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Volumn 61, Issue 7, 1996, Pages 2326-2331

Synthesis of a functionalized salen-copper complex and its interaction with DNA

Author keywords

[No Author keywords available]

Indexed keywords

COPPER COMPLEX; SALICYLIC ACID DERIVATIVE;

EID: 0029926195     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo951840c     Document Type: Article
Times cited : (126)

References (34)
  • 1
    • 0022456486 scopus 로고
    • (a) Barton, J. K. Science 1986, 233, 727-734.
    • (1986) Science , vol.233 , pp. 727-734
    • Barton, J.K.1
  • 13
    • 15844368952 scopus 로고    scopus 로고
    • note
    • Footprinting experiments using DNAase I as cleaving agent have failed to confirm the apparent preference for binding to AT sequences inferred from the CD titration experiments. The lack of detectable footprints may be due to the low affinity of the salen·Cu complex for DNA and possibly from the mechanism of recognition of DNA by DNAase I. The nuclease binds to the minor groove of DNA whereas compound 1 is suspected to interact within the major groove.
  • 28
    • 15844376210 scopus 로고    scopus 로고
    • note
    • - radicals capable of reacting with the deoxyribose residues in DNA.
  • 33
    • 0001702435 scopus 로고
    • Krause, S., Ed.; Plenum Publishing Corp.: New York
    • (a) Houssier, C. In Molecular Electro-Optics; Krause, S., Ed.; Plenum Publishing Corp.: New York, 1981; pp 363-398.
    • (1981) Molecular Electro-Optics , pp. 363-398
    • Houssier, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.