Retention and selectivity effects caused by bonding of a polar urea-type ligand to silica: A study on mixed-mode retention mechanisms and the pivotal role of solute-silanol interactions in the hydrophilic interaction chromatography elution mode

Journal of Chromatography A

Volumn 1218, Issue 7, 2011, Pages 882-895

  Bicker, Wolfgang ^a,b   Wu, JunYan ^a   Yeman, Helen ^c   Albert, Klaus ^c   Lindner, Wolfgang ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b FTC Forensic Toxicological Laboratory Ltd   (Austria)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Hydrophilic interaction chromatography; Ligand surface density; Mixed mode chromatography; Retention mechanisms; Selectivity; Silanol interactions

Indexed keywords

HYDROPHILIC INTERACTION CHROMATOGRAPHY; MIXED-MODE CHROMATOGRAPHY; RETENTION MECHANISM; SELECTIVITY; SILANOLS;

ADSORPTION; AMIDES; AMINES; AMINO ACIDS; CLUSTER ANALYSIS; HIERARCHICAL SYSTEMS; HYDROGEN BONDS; HYDROPHILICITY; LIGANDS; METABOLISM; PH EFFECTS; SILICA; SURFACES; UREA;

CHROMATOGRAPHY;

4 HYDROXYBENZOIC ACID; GALLIC ACID; GUANINE; GUANOSINE; SILANOL; TYRAMINE; TYROSINE;

ADSORPTION; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL BINDING; CHEMICAL INTERACTION; CHEMICAL STRUCTURE; CROSS LINKING; DENSITY; ELUTION; ENTHALPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN BOND; HYDROPHILIC INTERACTION CHROMATOGRAPHY; HYDROPHILICITY; PH; PRIORITY JOURNAL; SOLUTE; TEMPERATURE;

ACETONITRILES; CHROMATOGRAPHY, AFFINITY; CLUSTER ANALYSIS; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIGANDS; MODELS, CHEMICAL; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; ORGANOSILICON COMPOUNDS; SALTS; SURFACE PROPERTIES; TEMPERATURE; UREA;

EID: 78751702266     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2010.10.073     Document Type: Article

References (41)

1. Lämmerhofer M. J. Sep. Sci. 2008, 31:1419.
2. Lämmerhofer M. J. Sep. Sci. 2010, 33:679.
3. Hemström P., Irgum K. J. Sep. Sci. 2006, 29:1784.
4. Ikegami T., Tomomatsu K., Takubo H., Horie K., Tanaka N. J. Chromatogr. A 2008, 1184:474.
5. Iwasaki Y., Ishii Y., Ito R., Saito K., Nakazawa H. J. Liq. Chromatogr. Relat. Technol. 2007, 30:2117.
6. Yoshida T. J. Biochem. Biophys. Meth. 2004, 60:265.
7. Bicker W., Wu J., Lämmerhofer M., Lindner W. J. Sep. Sci. 2008, 31:2971.
8. Quiming N.S., Denola N.L., Soliev A.B., Saito Y., Jinno K. Anal. Bioanal. Chem. 2007, 389:1477.
9. Grumbach E.S., Diehl D.M., Neue U.D. J. Sep. Sci. 2008, 31:1511.
10. Jandera P. J. Sep. Sci. 2008, 31:1421.
11. Zhou T., Lucy C.A. J. Chromatogr. A 2010, 1217:82.
12. Zhou T., Lucy C.A. J. Chromatogr. A 2008, 1187:87.
13. Randon J., Huguet S., Demesmay C., Berthod A. J. Chromatogr. A 2010, 1217:1496.
14. McCalley D.V., Neue U.D. J. Chromatogr. A 2008, 1192:225.
15. Apfelthaler E., Bicker W., Lämmerhofer M., Sulyok M., Krska R., Lindner W., Schuhmacher R. J. Chromatogr. A 2008, 1191:171.
16. Bicker W., Lämmerhofer M., Keller T., Schuhmacher R., Krska R., Lindner W. Anal. Chem. 2006, 78:5884.
17. Lämmerhofer M., Richter M., Wu J., Nogueira R., Bicker W., Lindner W. J. Sep. Sci. 2008, 31:2572.
18. Mant C.T., Hodges R.S. J. Sep. Sci. 2008, 31:2754.
19. Alpert A.J. Anal. Chem. 2008, 80:62.
20. Chen Y., Bicker W., Wu J., Xie M.Y., Lindner W. J. Chromatogr. A 2010, 1217:1255.
21. Chirita R.I., West C., Finaru A.L., Elfakir C. J. Chromatogr. A 2010, 1217:3091.
22. Van Dorpe S., Vergote V., Pezeshki A., Burvenich C., Peremans K., De Spiegeleer B. J. Sep. Sci. 2010, 33:728.
23. Valette J.C., Demesmay C., Rocca J.L., Verdon E. Chromatographia 2004, 59:55.
24. Quiming N.S., Denola N.L., Saito Y., Catabay A.P., Jinno K. Chromatographia 2008, 67:507.
25. Wu J.Y., Bicker W., Lindner W. J. Sep. Sci. 2008, 31:1492.
26. Karatapanis A.E., Fiamegos Y.C., Stalikas C.D. Chromatographia 2010, 71:751.
27. Wang Y., Yang J., Lu X., Xu G.W. Chin. Chem. Lett. 2007, 18:565.
28. McCalley D.V. J. Chromatogr. A 2010, 1217:3408.
29. Guo Y., Gaiki S. J. Chromatogr. A 2005, 1074:71.
30. Guo Y., Srinivasan S., Gaiki S. Chromatographia 2007, 66:223.
31. Neue U.D., Hudalla C.J., Iraneta P.C. J. Sep. Sci. 2010, 33:838.
32. Hao Z., Xiao B., Weng N. J. Sep. Sci. 2008, 31:1449.
33. Quiming N.S., Denola N.L., Bin Samsuri S.R.B., Saito Y., Jinno K. J. Sep. Sci. 2008, 31:1537.
34. Quiming N.S., Denola N.L., Saito Y., Jinno K. Anal. Bioanal. Chem. 2007, 388:1693.
35. Quiming N.S., Denola N.L., Saito Y., Jinno K. J. Sep. Sci. 2008, 31:1550.
36. Quiming N.S., Denola N.L., Soliev A.B., Saito Y., Jinno K. Anal. Sci. 2008, 24:139.
37. Quiming N.S., Denola N.L., Ueta I., Saito Y., Tatematsu S., Jinno K. Anal. Chim. Acta 2007, 598:41.
38. Nguyen H.P., Yang S.H., Wigginton J.G., Simpkins J.W., Schug K.A. J. Sep. Sci. 2010, 33:793.
39. McCalley D.V. J. Chromatogr. A 2007, 1171:46.
40. Chester T.L., Coym J.W. J. Chromatogr. A 2003, 1003:101.
41. Neue U.D., Tran K., Mendez A., Carr P.W. J. Chromatogr. A 2005, 1063:35.