Ameloblastin regulates osteogenic differentiation by inhibiting Src kinase via cross talk between integrin β1 and CD63

Molecular and Cellular Biology

Volumn 31, Issue 4, 2011, Pages 783-792

  Iizuka, Shinji ^a   Kudo, Yasusei ^a   Yoshida, Maki ^a   Tsunematsu, Takaaki ^a   Yoshiko, Yuji ^a   Uchida, Takashi ^a   Ogawa, Ikuko ^b   Miyauchi, Mutsumi ^a   Takata, Takashi ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMELOBLASTIN; BETA1 INTEGRIN; CD63 ANTIGEN; PROTEIN TYROSINE KINASE;

AMELOBLAST; ANIMAL CELL; ARTICLE; BONE MINERALIZATION; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD29; BASE SEQUENCE; CELL LINE; CELL LINE, TUMOR; CELLS, CULTURED; DENTAL ENAMEL PROTEINS; DNA PRIMERS; HUMANS; MINERALS; MODELS, BIOLOGICAL; OSTEOBLASTS; OSTEOGENESIS; OSTEOSARCOMA; PLATELET MEMBRANE GLYCOPROTEINS; RATS; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 79251547685     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00912-10     Document Type: Article

References (35)

1. Anderson, H. C., et al. 2005. Sustained osteomalacia of long bones despite major improvement in other hypophosphatasia-related mineral deficits in tissue nonspecific alkaline phosphatase/nucleotide pyrophosphatase phosphodiesterase 1 double-deficient mice. Am. J. Pathol. 166:1711-1720.
2. Berditchevski, F. 2001. Complexes of tetraspanins with integrins: more than meets the eye. J. Cell Sci. 114:4143-4151. (Pubitemid 33138652)
3. Dahl, L. K. 1952. A simple and sensitive histochemical method for calcium. Proc. Soc. Exp. Biol. Med. 80:474-479.
4. Cerný, R., I. Slaby, L. Hammarström, and T. Wurtz. 1996. A novel gene expressed in rat ameloblasts codes for proteins with cell binding domains. J. Bone Miner. Res. 11:883-891.
5. Fong, C. D., I. Slaby, and L. Hammarström. 1996. Amelin: an enamel-related protein, transcribed in the cells of epithelial root sheath. J. Bone Miner. Res. 11:892-898.
6. Foster, L. J., P. A. Zeemann, C. Li, M. Mann, O. N. Jensen, and M. Kassem. 2005. Differential expression profiling of membrane proteins by quantitative proteomics in a human mesenchymal stem cell line undergoing osteoblast differentiation. Stem Cells 23:1367-1377.
7. Fukumoto, S., et al. 2004. Ameloblastin is a cell adhesion molecule required for maintaining the differentiation state of ameloblasts. J. Cell Biol. 167:973-983. (Pubitemid 39628119)
8. Gordon, J. A., et al. 2007. Bone sialoprotein expression enhances osteoblast differentiation and matrix mineralization in vitro. Bone 41:462-473.
9. Goschnick, M. W., and D. E. Jackson. 2007. Tetraspanins-structural and signalling scaffolds that regulate platelet function. Mini Rev. Med. Chem. 7:1248-1254.
10. Iwata, T., et al. 2007. Processing of ameloblastin by MMP-20. J. Dent. Res. 86:153-157.
11. Jikko, A., S. E. Harris, D. Chen, D. L. Mendrick, and C. H. Damsky. 1999. Collagen integrin receptors regulate early osteoblast differentiation induced by BMP-2. J. Bone Miner. Res. 14:1075-1083.
12. Jung, K. K., X. W. Liu, R. Chirco, R. Fridman, and H. R. Kim. 2006. Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein. EMBO J. 25:3934-3942.
13. Kawasaki, K., and K. M. Weiss. 2003. Mineralized tissue and vertebrate evolution: the secretory calcium-binding phosphoprotein gene cluster. Proc. Natl. Acad. Sci. U. S. A. 100:4060-4065.
14. Krebsbach, P. H., et al. 1996. Full-length sequence, localization, and chromosomal mapping of ameloblastin. A novel tooth-specific gene. J. Biol. Chem. 271:4431-4435.
15. Lin, D., et al. 2008. Expression of tetraspan protein CD63 activates protein-tyrosine kinase (PTK) and enhances the PTK-induced inhibition of ROMK channels. J. Biol. Chem. 283:7674-7681.
16. Mantegazza, A. R., et al. 2004. CD63 tetraspanin slows down cell migration and translocates to the endosomal-lysosomal-MIICs route after extracellular stimuli in human immature dendritic cells. Blood 104:1183-1190.
17. Marzia, M., Sims, et al. 2000. Decreased c-Src expression enhances osteoblast differentiation and bone formation. J. Cell Biol. 151:311-320.
18. MacDougall, M. 2003. Dental structural diseases mapping human chromosome 4q21. Connect. Tissue Res. 44:285-291.
19. Müller, W. E., et al. 2007. Morphogenetic activity of silica and bio-silica on the expression of genes controlling biomineralization using SaOS-2 cells. Calcif. Tissue Int. 81:382-393.
20. Ozdemir, D., et al. 2005. MMP20 active-site mutation in hypomaturation amelogenesis imperfecta. J. Dent. Res. 84:1031-1035.
21. Ravindranath, R. M., A. Devarajan, and T. Uchida. 2007. Spatiotemporal expression of ameloblastin isoforms during murine tooth development. J. Biol. Chem. 282:36370-36376.
22. Roskoski, R., Jr. 2004. Src protein-tyrosine kinase structure and regulation. Biochem. Biophys. Res. Commun. 324:1155-1164.
23. Roskoski, R., Jr. 2005. Src kinase regulation by phosphorylation and dephosphorylation. Biochem. Biophys. Res. Commun. 331:1-14.
24. Soriano, P., C. Montgomery, R. Geske, and A. Bradley. 1991. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64:693-702. (Pubitemid 121001157)
25. Spahr, A., S. P. Lyngstadaas, I. Slaby, and G. Pezeshki. 2006. Ameloblastin expression during craniofacial bone formation in rats. Eur. J. Oral Sci. 114:504-511.
26. Stipp, C. S., T. V. Kolesnikova, and M. E. Hemler. 2003. Functional domains in tetraspanin proteins. Trends Biochem. Sci. 28:106-112.
27. Takeuchi, Y., et al. 1997. Differentiation and transforming growth factor-b receptor down-regulation by collagen-α2β1 integrin interaction is mediated by focal adhesion kinase and its downstream signals in murine osteoblastic cells. J. Biol. Chem. 272:29309-29316.
28. Tsunematsu, T., et al. 2009. RUNX3 has an oncogenic role in head and neck cancer. PLoS One 4:e5892.
29. Wang, H., S. Tannukit, D. Zhu, M. L. Snead, and M. L. Paine. 2005. Enamel matrix protein interactions. J. Bone Miner. Res. 20:1032-1040.
30. Wazen, R. M., P. Moffatt, S. F. Zalzal, Y. Yamada, and A. Nanci. 2009. A mouse model expressing a truncated form of ameloblastin exhibits dental and junctional epithelium defects. Matrix Biol. 28:292-303.
31. Xiao, G., D. Wang, M. D. Benson, G. Karsenty, and R. T. Franceschi. 1998. Role of the α2-integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor. J. Biol. Chem. 273:32988-32994.
32. Yunta, M., and P. A. Lazo. 2003. Tetraspanin proteins as organisers of membrane microdomains and signalling complexes. Cell Signal. 15:559-564.
33. Zaidi, S. K., et al. 2004. Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription. EMBO J. 23:790-799.
34. Zeichner-David, M., et al. 2006. Amelogenin and ameloblastin show growth-factor like activity in periodontal ligament cells. Eur. J. Oral Sci. 114:244-253.
35. Zou, Y., et al. 2007. Determination of protein regions responsible for interactions of amelogenin with CD63 and LAMP1. Biochem. J. 408:347-354.