Altered sialylation on the cell-surface proteins of dexamethasone-treated human macrophages contributes to augmented uptake of apoptotic neutrophils

Immunology Letters

Volumn 135, Issue 1-2, 2011, Pages 88-95

  Mádi, András ^a   Majai, Gyöngyike ^a   Koy, Cornelia ^b   Vámosi, György ^a   Szántó, Attila ^a   Glocker, Michael O ^b   Fésüs, László ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Annexin II; Apoptosis; Dexamethasone; Haptoglobin; Human macrophages; Programmed cell death

Indexed keywords

BETA HAPTOGLOBIN; CELL SURFACE PROTEIN; DEXAMETHASONE; HAPTOGLOBIN; HLA ANTIGEN CLASS 2; LECTIN; LIPOCORTIN 2; SIALIC ACID; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CELL SURFACE; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; MACROPHAGE FUNCTION; PHAGOCYTOSIS; PRIORITY JOURNAL; SIALYLATION;

ANTI-INFLAMMATORY AGENTS; APOPTOSIS; DEXAMETHASONE; HUMANS; MACROPHAGES; MEMBRANE PROTEINS; N-ACETYLNEURAMINIC ACID; NEUTROPHILS; PLANT LECTINS; RIBOSOME INACTIVATING PROTEINS;

EID: 78751702673     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2010.10.002     Document Type: Article

References (42)

1. Savill J., Dransfield I., Gregory C., Haslett C. A blast from the past: clearance of apoptotic cells regulates immune responses. Nat Rev Immunol 2002, 2:965-975.
2. Haslett C., Savill J.S., Whyte M.K., Stern M., Dransfield I., Meagher L.C. Granulocyte apoptosis and the control of inflammation. Philos Trans R Soc Lond B Biol Sci 1994, 345:327-333.
3. Goulding N.J., Guyre P.M. Glucocorticoids, lipocortins and the immune response. Curr Opin Immunol 1993, 5:108-113.
4. Schleimer R.P. An overview of glucocorticoid anti-inflammatory actions. Eur J Clin Pharmacol 1993, 45:S3-S7. discussion S43-4.
5. Giles K.M., Ross K., Rossi A.G., Hotchin N.A., Haslett C., Dransfield I. Glucocorticoid augmentation of macrophage capacity for phagocytosis of apoptotic cells is associated with reduced p130Cas expression, loss of paxillin/pyk2 phosphorylation, and high levels of active Rac. J Immunol 2001, 167:976-986.
6. Heasman S.J., Giles K.M., Rossi A.G., Allen J.E., Haslett C., Dransfield I. Interferon gamma suppresses glucocorticoid augmentation of macrophage clearance of apoptotic cells. Eur J Immunol 2004, 34:1752-1761.
7. McColl A., Bournazos S., Franz S., Perretti M., Morgan P., Haslett C., et al. Glucocorticoids induce protein S-dependent phagocytosis of apoptotic neutrophils by human macrophages. J Immunol 2009, 183:2167-2175.
8. Savill J., Dransfield I., Gregory C., Haslett C.A. A blast from the past: clearance of apoptotic cells regulates immune responses. Nat Rev Immunol 2002, 2:965-975.
9. Majai G., Petrovski G., Fesus L. Inflammation and the apopto-phagocytic system. Immunol Lett 2006, 104:94-101.
10. Ehrchen J., Steinmuller L., Barczyk K., Tenbrock K., Nacken W., Eisenacher M., et al. Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype. Blood 2007, 109:1265-1274.
11. Wyllie A.H., Kerr J.F., Currie A.R. Cell death: the significance of apoptosis. Int Rev Cytol 1980, 68:251-306.
12. Majai G., Sarang Z., Csomos K., Zahuczky G., Fesus L. PPARgamma-dependent regulation of human macrophages in phagocytosis of apoptotic cells. Eur J Immunol 2007, 37:1343-1354.
13. Rahbar A.M., Fenselau C. Integration of Jacobson's pellicle method into proteomic strategies fro plasmam membrane proteins. J Proteome Res 2004, 3:1267-1277.
14. Roth J., Zuber C., Sata T., Li W.P. Lectin-gold histochemistry on paraffin and lowicryl K4M sections using biotin and digoxigenin-conjugated lectins. Lectin methods and protocols 1998, 41-54. Humana Press, Totowa, NJ. J.M. Rhodes, J.D. Milton (Eds.).
15. Bene L., Kanyari Z., Bodnar A., Kappelmayer J., Waldmann T.A., Vamosi G., et al. Colorectal carcinoma rearranges cell surface protein topology and density in CD4(+) T cells. Biochem Biophys Res Commun 2007, 361:202-207.
16. Madi A., Mikkat S., Ringel B., Thiesen H.J., Glocker M.O. Profiling stage-dependent changes of protein expression in Caenorhabditis elegans by mass spectrometric proteome analysis leads to the identification of stage-specific marker proteins. Electrophoresis 2003, 24:1809-1817.
17. Neuhoff V., Arold N., Taube D., Ehrhardt W. Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G-250 and R-250. Electrophoresis 1988, 9:255-262.
18. Shevchenko A., Wilm M., Vorm O., Mann M. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 1996, 68:850-858.
19. Sinz A., Bantscheff M., Mikkat S., Ringel B., Drynda S., Kekow J., et al. Mass spectrometric proteome analyses of synovial fluids and plasmas from patients suffering from rheumatoid arthritis and comparison to reactive arthritis or osteoarthritis. Electrophoresis 2002, 23:3445-3456.
20. Koy C., Mikkat S., Raptakis E., Sutton C., Resch M., Tanaka K., et al. Matrix-assisted laser desorption/ionization-quadrupole ion trap-time of flight mass spectrometry sequencing resolves structures of unidentified peptides obtained by in-gel tryptic digestion of haptoglobin derivatives from human plasma proteomes. Proteomics 2003, 3:851-858.
21. Shibuya N., Goldstein I.J., Broekaert W.F., Nsimba-Lubaki M., Peeters B., Peumans W.J. The elderberry (Sambucus nigra L.) bark lectin recognizes the Neu5Ac(alpha 2-6)Gal/GalNAc sequence. J Biol Chem 1987, 262:1596-1601.
22. Hanasaki K., Powell L.D., Varki A. Binding of human plasma sialoglycoproteins by the B cell-specific lectin CD22. Selective recognition of immunoglobulin M and haptoglobin. J Biol Chem 1995, 270:7543-7550.
23. Wagner L., Gessl A., Parzer S.B., Base W., Waldhausl W., Pasternack M.S. Haptoglobin phenotyping by newly developed monoclonal antibodies. Demonstration of haptoglobin uptake into peripheral blood neutrophils and monocytes. J Immunol 1996, 156:1989-1996.
24. Kim I.S., Lee I.H., Lee J.H., Lee S.Y. Induction of haptoglobin by all-trans retinoic acid in THP-1 human monocytic cell line. Biochem Biophys Res Commun 2001, 284:738-742.
25. Kijimoto-Ochiai S., Hatae T., Katagiri Y.U., Okuyama H. Microheterogeneity and oligosaccharide chains on the beta chains of HLA-DR, human major histocompatibility complex class II antigen, analyzed by the lectin-nitrocellulose sheet method. J Biochem 1989, 106:771-777.
26. McColl A., Michlewska S., Dransfield I., Rossi A.G. Effects of glucocorticoids on apoptosis and clearance of apoptotic cells. Sci World J 2007, 7:1165-1181.
27. Bar-Shavit Z., Kahn A.J., Pegg L.E., Stone K.R., Teitelbaum S.L. Glucocorticoids modulate macrophage surface oligosaccharides and their bone binding activity. J Clin Invest 1984, 73:1277-1283.
28. Edge A.S., Karasik A., Yamada K., Kahn C.R. Effect of dexamethasone on the carbohydrate chains of the insulin receptor. Biochem Biophys Res Commun 1994, 200:852-859.
29. van Dijk W., Boers W., Sala M., Lasthuis A.M., Mookerjea S. Activity and secretion of sialyltransferase in primary monolayer cultures of rat hepatocytes cultured with and without dexamethasone. Biochem Cell Biol 1986, 64:79-84.
30. Wang X.C., O'Hanlon T.P., Lau J.T. Regulation of beta-galactoside alpha 2,6-sialyltransferase gene expression by dexamethasone. J Biol Chem 1989, 264:1854-1859.
31. Vandamme V., Pierce A., Verbert A., Delannoy P. Transcriptional induction of beta-galactoside alpha-2,6-sialyltransferase in rat fibroblast by dexamethasone. Eur J Biochem 1993, 211:135-140.
32. Hamr A., Vlasakova V., Kolinska J. Alpha 2,6-sialyltransferase predominates in cultured jejunum of suckling rats: it is up-regulated by dexamethasone and secreted during cultivation. Biochim Biophys Acta 1993, 1157:285-289.
33. Cohen A.M., Singer R., Sagiv M., Kyzer S., Segenreich E., Levinsky H. Cyclophosphamide, doxorubicin, dexamethasone and procarbazine: effect on seminal plasma sialyltransferase activity. Adv Contracept Deliv Syst 1992, 8:233-237.
34. Goulet F., Moore K.G., Sartorelli A.C. Glycosylation of annexin I and annexin II. Biochem Biophys Res Commun 1992, 188:554-558.
35. Fan X., Krahling S., Smith D., Williamson P., Schlegel R.A. Macrophage surface expression of annexins I and II in the phagocytosis of apoptotic lymphocytes. Mol Biol Cell 2004, 15:2863-2872.
36. Fadok V.A., Voelker D.R., Campbell P.A., Cohen J.J., Bratton D.L., Henson P.M. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol 1992, 148:2207-2216.
37. Callahan M.K., Williamson P., Schlegel R.A. Surface expression of phosphatidylserine on macrophages is required for phagocytosis of apoptotic thymocytes. Cell Death Differ 2000, 7:645-653.
38. Maderna P., Yona S., Perretti M., Godson C. Modulation of phagocytosis of apoptotic neutrophils by supernatant from dexamethasone-treated macrophages and annexin-derived peptide Ac2-26. J Immunol 2005, 174:3727-3733.
39. Kelm S., Schauer R. Sialic acids in molecular and cellular interactions. Int Rev Cytol 1997, 175:137-240.
40. Varki A. Glycan-based interactions involving vertebrate sialic-acid-recognizing proteins. Nature 2007, 446:1023-1029.
41. Buttgereit F., Da Silva J.A.P., Boers M., Burmester G.R., Cutolo M., Jacobs J., et al. Standardised nomenclature for glucocorticoid dosages and glucocorticoid treatment regimens: current questions and tentative answers in rheumatology. Ann Rheum Dis 2002, 61:718-722.
42. van der Goes A., Hoekstra K., van den Berg T.K., Dijkstra C.D. Dexamethasone promotes phagocytosis and bacterial killing by human monocytes/macrophages in vitro. J Leukoc Biol 2000, 67:801-807.