메뉴 건너뛰기




Volumn 57, Issue 5, 2011, Pages 586-589

Obesity stresses cardiac mitochondria even when you are young

Author keywords

aging; cardiomyocyte; mitochondria; oxidative stress

Indexed keywords

ADIPONECTIN; ATRIAL NATRIURETIC FACTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SIRTUIN 1;

EID: 79251474415     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2010.09.039     Document Type: Editorial
Times cited : (17)

References (21)
  • 2
    • 38949135755 scopus 로고    scopus 로고
    • Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome
    • H. Bugger, and E.D. Abel Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome Clin Sci (Lond) 114 2008 195 210
    • (2008) Clin Sci (Lond) , vol.114 , pp. 195-210
    • Bugger, H.1    Abel, E.D.2
  • 3
    • 34347352169 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy revisited
    • S. Boudina, and E.D. Abel Diabetic cardiomyopathy revisited Circulation 115 2007 3213 3223
    • (2007) Circulation , vol.115 , pp. 3213-3223
    • Boudina, S.1    Abel, E.D.2
  • 4
    • 77953440109 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy, causes and effects
    • S. Boudina, and E.D. Abel Diabetic cardiomyopathy, causes and effects Rev Endocr Metab Disord 11 2010 31 39
    • (2010) Rev Endocr Metab Disord , vol.11 , pp. 31-39
    • Boudina, S.1    Abel, E.D.2
  • 5
    • 77956572071 scopus 로고    scopus 로고
    • Mitochondria in the diabetic heart
    • H. Bugger, and E.D. Abel Mitochondria in the diabetic heart Cardiovasc Res 88 2010 229 240
    • (2010) Cardiovasc Res , vol.88 , pp. 229-240
    • Bugger, H.1    Abel, E.D.2
  • 6
    • 70350445742 scopus 로고    scopus 로고
    • Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart
    • E.J. Anderson, A.P. Kypson, E. Rodriguez, C.A. Anderson, E.J. Lehr, and P.D. Neufer Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart J Am Coll Cardiol 54 2009 1891 1898
    • (2009) J Am Coll Cardiol , vol.54 , pp. 1891-1898
    • Anderson, E.J.1    Kypson, A.P.2    Rodriguez, E.3    Anderson, C.A.4    Lehr, E.J.5    Neufer, P.D.6
  • 7
    • 79251478801 scopus 로고    scopus 로고
    • Obesity induces signs of premature cardiac aging in younger patients: The role of mitochondria
    • B. Niemann, Y. Chen, M. Teschner, L. Li, R.-E. Silber, and S. Rohrbach Obesity induces signs of premature cardiac aging in younger patients: the role of mitochondria J Am Coll Cardiol 57 2011 577 585
    • (2011) J Am Coll Cardiol , vol.57 , pp. 577-585
    • Niemann, B.1    Chen, Y.2    Teschner, M.3    Li, L.4    Silber, R.-E.5    Rohrbach, S.6
  • 8
    • 67650094848 scopus 로고    scopus 로고
    • International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes
    • International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes Diabetes Care 32 2009 1327 1334
    • (2009) Diabetes Care , vol.32 , pp. 1327-1334
  • 9
    • 2442492971 scopus 로고    scopus 로고
    • Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women
    • L.R. Peterson, P. Herrero, and K.B. Schechtman Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women Circulation 109 2004 2191 2196
    • (2004) Circulation , vol.109 , pp. 2191-2196
    • Peterson, L.R.1    Herrero, P.2    Schechtman, K.B.3
  • 10
    • 34548385838 scopus 로고    scopus 로고
    • Cardiac steatosis in diabetes mellitus: A 1H-magnetic resonance spectroscopy study
    • J.M. McGavock, I. Lingvay, and I. Zib Cardiac steatosis in diabetes mellitus: a 1H-magnetic resonance spectroscopy study Circulation 116 2007 1170 1175
    • (2007) Circulation , vol.116 , pp. 1170-1175
    • McGavock, J.M.1    Lingvay, I.2    Zib, I.3
  • 11
    • 27444441492 scopus 로고    scopus 로고
    • Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity
    • S. Boudina, S. Sena, B.T. O'Neill, P. Tathireddy, M.E. Young, and E.D. Abel Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity Circulation 112 2005 2686 2695
    • (2005) Circulation , vol.112 , pp. 2686-2695
    • Boudina, S.1    Sena, S.2    O'Neill, B.T.3    Tathireddy, P.4    Young, M.E.5    Abel, E.D.6
  • 12
    • 34548848059 scopus 로고    scopus 로고
    • Mitochondrial energetics in the heart in obesity-related diabetes: Direct evidence for increased uncoupled respiration and activation of uncoupling proteins
    • S. Boudina, S. Sena, and H. Theobald Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins Diabetes 56 2007 2457 2466
    • (2007) Diabetes , vol.56 , pp. 2457-2466
    • Boudina, S.1    Sena, S.2    Theobald, H.3
  • 13
    • 72949110566 scopus 로고    scopus 로고
    • Proteomic remodelling of mitochondrial oxidative pathways in pressure overload-induced heart failure
    • H. Bugger, M. Schwarzer, and D. Chen Proteomic remodelling of mitochondrial oxidative pathways in pressure overload-induced heart failure Cardiovasc Res 85 2010 376 384
    • (2010) Cardiovasc Res , vol.85 , pp. 376-384
    • Bugger, H.1    Schwarzer, M.2    Chen, D.3
  • 14
    • 33947239659 scopus 로고    scopus 로고
    • The failing heartan engine out of fuel
    • S. Neubauer The failing heartan engine out of fuel N Engl J Med 356 2007 1140 1151
    • (2007) N Engl J Med , vol.356 , pp. 1140-1151
    • Neubauer, S.1
  • 15
    • 77957153116 scopus 로고    scopus 로고
    • Metabolic adaptation follows contractile dysfunction in the heart of obese Zucker rats fed a high-fat "western" diet
    • M. Burgmaier, S. Sen, and F. Philip Metabolic adaptation follows contractile dysfunction in the heart of obese Zucker rats fed a high-fat "Western" diet Obesity (Silver Spring) 18 2010 1895 1901
    • (2010) Obesity (Silver Spring) , vol.18 , pp. 1895-1901
    • Burgmaier, M.1    Sen, S.2    Philip, F.3
  • 16
    • 46749125376 scopus 로고    scopus 로고
    • Transcriptional control of mitochondrial biogenesis: The central role of PGC-1alpha
    • R. Ventura-Clapier, A. Garnier, and V. Veksler Transcriptional control of mitochondrial biogenesis: the central role of PGC-1alpha Cardiovasc Res 79 2008 208 217
    • (2008) Cardiovasc Res , vol.79 , pp. 208-217
    • Ventura-Clapier, R.1    Garnier, A.2    Veksler, V.3
  • 17
  • 18
    • 77951872309 scopus 로고    scopus 로고
    • Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1
    • M. Iwabu, T. Yamauchi, and M. Okada-Iwabu Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1 Nature 464 2010 1313 1319
    • (2010) Nature , vol.464 , pp. 1313-1319
    • Iwabu, M.1    Yamauchi, T.2    Okada-Iwabu, M.3
  • 19
    • 63649106676 scopus 로고    scopus 로고
    • Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart
    • S. Boudina, H. Bugger, and S. Sena Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart Circulation 119 2009 1272 1283
    • (2009) Circulation , vol.119 , pp. 1272-1283
    • Boudina, S.1    Bugger, H.2    Sena, S.3
  • 20
    • 73949160605 scopus 로고    scopus 로고
    • Abnormal myocardial insulin signalling in type 2 diabetes and left-ventricular dysfunction
    • S.A. Cook, A. Varela-Carver, and M. Mongillo Abnormal myocardial insulin signalling in type 2 diabetes and left-ventricular dysfunction Eur Heart J 31 2010 100 111
    • (2010) Eur Heart J , vol.31 , pp. 100-111
    • Cook, S.A.1    Varela-Carver, A.2    Mongillo, M.3
  • 21
    • 77951773194 scopus 로고    scopus 로고
    • Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents
    • I. Shimizu, T. Minamino, and H. Toko Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents J Clin Invest 120 2010 1506 1514
    • (2010) J Clin Invest , vol.120 , pp. 1506-1514
    • Shimizu, I.1    Minamino, T.2    Toko, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.