The single pore residue Asp523 in PKD2L1 determines Ca2+ permeation of the PKD1L3/PKD2L1 complex

Biochemical and Biophysical Research Communications

Volumn 404, Issue 4, 2011, Pages 946-951

  Fujimoto, Chisato ^a,b   Ishimaru, Yoshiro ^a   Katano, Yuka ^a   Misaka, Takumi ^a   Yamasoba, Tatsuya ^c   Asakura, Tomiko ^a   Abe, Keiko ^a,d  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOKYO METROPOLITAN NEUROLOGICAL HOSPITAL   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

Calcium permeation; Channel pore; Point mutation; Polycystic kidney disease; Sour taste receptor

Indexed keywords

AMINO ACID; ASPARTIC ACID; CALCIUM ION; CATION CHANNEL; GLUTAMIC ACID; MEMBRANE PROTEIN; POLYCYSTIC KIDNEY DISEASE 1 LIKE 3; POLYCYSTIC KIDNEY DISEASE 2 LIKE 1; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CELL SURFACE; CONTROLLED STUDY; MEMBRANE PERMEABILITY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ASPARTIC ACID; CALCIUM; CALCIUM CHANNELS; CELL LINE; CELL MEMBRANE PERMEABILITY; HUMANS; MICE; MOLECULAR SEQUENCE DATA; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; TRPP CATION CHANNELS;

EID: 79151484522     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.12.086     Document Type: Article

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