Functional analysis of three recombinant A1-VWF domain mutants in comparison to wild type and plasma-derived VWF facilitates subtyping in type 2 von Willebrand disease

Thrombosis Research

Volumn 127, Issue 2, 2011, Pages 161-166

  Chegeni, Rouzbeh ^a   Vickars, Linda ^b   Favaloro, Emmanuel J ^c   Lillicrap, David ^a   Othman, Maha ^a,d  

^a QUEEN S UNIVERSITY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c Western Sydney Area Health Service   (Australia)

^d LAURENTIAN UNIVERSITY   (Canada)

Author keywords

A1 Domain mutations; Platelet VWF binding; RIPA; Type 2 VWD

Indexed keywords

COLLAGEN; RECOMBINANT VON WILLEBRAND FACTOR; RISTOCETIN; VON WILLEBRAND FACTOR;

AMINO ACID SUBSTITUTION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; DNA SEQUENCE; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; MOLECULAR DIAGNOSIS; MUTATIONAL ANALYSIS; PHENOTYPIC VARIATION; PRIORITY JOURNAL; THROMBOCYTE; VON WILLEBRAND DISEASE; WILD TYPE;

BLOOD PLATELETS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHENOTYPE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TRANSFECTION; VON WILLEBRAND DISEASE, TYPE 2; VON WILLEBRAND FACTOR;

EID: 79151471425     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2010.11.006     Document Type: Article

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