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Volumn 879, Issue 3-4, 2011, Pages 236-242
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Budesonide quantification by HPLC coupled to atmospheric pressure photoionization (APPI) tandem mass spectrometry. Application to a comparative systemic bioavailability of two budesonide formulations in healthy volunteers
a,b
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Author keywords
Allergy; Bioavailability; Budesonide; LC MS MS; Nasal spray; Pharmacokinetics
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Indexed keywords
ACCURACY AND PRECISION;
ANALYTES;
ANALYTICAL COLUMNS;
ANALYTICAL METHOD;
ATMOSPHERIC PRESSURE PHOTO IONIZATION;
AUTOSAMPLERS;
BIOAVAILABILITY;
BUDESONIDE;
CROSSOVER DESIGN;
FOOD AND DRUG ADMINISTRATION;
HUMAN PLASMAS;
INTERNAL STANDARDS;
LC-MS/MS;
LINEAR CALIBRATION CURVE;
LIQUID-LIQUID EXTRACTION;
NASAL SPRAY;
PLASMA SAMPLES;
RELATIVE BIOAVAILABILITY;
ROBUST METHODS;
RUNTIMES;
TANDEM MASS SPECTROMETRY;
ALLERGIES;
ATMOSPHERIC PRESSURE;
BIOCHEMISTRY;
COLUMN CHROMATOGRAPHY;
ETHERS;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HIGH PRESSURE LIQUID CHROMATOGRAPHY;
LIQUIDS;
MASS SPECTROMETRY;
PHARMACOKINETICS;
PHOTOIONIZATION;
PLASMA (HUMAN);
SOLVENT EXTRACTION;
DRUG PRODUCTS;
BUDECORT AQUA;
BUDESONIDE;
NOSE SPRAY;
UNCLASSIFIED DRUG;
ACCURACY;
ADULT;
AREA UNDER THE CURVE;
ARTICLE;
ATMOSPHERIC PRESSURE PHOTOIONIZATION TANDEM MASS SPECTROMETRY;
COMPARATIVE STUDY;
DRUG ABSORPTION;
DRUG BIOAVAILABILITY;
DRUG BLOOD LEVEL;
DRUG FORMULATION;
FEMALE;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
HUMAN EXPERIMENT;
LIQUID LIQUID EXTRACTION;
MALE;
PRIORITY JOURNAL;
QUANTITATIVE ANALYSIS;
RANDOMIZED CONTROLLED TRIAL;
SENSITIVITY ANALYSIS;
SINGLE DRUG DOSE;
TANDEM MASS SPECTROMETRY;
ADOLESCENT;
ADULT;
BIOLOGICAL AVAILABILITY;
BRONCHODILATOR AGENTS;
BUDESONIDE;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CROSS-OVER STUDIES;
DESOGESTREL;
DRUG STABILITY;
FEMALE;
HUMANS;
LEAST-SQUARES ANALYSIS;
MALE;
MIDDLE AGED;
NASAL SPRAYS;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
TANDEM MASS SPECTROMETRY;
THERAPEUTIC EQUIVALENCY;
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EID: 78751700994
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2010.12.003 Document Type: Article |
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Times cited : (17)
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References (22)
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