Overestimated frequency of a possible emphysema-susceptibility allele when microsomal epoxide hydrolase is genotyped by the conventional polymerase chain reaction-based method

Journal of Human Genetics

Volumn 46, Issue 2, 2001, Pages 96-98

  Keicho, N ^a   Emi, M ^b   Kajita, M ^b   Matsushita, I ^a   Nakata, K ^a   Azuma, A ^b   Ohishi, N ^c   Kudoh, S ^b  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b NIPPON MEDICAL SCHOOL   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Emphysema; Genotyping; Microsomal epoxide hydrolase; Restriction fragment length polymorphism; Single stranded conformation polymorphism

Indexed keywords

EPOXIDE HYDROLASE;

ARTICLE; EMPHYSEMA; ENZYME ACTIVITY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEQUENCE ANALYSIS; SINGLE STRAND CONFORMATION POLYMORPHISM; TISSUE DISTRIBUTION;

EID: 0035085353     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100380170116     Document Type: Article

References (8)

1. Molecular genetics of chronic obstructive pulmonary disease
2. Association of diffuse panbronchiolitis with microsatellite polymorphism at the human interleukin 8 (IL-8) locus
3. Human microsomal epoxide hydrolase: Genetic polymorphism and functional expression in vitro of amino acid variants
4. Five familial hypercholesterolemic kindreds in Japan with novel mutation of the LDL receptor gene
5. Association between polymorphism in the gene for microsomal epoxide hydrolase and susceptibility to emphysema
6. Isolation and mapping of a polymorphic CA repeat sequence at the human interleukin 6 locus
7. Isolation and radiation hybrid mapping of dinucleotide repeat polymorphism at the human matrix Gla protein (MGP) locus