Incidence and severity of postoperative cerebellar mutism syndrome in children with medulloblastoma: A prospective study by the Children's Oncology Group

Journal of Neurosurgery

Volumn 105 PEDIATRICS, Issue SUPPL. 6, 2006, Pages 444-451

  Robertson, Patricia L ^a   Muraszko, Karin M ^b   Holmes, Emiko J ^b   Sposto, Richard ^b   Packer, Roger J ^b   Gajjar, Amar ^b   Dias, Mark S ^b   Allen, Jeffrey C ^b  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b NONE

Author keywords

Brain tumor; Cerebellar mutism syndrome; Medulloblastoma; Pediatric neurosurgery; Posterior fossa; Pseudobulbar syndrome; Resection

Indexed keywords

CISPLATIN; CYCLOPHOSPHAMIDE; ETOPOSIDE; LOMUSTINE; VINCRISTINE;

ARTICLE; ASEPTIC MENINGITIS; ATAXIA; BRAIN STEM; CANCER RADIOTHERAPY; CENTRAL NERVOUS SYSTEM INFECTION; CEREBELLUM CORTEX; CHILD; CLINICAL FEATURE; CLINICAL TRIAL; COGNITIVE DEFECT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEMOGRAPHY; DISEASE SEVERITY; FEMALE; HEALTH SURVEY; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MEDICAL INFORMATION; MEDULLOBLASTOMA; MUTISM; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUESTIONNAIRE; RADIATION DOSE; RISK FACTOR; SPEECH DISORDER; TREATMENT OUTCOME;

EID: 33845688236     PISSN: 00223085     EISSN: 00223085     Source Type: Journal    
DOI: 10.3171/ped.2006.105.6.444     Document Type: Article

References (76)

1. Adams RD, Victor M (eds): The Cerebellum, in Principles of Neurology, ed 5. New York: McGraw-Hill, 1993, pp 874-882
2. Aguiar PH, Plese JP, Ciquini O, Marino R: Transient mutism following a posterior fossa approach to cerebellar tumors in children: a critical review of the literature. Childs Nerv Syst 11:306-310, 1995
3. Al-Anazi A, Hassounah M, Sheikh B, Barayan S: Cerebellar mutism caused by arteriovenous malformation of the vermis. Br J Neurosurg 15:47-50, 2001
4. al-Jarallah A, Cook JD, Gascon G, Kanaan I, Sigueira E: Transient mutism following posterior fossa surgery in children. J Surg Oncol 55:126-131, 1994
5. Albright AL, Sposto R, Holmes E, Zeltzer PM, Finlay JL, Wisoff JH, et al: Correlation of neurosurgical subspecialization with outcomes in children with malignant brain tumors. Neurosurgery 47:879-887, 2000
6. Albright AL, Wisoff JH, Zeltzer PM, Boyett JM, Rorke LB, Stanley P: Effects of medulloblastoma resections on outcome in children: a report from the Children's Cancer Group. Neurosurgery 38:265-271, 1996
7. Allen G, Buxton RB, Wong EC, Courchesne E: Attentional activation of the cerebellum independent of motor involvement. Science 275:1940-1943, 1997
8. Ammirati M, Mirzai S, Samii M: Transient mutism following removal of a cerebellar tumor. A case report and review of the literature. Childs Nerv Syst 5:12-14, 1989
9. Asamoto M, Ito H, Suzuki N, Oiwa Y, Saito K, Haraoka J: Transient mutism after posterior fossa surgery. Childs Nerv Syst 10:275-278, 1994
10. Berman AJ, Berman D, Prescott JW: The effect of cerebellar lesions on emotional behavior in the rhesis monkey, in Cooper IS, Riklan M, Snider RS (eds): The Cerebellum, Epilepsy, and Behavior. New York: Plenum Press, 1978, p 284
11. Bhatoe HS: Mutism, oropharyngeal apraxia and dysarthria after posterior fossa tumor excision. Br J Neurosurg 11:341-343, 1997
12. Cakir Y, Karakisi D, Kocanaogullari O: Cerebellar mutism in an adult: case report. Surg Neurol 41:342-344, 1994
13. Catsman-Berrevoets CE, Van Dongen HR, Mulder PGH, Paz y Geuze D, Paquier PF, Lequin MH: Tumour type and size are high risk factors for the syndrome of "cerebellar" mutism and subsequent dysarthria. J Neurol Neurosurg Psychiatry 67:755-757, 1999
14. Catsman-Berrevoets CE, van Dongen HR, Zwetsloot CP: Transient loss of speech followed by dysarthria after removal of posterior fossa tumor. Dev Med Child Neurol 34:1102-1109, 1992
15. Cochrane DD, Gustavsson B, Poskitt KP, Steinbok P, Kestle JR: The surgical and natural morbidity of aggressive resection for posterior fossa tumors in childhood. Pediatr Neurosurg 20:19-29, 1994
16. Crutchfield JS, Sawaya R, Meyers CA, Moore BD III: Postoperative mutism in neurosurgery. Report of two cases. J Neurosurg 81:115-121, 1994
17. D'Avanzo R, Scuotto A, Natale M, Scotto P, Cioffi FA: Transient "cerebellar" mutism in lesions of the mesencephalic-cerebellar region. Acta Neurol (Napoli) 15:289-296, 1993
18. Dailey AT, McKhann GM II, Berger MS: The pathophysiology of oral pharyngeal apraxia and mutism following posterior fossa tumor resection in children. J Neurosurg 83:467-475, 1995
19. Dietze DD Jr, Mickle JP: Cerebellar mutism after posterior fossa surgery. Pediatr Neurosurg 16:25-31, 1990/1991
20. Doxey D, Bruce D, Sklar F, Swift D, Shapiro K: Posterior fossa syndrome: identifiable risk factors and irreversible complications. Pediatr Neurosurg 31:131-136, 1999
21. Dunwoody GW, Alsagoff ZS, Yuan SY: Cerebellar mutism with subsequent dysarthria in an adult: case report. Br J Neurosurg 11:161-163, 1997
22. Ersahin Y, Mutluer S, Çagli S, Duman Y: Cerebellar mutism: report of seven cases and review of the literature. Neurosurgery 38:60-66, 1996
23. Ersahin Y, Mutluer S, Saydam S, Barcin E: Cerebellar mutism: report of two unusual cases and review of the literature. Clin Neurol Neurosurg 99:130-134, 1997
24. Ersahin Y, Yararbas Ü, Duman Y, Mutluer S: Single photon emission tomography following posterior fossa surgery in patients with and without mutism. Childs Nerv Syst 18:318-325, 2002
25. Ferrante L, Mastronardi L, Acqui M, Fortuna A: Mutism after posterior fossa surgery in children. Report of three cases. J Neurosurg 72:959-963, 1990
26. Fiez JA, Petersen SE, Cheney MK, Raichle ME: Impaired nonmotor learning and error detection associated with cerebellar damage. A single case study. Brain 115:155-178, 1992
27. Fraioli B, Guidetti B: Effects of stereotactic lesions of the pulvinar and lateralis posterior nucleus on intractable pain and dyskinetic syndromes of man. Appl Neurophysiol 38:23-30, 1975
28. Frim DM, Ogilvy CS: Mutism and cerebellar dysarthria after brain stem surgery: case report. Neurosurgery 36:854-857, 1995
29. Gao JH, Parsons LM, Bower JM, Xiong J, Li J, Fox PT: Cerebellum implicated in sensory acquisition and discrimination rather than motor control. Science 272:545-547, 1996
30. Gaskill SJ, Marlin AE: Transient eye closure after posterior fossa tumor surgery in children. Pediatr Neurosurg 17:196-198, 1991/1992
31. Gelabert-González M, Fernández-Villa J: Mutism after posterior fossa surgery. Review of the literature. Clin Neurol Neurosurg 103:111-114, 2001
32. Germanò A, Baldari S, Caruso G, Caffo M, Montemagno G, Cardia E, et al: Reversible cerebral perfusion alterations in children with transient mutism after posterior fossa surgery. Childs Nerv Syst 14:114-119, 1998
33. Gordon N: Speech, language, and the cerebellum. Eur J Disord Commun 31:359-367, 1996
34. Herb E, Thyen U: Mutism after cerebellar medulloblastoma surgery. Neuropediatrics 23:144-146, 1992
35. Hirsch JF, Renier D, Czernichow P, Benveniste L, Pierre-Kahn A: Medulloblastoma in childhood. Survival and functional results. Acta Neurochir (Wien) 48:1-15, 1979
36. Humphreys RP: Mutism after posterior fossa surgery, in Marlin AE (ed): Concepts in Pediatric Neurosurgery. Basel: Karger, 1989, pp 57-64
37. Ìldan F, Tuna M, Erman T, Göçer AI, Zeren M, Çetinalp E: The evaluation and comparison of cerebellar mutism in children and adults after posterior fossa surgery: report of two adult cases and review of the literature. Acta Neurochir (Wien) 144:463-473, 2002
38. Janssen G, Messing-Jünger AM, Engelbrecht V, Göbel U, Bock WJ, Lenard HG: Cerebellar mutism syndrome. Klin Padiatr 210:243-247, 1998
39. Jones S, Kirollos RW, Van Hille PT: Cerebellar mutism following posterior fossa tumor surgery. Br J Neurosurg 10:221-224, 1996
40. Kai Y, Kuratsu J, Suginohara K, Marubayashi T, Ushio Y: Cerebellar mutism after posterior fossa surgery - two case reports. Neurol Med Chir (Tokyo) 37:929-933, 1997
41. Kawai H, Ohta F, Matsumoto Y, Yamamoto Y: [An adult case of cerebellar mutism after removal of cerebellar hematoma.] No To Shinkei 53:475-479, 2001 (Jpn)
42. Kellogg JX, Piatt JH Jr: Resection of fourth ventricle tumors without splitting the vermis: the cerebellomedullary fissure approach. Pediatr Neurosurg 27:28-33, 1997
43. Kim SG, Ugurbil K, Strick PL: Activation of a cerebellar output nucleus during cognitive processing. Science 265:949-951, 1994
44. Kingma A, Mooij JJ, Metzemaekers JD, Leeuw JA: Transient mutism and speech disorders after posterior fossa surgery in children with brain tumors. Acta Neurochir (Wien) 131:74-79, 1994
45. Koh S, Turkel SB, Baram TZ: Cerebellar mutism in children: report of six cases and potential mechanisms. Pediatr Neurol 16:218-219, 1997
46. Lechtenberg R, Gilman S: Speech disorders in cerebellar disease. Ann Neurol 3:285-290, 1978
47. Liu GT, Phillips PC, Molloy PT, Needle MN, Galetta SL, Balcer LJ, et al: Visual impairment associated with mutism after posterior fossa surgery in children. Neurosurgery 42:253-257, 1998
48. Mastronardi L: Mutism and pseudobulbar symptoms after resection of posterior fossa tumors in children: incidence and pathophysiology and transient cerebellar mutism after posterior fossa surgery in children. Neurosurgery 38:1066, 1996 (Letter)
49. Middleton FA, Strick PL: Anatomical evidence for cerebellar and basal ganglia involvement in higher cognitive function. Science 266:458-461, 1994
50. Miyakita Y, Taguchi Y, Sakakibara Y, Matsuzawa M, Kitagawa H: Transient mutism resolving into cerebellar speech after brain stem infarction following a traumatic injury of the vertebral artery in a child. Acta Neurochir (Wien) 141:209-213, 1999
51. Nagatani K, Waga S, Nakagawa Y: Mutism after removal of a vermian medulloblastoma: cerebellar mutism. Surg Neurol 36:307-309, 1991
52. Nishikawa M, Komiyama M, Sakamoto H, Yasui T, Nakajima H: Cerebellar mutism after basilar artery occlusion - case report. Neurol Med Chir (Tokyo) 38:569-573, 1998
53. Oiwa Y, Ito H, Suzuki N, Otsubo Y: Cerebellar mutism after posterior fossa surgery. Childs Nerv Syst 9:363, 1993 (Abstract)
54. Orioli PJ, Strick PL: Cerebellar connections with the motor cortex and the arcuate premotor area: an analysis employing retrograde transneuronal transport of WGA-HRP. J Comp Neurol 288:612-626, 1989
55. Peters M, Monjan AA: Behavior after cerebellar lesions in cats and monkeys. Physiol Behav 6:205-206, 1971
56. Pollack IF, Polinko P, Albright AL, Towbin R, Fitz C: Mutism and pseudobulbar symptoms after resection of posterior fossa tumors in children: incidence and pathophysiology. Neurosurgery 37:885-893, 1995
57. Rekate HL, Grubb RL, Aram DM, Hahn JF, Ratcheson RA: Muteness of cerebellar origin. Arch Neurol 42:697-698, 1985
58. Ross MK, Reeves AG, Roberts DW: Postcommissurotomy mutism. Ann Neurol 16:114, 1984 (Abstract)
59. Rostomily RC, Berger MS, Ojemann GA, Lettich E: Postoperative deficits and functional recovery following removal of tumors involving the dominant hemisphere supplementary motor area. J Neurosurg 75:62-68, 1991
60. Sagiuchi T, Ishii K, Aoki Y, Kan S, Utsuki S, Tanaka R, et al: Bilateral crossed cerebello-cerebral diaschisis and mutism after surgery for cerebellar medulloblastoma. Ann Nucl Med 15:157-160, 2001
61. Salvati M, Cervoni L, Santoro A: Cerebellar mutism after posterior cranial fossa surgery. J Neurosurg Sci 40:59-63, 1996
62. Salvati M, Missori P, Lunardi P, Orlando ER: Transient cerebellar mutism after posterior cranial fossa surgery in an adult. Case report and review of the literature. Clin Neurol Neurosurg 93:313-316, 1991
63. Schmahmann JD, Sherman JC: Cerebellar cognitive affective syndrome. Int Rev Neurobiol 41:433-440, 1997
64. Siffert J, Allen J, Epstein F: The posterior fossa syndrome following tumor resection: incidence, clinical features and long-term outcome. Ann Neurol 38:553, 1995 (Abstract)
65. Siffert J, Young Poussaint T, Goumnerova LC, Scott RM, La-Valley B, Tarbell NJ, et al: Neurological dysfunction associated with postoperative cerebellar mutism. J Neurooncol 48:75-81, 2000
66. Sinha AK, Rajender Y, Dinakar I: Transient cerebellar mutism after evacuation of a spontaneous vermian haematoma. Childs Nerv Syst 14:460-462, 1998
67. Tait DM, Thornton-Jones H, Bloom HJ, Lemerle J, Morris-Jones P: Adjuvant chemotherapy for medulloblastoma: the first multi-centre control trial of the International Society of Paediatric Oncology (SIOP I). Eur J Cancer 26:464-469, 1990
68. Turgut M: Transient "cerebellar" mutism. Childs Nerv Syst 14:161-166, 1998
69. Van Calenbergh F, Van de Laar A, Plets C, Goffin J, Casaer P: Transient cerebellar mutism after posterior fossa surgery in children. Neurosurgery 37:894-898, 1995
70. Vandeinse D, Hornyak JE: Linguistic and cognitive deficits associated with cerebellar mutism. Pediatr Rehabil 1:41-44, 1997
71. van Dongen HR, Catsman-Berrevoets CE, van Mourik M: The syndrome of 'cerebellar' mutism and subsequent dysarthria. Neurology 44:2040-2046, 1994
72. Volcan I, Cole GP, Johnston K: A case of muteness of cerebellar origin. Arch Neurol 43:313-314, 1986
73. Wang MC, Winston KR, Breeze RE: Cerebellar mutism associated with a midbrain cavernous malformation. Case report and review of the literature. J Neurosurg 96:607-610, 2002
74. Wisoff JH, Epstein FJ: Pseudobulbar palsy after posterior fossa operation in children. Neurosurgery 15:707-709, 1984
75. Woo C, Stea B, Lulu B, Hamilton A, Cassady JR: The use of stereotactic radiosurgical boost in the treatment of medulloblastomas. Int J Radiat Oncol Biol Phys 37:761-764, 1997
76. Yokota H, Nakazawa S, Kobayashi S, Taniguchi Y, Yukihide T: [Clinical study of two cases of traumatic cerebellar injury.] No Shinkei Geka 18:67-70, 1990 (Jpn)