedersen C. Risk of myocardial infarction and death associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) among healthy individuals: a nationwide cohort study. Clin Pharmacol Ther 2009; 85: 190-7.
-
(2009)
Clin Pharmacol Ther
, vol.85
, pp. 190-197
-
-
Fosbøl, E.L.1
Gislason, G.H.2
Jacobsen, S.3
Folke, F.4
Hansen, M.L.5
Schramm, T.K.6
Sørensen, R.7
Rasmussen, J.N.8
Andersen, S.S.9
Abildstrom, S.Z.10
Traerup, J.11
Poulsen, H.E.12
Rasmussen, S.13
Køber, L.14
Torp-Pedersen, C.15
-
8
-
-
0035934070
-
Risk of cardiovascular events associated with selective COX-2 inhibitors
-
Mukherjee D, Nissen SE, Topol EJ. Risk of cardiovascular events associated with selective COX-2 inhibitors. JAMA 2001; 286: 954-9.
-
(2001)
JAMA
, vol.286
, pp. 954-959
-
-
Mukherjee, D.1
Nissen, S.E.2
Topol, E.J.3
-
9
-
-
42449093389
-
Cardiovascular risk of celecoxib in randomized placebo-controlled trials: the cross trial safety analysis
-
Solomon SD, Wittes J, Finn PV, Fowler R, Viner J, Bertagnolli MM, Arber N, Levin B, Meinert CL, Martin B, Pater JL, Goss PE, Lance P, Obara S, Chew EY, Kim J, Arndt G, Hawk E. Cardiovascular risk of celecoxib in randomized placebo-controlled trials: the cross trial safety analysis. Circulation 2008; 117: 2104-13.
-
(2008)
Circulation
, vol.117
, pp. 2104-2113
-
-
Solomon, S.D.1
Wittes, J.2
Finn, P.V.3
Fowler, R.4
Viner, J.5
Bertagnolli, M.M.6
Arber, N.7
Levin, B.8
Meinert, C.L.9
Martin, B.10
Pater, J.L.11
Goss, P.E.12
Lance, P.13
Obara, S.14
Chew, E.Y.15
Kim, J.16
Arndt, G.17
Hawk, E.18
-
10
-
-
33749339372
-
Cardiovascular risk and inhibition of cyclooxygenase
-
McGettigan P, Henry D. Cardiovascular risk and inhibition of cyclooxygenase. JAMA 2006; 296: 1633-44.
-
(2006)
JAMA
, vol.296
, pp. 1633-1644
-
-
McGettigan, P.1
Henry, D.2
-
11
-
-
31044441042
-
Biologic basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities
-
Grosser T, Fries S, FitzGerald GA. Biologic basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities. J Clin Invest 2006; 116: 4-16.
-
(2006)
J Clin Invest
, vol.116
, pp. 4-16
-
-
Grosser, T.1
Fries, S.2
FitzGerald, G.A.3
-
12
-
-
0033377768
-
COX-2 is not involved in Thromboxane biosynthesis by activated human platelets
-
Patrignani P, Sciulli MG, Manarini S, Santini G, Cerletti C, Evangelista V. COX-2 is not involved in Thromboxane biosynthesis by activated human platelets. J Physiol Pharmacol 1999; 50: 661-7.
-
(1999)
J Physiol Pharmacol
, vol.50
, pp. 661-667
-
-
Patrignani, P.1
Sciulli, M.G.2
Manarini, S.3
Santini, G.4
Cerletti, C.5
Evangelista, V.6
-
13
-
-
0034702914
-
Cyclooxygenase-1 and -2- dependent prostacyclin formation in patients with atherosclerosis
-
Belton O, Byrne D, Kearney D, Leahy A, Fitzgerald DJ. Cyclooxygenase-1 and -2- dependent prostacyclin formation in patients with atherosclerosis. Circulation 2000; 02: 840-5.
-
(2000)
Circulation
, vol.2
, pp. 840-845
-
-
Belton, O.1
Byrne, D.2
Kearney, D.3
Leahy, A.4
Fitzgerald, D.J.5
-
14
-
-
0034900837
-
Effects of COX-2 inhibitors on aortic prostacyclin production in cholesterol-fed rabbits
-
Wong E, Huang J, Tagari P, Riendeau D. Effects of COX-2 inhibitors on aortic prostacyclin production in cholesterol-fed rabbits. Atherosclerosis 2001; 157: 393-402.
-
(2001)
Atherosclerosis
, vol.157
, pp. 393-402
-
-
Wong, E.1
Huang, J.2
Tagari, P.3
Riendeau, D.4
-
15
-
-
0028814935
-
Differential measurement of constitutive (COX-1) and inducible (COX-2) cyclooxygenase expression in human umbilical vein endothelial cells using specific immunometic enzyme immunoassays
-
Créminon C, Habib A, Maclouf J, Pradelles P, Grassi J, Frobert Y. Differential measurement of constitutive (COX-1) and inducible (COX-2) cyclooxygenase expression in human umbilical vein endothelial cells using specific immunometic enzyme immunoassays. Biochim Biophys Acta 1995; 1254: 341-8.
-
(1995)
Biochim Biophys Acta
, vol.1254
, pp. 341-348
-
-
Créminon, C.1
Habib, A.2
Maclouf, J.3
Pradelles, P.4
Grassi, J.5
Frobert, Y.6
-
16
-
-
21844451360
-
COX-2-derived prostacyclin modulates vascular remodeling
-
Rudic RD, Brinster D, Cheng Y, Fries S, Song WL, Austin S, Coffman TM, FitzGerald GA. COX-2-derived prostacyclin modulates vascular remodeling. Circ Res 2005; 96: 1240-7.
-
(2005)
Circ Res
, vol.96
, pp. 1240-1247
-
-
Rudic, R.D.1
Brinster, D.2
Cheng, Y.3
Fries, S.4
Song, W.L.5
Austin, S.6
Coffman, T.M.7
FitzGerald, G.A.8
-
17
-
-
0029790770
-
Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress
-
Topper JN, Cai J, Falb D, Gimbrone MA Jr. Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci USA 1996; 93: 10417-22.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10417-10422
-
-
Topper, J.N.1
Cai, J.2
Falb, D.3
Gimbrone Jr, M.A.4
-
18
-
-
60649095647
-
Effects of a stable prostacyclin analogue beraprost sodium on VEGF and PAI-1 gene expression in vascular smooth muscle cells
-
Atsuta H, Uchiyama T, Kanai H, Iso T, Tanaka T, Suga T, Maeno T, Arai M, Nagai R, Kurabayashi M. Effects of a stable prostacyclin analogue beraprost sodium on VEGF and PAI-1 gene expression in vascular smooth muscle cells. Int J Cardiol 2009; 132: 411-8.
-
(2009)
Int J Cardiol
, vol.132
, pp. 411-418
-
-
Atsuta, H.1
Uchiyama, T.2
Kanai, H.3
Iso, T.4
Tanaka, T.5
Suga, T.6
Maeno, T.7
Arai, M.8
Nagai, R.9
Kurabayashi, M.10
-
20
-
-
0032879791
-
Short- and long-term treatments with iloprost in diabetic patients with peripheral vascular disease: effects on the cardiovascular risk factor plasminogen activator inhibitor type-1
-
Cozzolino D, Coppola L, Masi S, Salvatore T, Sasso F, Lucia D, Gentile S, Torella R. Short- and long-term treatments with iloprost in diabetic patients with peripheral vascular disease: effects on the cardiovascular risk factor plasminogen activator inhibitor type-1. Eur J Clin Pharmacol 1999; 55: 491-4979.
-
(1999)
Eur J Clin Pharmacol
, vol.55
, pp. 491-4979
-
-
Cozzolino, D.1
Coppola, L.2
Masi, S.3
Salvatore, T.4
Sasso, F.5
Lucia, D.6
Gentile, S.7
Torella, R.8
-
21
-
-
0034650976
-
Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice
-
Eitzman D, Westrick R, Nabel E, Ginsburg D. Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice. Blood 2000; 95: 577-80.
-
(2000)
Blood
, vol.95
, pp. 577-580
-
-
Eitzman, D.1
Westrick, R.2
Nabel, E.3
Ginsburg, D.4
-
22
-
-
0034660437
-
Plasminogen-activator inhibitor type 1 and coronary artery disease
-
Kohler HP, Grant PJ. Plasminogen-activator inhibitor type 1 and coronary artery disease. N Engl J Med 2000; 342: 1792-801.
-
(2000)
N Engl J Med
, vol.342
, pp. 1792-1801
-
-
Kohler, H.P.1
Grant, P.J.2
-
23
-
-
0023185776
-
Plasminogen activator inhibitor in plasma: risk factor for recurrent myocardial infarction
-
Hamsten A, de Faire U, Walldius G, Dahlén G, Szamosi A, Landou C, Blombäck M, Wiman B. Plasminogen activator inhibitor in plasma: risk factor for recurrent myocardial infarction. Lancet 1987; 2: 3.
-
(1987)
Lancet
, vol.2
, pp. 3
-
-
Hamsten, A.1
de Faire, U.2
Walldius, G.3
Dahlén, G.4
Szamosi, A.5
Landou, C.6
Blombäck, M.7
Wiman, B.8
-
24
-
-
0037162388
-
Age-dependent spontaneious coronary arterial thrombosis in transgenic mice that express a stable form of human plasminogen activator inhibitor-1
-
Eren M, Painter CA, Atkinson JB, Declerck PJ, Vaughan DE. Age-dependent spontaneious coronary arterial thrombosis in transgenic mice that express a stable form of human plasminogen activator inhibitor-1. Circulation 2002; 106: 491-6.
-
(2002)
Circulation
, vol.106
, pp. 491-496
-
-
Eren, M.1
Painter, C.A.2
Atkinson, J.B.3
Declerck, P.J.4
Vaughan, D.E.5
-
25
-
-
19244384861
-
Enhanced thrombosis in atherosclerosis-prone mice is associated with increased arterial expression of plasminogen activator inhibitor-1
-
Schafer K, Muller K, Hecke A, Mounier E, Goebel J, Loskutoff D, Konstantinides S. Enhanced thrombosis in atherosclerosis-prone mice is associated with increased arterial expression of plasminogen activator inhibitor-1. Arterioscler Thromb Vasc Biol 2008; 23: 2097-103.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 2097-2103
-
-
Schafer, K.1
Muller, K.2
Hecke, A.3
Mounier, E.4
Goebel, J.5
Loskutoff, D.6
Konstantinides, S.7
-
26
-
-
0026448949
-
Complete deficiency of plasminogen-activator inhibitor type 1 due to a frame-shift mutation
-
Fay WP, Shapiro AD, Shih JL, Schleef RR, Ginsburg D. Complete deficiency of plasminogen-activator inhibitor type 1 due to a frame-shift mutation. N Engl J Med 1992; 327: 1729-33.
-
(1992)
N Engl J Med
, vol.327
, pp. 1729-1733
-
-
Fay, W.P.1
Shapiro, A.D.2
Shih, J.L.3
Schleef, R.R.4
Ginsburg, D.5
-
27
-
-
0028807498
-
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
-
Morhman SJ, Langenbach R, Loftin CD, Tiano HF, Vouloumanos N, Jennette JC, Mahler JF, Kluckman KD, Ledford A, Lee CA, Smithies O. Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell 1995; 83: 473-82.
-
(1995)
Cell
, vol.83
, pp. 473-482
-
-
Morhman, S.J.1
Langenbach, R.2
Loftin, C.D.3
Tiano, H.F.4
Vouloumanos, N.5
Jennette, J.C.6
Mahler, J.F.7
Kluckman, K.D.8
Ledford, A.9
Lee, C.A.10
Smithies, O.11
-
28
-
-
0028818913
-
Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
-
Dinchuk JE, Car BD, Focht RJ, Johnston JJ, Jaffee BD, Covington MB, Contel NR, Eng VM, Collins RJ, Czerniak PM, Gorry SA, Trzaskos JM. Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II. Nature 1995; 378: 406-9.
-
(1995)
Nature
, vol.378
, pp. 406-409
-
-
Dinchuk, J.E.1
Car, B.D.2
Focht, R.J.3
Johnston, J.J.4
Jaffee, B.D.5
Covington, M.B.6
Contel, N.R.7
Eng, V.M.8
Collins, R.J.9
Czerniak, P.M.10
Gorry, S.A.11
Trzaskos, J.M.12
-
29
-
-
1642346949
-
A new euglobulin clot lysis assay for global fibrinolysis
-
Smith AA, Jacobson LJ, Miller BI, Hathaway WE, Manco-Jonson MJ. A new euglobulin clot lysis assay for global fibrinolysis. Thromb Res 2003; 112: 329-37.
-
(2003)
Thromb Res
, vol.112
, pp. 329-337
-
-
Smith, A.A.1
Jacobson, L.J.2
Miller, B.I.3
Hathaway, W.E.4
Manco-Jonson, M.J.5
-
30
-
-
0036155992
-
Heparin cofactor II inhibits arterial thrombosis after endothelial injury
-
He L, Vincente CP, Westnick RJ, Eitzman DT, Tollefsen DM. Heparin cofactor II inhibits arterial thrombosis after endothelial injury. J Clin Invest 2002; 109: 213-9.
-
(2002)
J Clin Invest
, vol.109
, pp. 213-219
-
-
He, L.1
Vincente, C.P.2
Westnick, R.J.3
Eitzman, D.T.4
Tollefsen, D.M.5
-
31
-
-
33845976370
-
Evidence for a pre-latent form of the serpin plasminogen activator inhibitor-1 with detached Β-strand 1C
-
Dupont DM, Blouse GE, Hansen M, Mathiasen L, Kjelgaard S, Jensen JK, Christensen A, Gils A, Declerck PJ, Andreasen PA, Wind T. Evidence for a pre-latent form of the serpin plasminogen activator inhibitor-1 with detached Β-strand 1C. J Biol Chem 2006; 281: 36071-81.
-
(2006)
J Biol Chem
, vol.281
, pp. 36071-36081
-
-
Dupont, D.M.1
Blouse, G.E.2
Hansen, M.3
Mathiasen, L.4
Kjelgaard, S.5
Jensen, J.K.6
Christensen, A.7
Gils, A.8
Declerck, P.J.9
Andreasen, P.A.10
Wind, T.11
-
32
-
-
0035075412
-
A tail vein bleeding time model and delayed bleeding in hemophiliac mice
-
Broze GJ, Yin ZF, Lasky N. A tail vein bleeding time model and delayed bleeding in hemophiliac mice. Thromb Haemost 2001; 85: 747-8.
-
(2001)
Thromb Haemost
, vol.85
, pp. 747-748
-
-
Broze, G.J.1
Yin, Z.F.2
Lasky, N.3
-
33
-
-
2442746719
-
Mouse urine collection using clear plastic wrap
-
Kurien BT, Scofield R. Mouse urine collection using clear plastic wrap. Lab Anim 1999; 33: 83-6.
-
(1999)
Lab Anim
, vol.33
, pp. 83-86
-
-
Kurien, B.T.1
Scofield, R.2
-
35
-
-
0035970022
-
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
-
Loftin CD, Trivedi DB, Tiano HF, Clark JA, Lee CA, Epstein JA, Morham SG, Breyer MD, Nguyen M, Hawkins BM, Goulet JL, Smithies O, Koller BH, Langenbach R. Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2. PNAS 2001; 98: 1059-64.
-
(2001)
PNAS
, vol.98
, pp. 1059-1064
-
-
Loftin, C.D.1
Trivedi, D.B.2
Tiano, H.F.3
Clark, J.A.4
Lee, C.A.5
Epstein, J.A.6
Morham, S.G.7
Breyer, M.D.8
Nguyen, M.9
Hawkins, B.M.10
Goulet, J.L.11
Smithies, O.12
Koller, B.H.13
Langenbach, R.14
-
36
-
-
33646415952
-
Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function
-
Cheng Y, Wang M, Yu Y, Lawson J, Funk C, FitzGerald GA. Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function. J Clin Invest 2006; 116: 1391-9.
-
(2006)
J Clin Invest
, vol.116
, pp. 1391-1399
-
-
Cheng, Y.1
Wang, M.2
Yu, Y.3
Lawson, J.4
Funk, C.5
FitzGerald, G.A.6
-
37
-
-
0023837063
-
Inter-relationships between vascular thomboxane and prostacyclin synthesis
-
James MJ, Walsh JA. Inter-relationships between vascular thomboxane and prostacyclin synthesis. Prostaglandins Leukot Essent Fatty Acids 1988; 31: 91-5.
-
(1988)
Prostaglandins Leukot Essent Fatty Acids
, vol.31
, pp. 91-95
-
-
James, M.J.1
Walsh, J.A.2
-
38
-
-
79251564713
-
2. A new group of biologically active compounds derived from prostaglandin endoperoxides
-
2. A new group of biologically active compounds derived from prostaglandin endoperoxides. Proc Natl Acad Sci USA 1975; 72: 2994.
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 2994
-
-
Moncada, S.1
Vane, J.R.2
-
39
-
-
17844404832
-
Prostaglandin E2 Promotes migration and adhesion in hepatocellular carcinoma cells
-
Fernandez-Martinez MR, Bosca A, Martin-Sanz P. Prostaglandin E2 Promotes migration and adhesion in hepatocellular carcinoma cells. Carcinogenesis 2005; 26: 753-61.
-
(2005)
Carcinogenesis
, vol.26
, pp. 753-761
-
-
Fernandez-Martinez, M.R.1
Bosca, A.2
Martin-Sanz, P.3
-
40
-
-
0031277784
-
Enhanced blood coagulation and enhanced fibrinolysis during hemodialysis with prostacyclin
-
Novacek G, Kapiotis S, Jilma B, Quehenberger P, Michitsch A, Traindl O, Speiser W. Enhanced blood coagulation and enhanced fibrinolysis during hemodialysis with prostacyclin. Thromb Res 1997; 88: 283-90.
-
(1997)
Thromb Res
, vol.88
, pp. 283-290
-
-
Novacek, G.1
Kapiotis, S.2
Jilma, B.3
Quehenberger, P.4
Michitsch, A.5
Traindl, O.6
Speiser, W.7
-
42
-
-
0027135792
-
Plasminogen activator inhibitor-1 gene-deficient mice
-
Carmeliet P, Stassen JM, Schoonjans L, Ream B, van den Oord JJ, De Mol M, Mulligan RC, Collen D. Plasminogen activator inhibitor-1 gene-deficient mice. J Clin Invest 1993; 92: 2756-60.
-
(1993)
J Clin Invest
, vol.92
, pp. 2756-2760
-
-
Carmeliet, P.1
Stassen, J.M.2
Schoonjans, L.3
Ream, B.4
van den Oord, J.J.5
De Mol, M.6
Mulligan, R.C.7
Collen, D.8
|