Minority HIV mutation detection in dried blood spots indicates high specimen integrity and reveals hidden archived drug resistance

Journal of Clinical Virology

Volumn 50, Issue 2, 2011, Pages 148-152

  Wei, Xierong ^a   Youngpairoj, Ae S ^a   Garrido, Carolina ^b   Zahonero, Natalia ^b   Corral, Angelica ^b   de Mendoza, Carmen ^b   Heneine, Walid ^a   Johnson, Jeffrey A ^a   Garcia Lerma, J Gerardo ^a  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

Author keywords

Antiretroviral therapy; Archived drug resistance; Cost effective specimen; Dried blood spots; Minority resistance mutations; Real time PCR

Indexed keywords

ABACAVIR PLUS LAMIVUDINE PLUS ZIDOVUDINE; LAMIVUDINE; NEVIRAPINE; NUCLEIC ACID; TENOFOVIR; ZIDOVUDINE;

ANTIVIRAL RESISTANCE; ANTIVIRAL SUSCEPTIBILITY; ARTICLE; BLOOD EXAMINATION; CLINICAL ARTICLE; DRIED BLOOD SPOTS; GENE AMPLIFICATION; GENE MUTATION; GENOTYPE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT OUTCOME; VIRUS LOAD;

ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; BLOOD; BLOOD SPECIMEN COLLECTION; DNA, VIRAL; DRUG RESISTANCE, VIRAL; GENOTYPE; HIV INFECTIONS; HIV-1; HUMANS; MUTATION; NUCLEIC ACID AMPLIFICATION TECHNIQUES; POLYMERASE CHAIN REACTION;

EID: 78951479088     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcv.2010.11.006     Document Type: Article

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