Fe(III)-salen and salphen complexes induce caspase activation and apoptosis in human cells

Journal of Biomolecular Screening

Volumn 16, Issue 1, 2011, Pages 26-35

  Ansari, Khairul I ^a   Kasiri, Sahba ^a   Grant, James D ^a   Mandal, Subhrangsu S ^a  

^a UNIVERSITY OF TEXAS AT ARLINGTON   (United States)

Author keywords

anti tumor drugs; apoptosis; caspase activation; cytochrome c; cytotoxicity; Metallo salen

Indexed keywords

3, 3' DIHYDROXYSALEN FE (III) CHLORIDE; 3, 3' DIHYDROXYSALPHEN FE (III) CHLORIDE; 3, 3' DIMETHOXYSALEN FE (III) CHLORIDE; 3, 3' DIMETHOXYSALPHEN FE (III) CHLORIDE; 4, 4' DIHYDROXYSALEN FE (III) CHLORIDE; 4, 4' DIHYDROXYSALPHEN FE (III) CHLORIDE; 4, 4' DIMETHOXYSALEN FE (III) CHLORIDE; 4, 4' DIMETHOXYSALPHEN FE (III) CHLORIDE; 5, 5' DIHYDROXYSALEN FE (III) CHLORIDE; 5, 5' DIHYDROXYSALPHEN FE (III) CHLORIDE; 5, 5' DIMETHOXYSALEN FE (III) CHLORIDE; 5, 5' DIMETHOXYSALPHEN FE (III) CHLORIDE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; CISPLATIN; CYTOCHROME C; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL VIABILITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL;

APOPTOSIS; CASPASE 3; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; ETHYLENEDIAMINES; FERRIC COMPOUNDS; HUMANS; INHIBITORY CONCENTRATION 50; MITOCHONDRIA; PHENYLENEDIAMINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78951484863     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057110385227     Document Type: Article

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