Differential effects of statins on endogenous H2S formation in perivascular adipose tissue

Pharmacological Research

Volumn 63, Issue 1, 2011, Pages 68-76

  Wójcicka, Grayna ^a   Jamroz Wiśniewska, Anna ^a   Atanasova, Pepa ^b   Chaldakov, George N ^c   Chylińska Kula, Beata ^a   Bełtowski, Jerzy ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^b MEDICAL UNIVERSITY OF PLOVDIV   (Bulgaria)

^c MEDICAL UNIVERSITY OF VARNA   (Bulgaria)

Author keywords

Coenzyme Q; Hydrogen sulfide; Perivascular adipose tissue; Potassium channels; Statins

Indexed keywords

ATORIS; ATORVASTATIN; COENZYME Q 9; HYDROGEN SULFIDE; OXIDOREDUCTASE; PHENYLEPHRINE; PRAVASTATIN; SULFIDE:QUINONE OXIDOREDUCTASE; UBIQUINONE; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; AORTA MEDIA; ARTICLE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; LIVER LEVEL; LIVER METABOLISM; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; PERIVASCULAR ADIPOSE TISSUE; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTILITY; SYNTHESIS; TISSUE DISTRIBUTION; TREATMENT DURATION; VASCULAR RING;

ADIPOSE TISSUE; ANIMALS; AORTA, THORACIC; CHOLESTEROL; CHOLESTEROL, HDL; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPTANOIC ACIDS; HYDROGEN SULFIDE; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; KATP CHANNELS; LIVER; MALE; MITOCHONDRIA, LIVER; OXIDATION-REDUCTION; POTASSIUM CHANNEL BLOCKERS; PRAVASTATIN; PYRROLES; QUINONE REDUCTASES; RATS; RATS, WISTAR; SULFIDES; TRIGLYCERIDES; UBIQUINONE; VASOCONSTRICTOR AGENTS; VASODILATION;

EID: 79151473051     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2010.10.011     Document Type: Article

References (45)

1. 2S) Cell Biochem Funct 28 2010 95 106
2. M.M. Gadalla, and S.H. Snyder Hydrogen sulfide as a gasotransmitter J Neurochem 113 2010 14 26
3. M. Bhatia Hydrogen sulfide and substance P in inflammation Antioxid Redox Signal 12 2010 1191 1202
4. T.M. Hildebrandt, and M.K. Grieshaber Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria FEBS J 275 2008 3352 3361
5. W. Qiao, T. Chaoshu, J. Hongfang, and D. Junbao Endogenous hydrogen sulfide is involved in the pathogenesis of atherosclerosis Biochem Biophys Res Commun 396 2010 182 186
6. J. Bełtowski, A. Jamroz-Wiśniewska, and D. Tokarzewska Hydrogen sulfide and its modulation in arterial hypertension and atherosclerosis Cardiovasc Hematol Agents Med Chem 8 2010 173 186
7. C.K. Nicholson, and J.W. Calvert Hydrogen sulfide and ischemia-reperfusion injury Pharmacol Res 62 2010 289 297
8. 2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase Science 322 2008 587 590
9. ATP channel opener EMBO J 20 2001 6008 6016
10. L. Fang, J. Zhao, Y. Chen, T. Ma, G. Xu, and C. Tang Hydrogen sulfide derived from periadventitial adipose tissue is a vasodilator J Hypertens 27 2009 2174 2185
11. N. Shibuya, Y. Mikami, Y. Kimura, N. Nagahara, and H. Kimura Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide J Biochem 146 2009 623 626
12. L. Li, M. Whiteman, Y.Y. Guan, K.L. Neo, Y. Cheng, and S.W. Lee Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide Circulation 117 2008 2351 2360
13. Y. Shitara, and Y. Sugiyama Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions Pharmacol Ther 112 2006 71 105
14. M.H. Stipanuk, and P.W. Beck Characterization of the enzymic capacity for cysteine desulfhydration in liver and kidney of the rat Biochem J 206 1982 267 277
15. M. Xia, L. Chen, R.W. Muh, P.L. Li, and N. Li Production and actions of hydrogen sulfide, a novel gaseous bioactive substance, in the kidneys J Pharmacol Exp Ther 329 2009 1056 1062
16. O.H. Lowry, N.I. Rosenbrough, A.L. Farr, and R.J. Randall Protein measurement with the Folin phenol reagent J Biol Chem 193 1951 265 275
17. M.H. Stipanuk Effect of excess dietary methionine on the catabolism of cysteine in rats J Nutr 109 1979 2126 2139
18. Q. Wang, H.R. Liu, Q. Mu, P. Rose, and Y.Z. Zhu S-propargyl-cysteine protects both adult rat hearts and neonatal cardiomyocytes from ischemia/hypoxia injury: the contribution of the hydrogen sulfide-mediated pathway J Cardiovasc Pharmacol 54 2009 139 146
19. U. Theissen, and W. Martin Sulfide:quinone oxidoreductase (SQR) from the lugworm Arenicola marina shows cyanide- and thioredoxin-dependent activity FEBS J 275 2008 1131 1139
20. H. Yamazaki, M. Suzuki, T. Aoki, S. Morikawa, T. Maejima, and F. Sato Influence of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on ubiquinone levels in rat skeletal muscle and heart: relationship to cytotoxicity and inhibitory activity for cholesterol synthesis in human skeletal muscle cells J Atheroscler Thromb 13 2006 295 307
21. B.R. Krause, and R.S. Newton Lipid-lowering activity of atorvastatin and lovastatin in rodent species: triglyceride-lowering in rats correlates with efficacy in LDL animal models Atherosclerosis 117 1995 237 244
22. Q. Zhou, and J.K. Liao Statins and cardiovascular diseases: from cholesterol lowering to pleiotropy Curr Pharm Des 15 2009 467 478
23. G. Heeba, M.E. Moselhy, M. Hassan, M. Khalifa, R. Gryglewski, and T. Maliński Anti-atherogenic effect of statins: role of nitric oxide, peroxynitrite and haem oxygenase-1 Br J Pharmacol 156 2009 1256 1266
24. J. Li, J.J. Li, J.G. He, J.L. Nan, Y.L. Guo, and C.M. Xiong Atorvastatin decreases C-reactive protein-induced inflammatory response in pulmonary artery smooth muscle cells by inhibiting nuclear factor-kappaB pathway Cardiovasc Ther 28 2010 8 14
25. M. Bentinger, M. Tekle, and G. Dallner Coenzyme Q - biosynthesis and functions Biochem Biophys Res Commun 396 2010 74 79
26. R.A. Willis, K. Folkers, J.L. Tucker, C.Q. Ye, L.J. Xia, and H. Tamagawa Lovastatin decreases coenzyme Q levels in rats Proc Natl Acad Sci USA 87 1990 8928 8930 (Pubitemid 120007622)
27. K. Folkers, P. Langsjoen, R. Willis, P. Richardson, L.J. Xia, and C.Q. Ye Lovastatin decreases coenzyme Q levels in humans Proc Natl Acad Sci USA 87 1990 8931 8934 (Pubitemid 120007623)
28. P. Löw, M. Andersson, C. Edlund, and G. Dallner Effects of mevinolin treatment on tissue dolichol and ubiquinone levels in the rat Biochim Biophys Acta 1165 1992 102 109
29. L. Marcoff, and P.D. Thompson The role of coenzyme Q10 in statin-associated myopathy: a systematic review J Am Coll Cardiol 49 2007 2231 2237
30. G.P. Littarru, and P. Langsjoen Coenzyme Q10 and statins: biochemical and clinical implications Mitochondrion 7 Suppl. 2007 S168 S174
31. M. Goubern, M. Andriamihaja, T. Nübel, F. Blachier, and F. Bouillaud Sulfide, the first inorganic substrate for human cells FASEB J 21 2007 1699 1706
32. C.E. Cooper, and G.C. Brown The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance J Bioenerg Biomembr 40 2008 533 539
33. M. Zhang, S. Wakitani, K. Hayashi, R. Miki, and M. Kawamukai High production of sulfide in coenzyme Q deficient fission yeast Biofactors 32 2008 91 98
34. X. Feng, Y. Chen, J. Zhao, C. Tang, Z. Jiang, and B. Geng Hydrogen sulfide from adipose tissue is a novel insulin resistance regulator Biochem Biophys Res Commun 380 2009 153 159
35. C.I. Coleman, K. Reinhart, J. Kluger, and C.M. White The effect of statins on the development of new-onset type 2 diabetes: a meta-analysis of randomized controlled trials Curr Med Res Opin 24 2008 1359 1362
36. M.E. Murphy, and J.E. Brayden Nitric oxide hyperpolarizes rabbit mesenteric arteries via ATP-sensitive potassium channels J Physiol 486 1995 47 58
37. C. Ribiere, A.M. Jaubert, N. Gaudiot, D. Sabourault, M.L. Marcus, and J.L. Boucher White adipose tissue nitric oxide synthase: a potential source for NO production Biochem Biophys Res Commun 222 1996 706 712
38. A.Y. Kolyada, A. Fedtsov, and N.E. Madias 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors upregulate inducible NO synthase expression and activity in vascular smooth muscle cells Hypertension 38 2001 1024 1029
39. Y. Hattori, N. Nakanishi, and K. Kasai Statin enhances cytokine-mediated induction of nitric oxide synthesis in vascular smooth muscle cells Cardiovasc Res 54 2002 649 658
40. B.A. Schick, R. Laaksonen, J.J. Frohlich, H. Päivä, T. Lehtimäki, and K.H. Humphries Decreased skeletal muscle mitochondrial DNA in patients treated with high-dose simvastatin Clin Pharmacol Ther 81 2007 650 653
41. K. Nakahara, M. Kuriyama, Y. Sonoda, H. Yoshidome, H. Nakagawa, and J. Fujiyama Myopathy induced by HMG-CoA reductase inhibitors in rabbits: a pathological, electrophysiological, and biochemical study Toxicol Appl Pharmacol 152 1998 99 106
42. W.H. Schaefer, J.W. Lawrence, A.F. Loughlin, D.A. Stoffregen, L.A. Mixson, and D.C. Dean Evaluation of ubiquinone concentration and mitochondrial function relative to cerivastatin-induced skeletal myopathy in rats Toxicol Appl Pharmacol 194 2004 10 23
43. S. Tavintharan, C.N. Ong, K. Jeyaseelan, M. Sivakumar, S.C. Lim, and C.F. Sum Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: a possible role in statin-induced hepatotoxicity? Toxicol Appl Pharmacol 223 2007 173 179
44. A.J. Duncan, I.P. Hargreaves, M.S. Damian, J.M. Land, and S.J. Heales Decreased ubiquinone availability and impaired mitochondrial cytochrome oxidase activity associated with statin treatment Toxicol Mech Methods 19 2009 44 50
45. K.R. Olson Hydrogen sulfide and oxygen sensing: implications in cardiorespiratory control J Exp Biol 211 2008 2727 2734