Preparation and in vitro antibacterial evaluation of gatifloxacin mucoadhesive gellan system

DARU, Journal of Pharmaceutical Sciences

Volumn 18, Issue 4, 2010, Pages 237-246

  Kesavan, K ^a   Nath, G ^b   Pandit, J K ^a  

^a BANARAS HINDU UNIVERSITY   (India)

^b BANARAS HINDU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIVE AGENT; ALGINIC ACID; CARBOXYMETHYLCELLULOSE; GATIFLOXACIN; GELLAN;

ADHESION; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL COUNT; DRUG FORMULATION; DRUG RELEASE; ESCHERICHIA COLI; FLOW KINETICS; GELATION; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STAPHYLOCOCCUS AUREUS;

EID: 79251516389     PISSN: 15608115     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Lee VHL, Robinson JR. Mechanistic and quantitative evaluation of precorneal pilocarpine disposition in albino rabbits. J Pharm Sci, 1979; 68: 673-684.
2. Maurice DM, Mishima S. Ocular pharmacokinetics. In: M.C. Sears (Ed.), Handbook of Experimental Pharmacology. Pharmacology of the Eye. Vol. 69, Springer-Verlag, Berlin-Heidelberg, 1984; pp. 19-116.
3. Bourlais CL, Acar L, Zia H, Sado PA, Needham T, Leverge R. Ophthalmic drug delivery systems-recent advance. Prog Retinal Eye Res, 1998; 17: 33-58.
4. Ding S. Recent developments in ophthalmic drug delivery. Pharm Sci Technol Today, 1998; 1: 328-335.
5. Hill JM, O'Callaghan RJ, Hobden JA, Kaufman H.E. Corneal collagen shields for ocular drug delivery. In: Mitra AK., ed. Ophthalmic Drug Delivery Systems, Dekker, New York, 1993, 261-275.
6. Marriott C, Gregory NP. Mucus Physiology and Pathology, Bioadhesive Drug Delivery Systems, in: V. Lenaerts, Gurny (Eds.), CRC, Boca Raton, 1990, pp. 1-24.
7. Nagai T, Machida Y. Mucosal adhesive dosage forms. Pharm Int, 1985; 6: 196-200.
8. Kamath KR, Park K. Mucosal adhesive preparations, in Encyclopedia of Pharmaceutical Technology; J. Swarbrick and J. C. Boylan, eds., Vol. 10 Marcel Dekker, New York, 1994; 133.
9. Hwang DG. Fluoroquinolone resistance in ophthalmology and the potential role for newer ophthalmic fluoroquinolones. Surv Ophthalmol, 2004; 49: S79-S83.
10. Hartmann V, Keipert S. Physico-chemical, in vitro and in vivo characterisation of polymers for ocular use. Pharmazie, 2000; 55: 440-443.
11. Mishra DN, Gilhotra R.M, Design and characterization of bioadhesive in-situ gelling ocular inserts of gatifloxacin sesquihydrate. DARU, 2008; 16: 1-8.
12. Hassan EE, Gallo J.M. A simple rheological method for the in vitro assessment of mucin-polymer bioadhesive bond strength. Pharm Res, 1990; 7: 491-495.
13. Srividya B, Cardoza RM, Amin PD. Sustained ophthalmic delivery of ofloxacin from a pH triggered in situ gelling system. J Control Release, 2001; 73: 205-211.
14. Gibaldi M, Feldman S. Establishment of sink conditions in dissolution rate determinations. Theoretical considerations and application to non-disintegrating dosage forms. J Pharm Sci, 1967; 56: 1238-1242.
15. Wagner JG. Interpretation of percent dissolved-time plots derived from in vitro testing of conventional tablets and capsules. J Pharm Sci, 1969; 58: 1253-1257.
16. Higuchi T. Mechanism of sustained action medication: theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J Pharm Sci, 1963; 52: 1145-1149.
17. Korsmeyer R.W, Gurny R, Doelker E.M, Buri P, Peppas N.A. Mechanisms of solute release from porous hydrophilic polymers. Int J Pharm, 1983; 15: 25-35.
18. Peppas NA. Analysis of Fickian and non-Fickian drug release polymers. Pharm Acta Helv, 1985; 60: 110-11.
19. Jeong YI, Na HS, Seo D.H, Kim DG, Lee HC, Jang MK, Na SK, Roh SH, Kim SI, Na JW. Ciprofloxacin-encapsulated poly (DL-lactide-co-glycolide) nanoparticles and its antibacterial activity. Int J Pharm, 2008; 352: 317-323.
20. Balasubramaniam J, Pandit JK. Ion-activated in situ gelling systems for sustained ophthalmic delivery of ciprofloxacin hydrochloride. Drug Deliv, 2003; 10: 185-191.
21. Van Ootegham MM. In Biopharmaceutics of Ocular Drug Delivery, ed. P. Edman, Boca Raton, FL: CRC Press, 1993, 27-41.
22. Bothner H, Waaler T, Wik O. Rheological characterization of tear substitutes. Drug Dev Ind Pharm, 1990; 16: 755-768.
23. Gu J, Robinson JR, Leung S. Binding of acrylic polymers to mucin/epithelial surfaces: structure property-relationships. Crit Rev Ther Drug Carrier Syst, 1988; 5: 21-67.
24. Bohdanecky M, Kvar J. In A.D. Jenkins (ed.), Viscosity of polymer solution, Polymer Science Library 2, Elsevier Scientific, Amsterdam-Oxford-New York, 1982.
25. Peppas NA, Buri PA. Surface, interfacial and molecular aspects of bioadhesion on soft tissues. J Control Release, 1985; 2: 257-275.
26. Paulsson M, Hägerström H, Edsman K. Rheological studies of the gelation of deacetylated gellan gum (GelriteR) in physiological conditions, Eur J Pharm Sci, 1999; 9: 99-105.
27. Rozier A, Mazuel C, Grove J, Plazonnet B. Functionality testing of gellan gum, a polymeric excipient material for ophthalmic dosage form, Int J Pharm, 1997; 153: 191-198.
28. Chen H.B, Yamabayashi S, Ou B, Tanaka Y, Ohno S, Tsukahara S. Structure and composition of rat precorneal tear film. A study by an in vivo cryofixation. Invest Ophthalmol Vis Sci, 1997; 38: 381-387.
29. Mansour M, Mansour S, Mortada ND, Abd Elhady SS. Ocular poloxamer-based ciprofloxacin hydrochloride in situ forming gels. Drug Dev Ind Pharm, 2008; 34: 744-752.
30. Séchoy O, Tissié G, Sébastian C, Maurin F, Driot JY, Trinquand C. A new long acting ophthalmic formulation of carteolol containing alginic acid. Int J Pharm, 2000; 207: 109-116.
31. Kanesaka S, Watanabe T, Matsukawa S. Binding effect of Cu2+ as a trigger on the sol-to-gel and the coil-to-helix transition processes of polysaccharide, gellan gum. Biomacromolec, 2004; 5: 863-868.
32. Larsen B, Smidsrød O, Painter T, Haug A. Calculation of the nearest-neighbour frequencies in fragments of alginate from the yields of free monomers after partial hydrolysis. Acta Chem Scand, 1970; 24: 726-728.