Local control after craniospinal irradiation, intensity-modulated radiotherapy boost, and chemotherapy in childhood medulloblastoma

Cancer

Volumn 117, Issue 3, 2011, Pages 635-641

  Paulino, Arnold C ^a,b   Mazloom, Ali ^a   Teh, Bin S ^a   South, Michael ^a   Okcu, M Fatih ^b   Su, Jack ^b   Butler, E Brian ^a   Chintagumpala, Murali ^b  

^a HOUSTON METHODIST HOSPITAL   (United States)

^b TEXAS CHILDREN S HOSPITAL   (United States)

Author keywords

intensity modulated radiotherapy; local control; medulloblastoma; pediatric brain tumor; radiotherapy

Indexed keywords

CISPLATIN;

ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANCER CONTROL; CANCER RISK; CANCER SURGERY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HIGH RISK PATIENT; HUMAN; INTENSITY MODULATED RADIATION THERAPY; MALE; MEDULLOBLASTOMA; OVERALL SURVIVAL; POSTERIOR FOSSA; PRESCHOOL CHILD; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RADIATION DOSE; RISK ASSESSMENT; TREATMENT FAILURE;

ADOLESCENT; CEREBELLAR NEOPLASMS; CHEMOTHERAPY, ADJUVANT; CHILD; CHILD, PRESCHOOL; COMBINED MODALITY THERAPY; CRANIAL IRRADIATION; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MEDULLOBLASTOMA; RADIOTHERAPY, INTENSITY-MODULATED; TREATMENT FAILURE;

EID: 79251490708     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.25601     Document Type: Article

References (25)

1. Gajjar A, Chintagumpala M, Ashley D, et al. Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St. Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial. Lancet Oncol. 2006; 7: 813-820.
2. Packer RJ, Gajjar A, Vezina G, et al. Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma. J Clin Oncol. 2006; 24: 4202-4208.
3. Zeltzer PM, Boyett JM, Finlay JL, et al. Metastasis stage, adjuvant treatment, and residual tumor are prognostic factors for medulloblastoma in children: conclusions from the Children's Cancer Group 921 randomized phase III study. J Clin Oncol. 1999; 17: 832-845.
4. Paulino AC, Narayana A, Mohideen MN, Jeswani S., Posterior fossa boost in medulloblastoma: an analysis of dose to surrounding structures using 3-dimensional (conformal) radiotherapy. Int J Radiat Oncol Biol Phys. 2000; 46: 281-286.
5. Michalski JM, Sur RK, Harms WB, Purdy JA., Three dimensional conformal radiation therapy for pediatric parameningeal rhabdomyosarcoma. Int J Radiat Oncol Biol Phys. 1995; 33: 985-991.
6. Teh BS, Woo SY, Butler EB., Intensity modulated radiation therapy (IMRT): a new promising technology in radiation oncology. Oncologist. 1999; 4: 433-442.
7. Paulino AC, Skwarchuk M., Intensity-modulated radiation therapy in the treatment of children. Med Dosim. 2002; 27: 115-120.
8. Huang E, Teh BS, Strother DR, et al. Intensity-modulated radiation therapy for pediatric medulloblastoma: early report on the reduction of ototoxicity. Int J Radiat Oncol Biol Phys. 2003; 52: 599-605.
9. Merchant TE, Kun LE, Krasin MJ, et al. Multi-institution prospective trial of reduced-dose craniospinal irradiation (23.4 Gy) followed by conformal posterior fossa (36 Gy) and primary site irradiation (55.8 Gy) and dose-intensive chemotherapy for average-risk medulloblastoma. Int J Radiat Oncol Biol Phys. 2008; 70: 782-787.
10. Merchant TE, Happersett L, Finlay JL, Leibel SA., Preliminary results of conformal radiation therapy for medulloblastoma. Neuro-Oncology. 1999; 1: 177-187.
11. Wolden SL, Dunkel IJ, Souweidane MM, et al. Patterns of failure using a conformal radiation therapy tumor bed boost for medulloblastoma. J Clin Oncol. 2003; 21: 3079-3083.
12. Douglas JG, Barker JL, Ellenbogen RG, Geyer JR., Concurrent chemotherapy and reduced-dose cranial spinal irradiation followed by conformal posterior fossa tumor bed boost for average-risk medulloblastoma: efficacy and patterns of failure. Int J Radiat Oncol Biol Phys. 2004; 58: 1161-1164.
13. Robertson PL, Muraszko KM, Holmes EJ, et al. Incidence and severity of postoperative cerebellar mutism syndrome in children with medulloblastoma: a prospective study by the Children's Oncology Group. J Neurosurg. 2006; 105 (6 suppl): 444-451.
14. Laughton SJ, Merchant TE, Sklar CA, et al. Endocrine outcomes for children with embryonal tumors after risk-adapted craniospinal and conformal primary-site irradiation and high-dose chemotherapy with stem-cell rescue. J Clin Oncol. 2008; 26: 1112-1118.
15. South M, Chiu JK, Teh BS, Bloch C, Schroeder TM, Paulino AC., Supine craniospinal irradiation using intrafractional junction shifts and field-in-field dose shaping: early experience at Methodist Hospital. Int J Radiat Oncol Biol Phys. 2008; 71: 477-483.
16. Chao KS, Ozygit G, Tran BN, Cengiz M, Dempsey JF, Low DA., Patterns of failure in patients receiving definitive and postoperative IMRT for head-and-neck cancer. Int J Radiat Oncol Biol Phys. 2003; 55: 312-321.
17. Carrie C, Grill J, Figarella-Branger D, et al. Online quality control, hyperfractionated radiotherapy alone and reduced boost volume for standard risk medulloblastoma: long-term results of MSFOP 98. J Clin Oncol. 2009; 27: 1879-1883.
18. Polkinghorn WR, Dunkel IJ, Souweidane MM, et al. Outcomes using IMRT tumor-bed boost for medulloblastoma [abstract]. Int J Radiat Oncol Biol Phys. 2008; 72 (suppl): 79-80.
19. Khafaga Y, Kandil AE, Jamshed A, Hassounah M, Devol E, Gray AJ., Treatment results for 149 medulloblastoma patients from 1 institution. Int J Radiat Oncol Biol Phys. 1996; 35: 501-506.
20. Silverman CL, Simpson JR., Cerebellar medulloblastoma: the importance of posterior fossa dose to survival and patterns of failure. Int J Radiat Oncol Biol Phys. 1982; 8: 1869-1876.
21. Del Charco JO, Bolek TW, McCollough WM, et al. Medulloblastoma: time-dose relationship based on a 30-year review. Int J Radiat Oncol Biol Phys. 1998; 42: 147-154.
22. Merchant TE, Wang MH, Haida T, et al. Medulloblastoma: long-term results for patients treated with definitive radiation therapy during the computed tomography era. Int J Radiat Oncol Biol Phys. 1996; 36: 29-35.
23. Taylor RE, Bailey CC, Robinson KJ, et al. Impact of radiotherapy parameters on outcome in the International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 study of preradiotherapy chemotherapy for M0-M1 medulloblastoma. Int J Radiat Oncol Biol Phys. 2004; 58: 1184-1193.
24. Paulino AC, Lobo M, Teh BS, et al. Ototoxicity after intensity-modulated radiation therapy and cisplatin-based chemotherapy in children with medulloblastoma [published online ahead of print March 13, 2010]. Int J Radiat Oncol Biol Phys. 2010.
25. Jain N, Krull KR, Brouwers P, Chintagumpala MM, Woo SY., Neuropsychological outcome following intensity-modulated radiation therapy for pediatric medulloblastoma. Pediatr Blood Cancer. 2008; 51: 275-279.