메뉴 건너뛰기




Volumn 8, Issue 1, 2011, Pages 85-95

Regenerating matrix-based therapy for chronic wound healing: A prospective within-subject pilot study

Author keywords

Glycosaminoglycans; Heparan sulphate; Wound healing; Wound pain

Indexed keywords

CACIPLIQ20; GLUCOSE POLYMER; UNCLASSIFIED DRUG;

EID: 78751688180     PISSN: 17424801     EISSN: 1742481X     Source Type: Journal    
DOI: 10.1111/j.1742-481X.2010.00748.x     Document Type: Article
Times cited : (35)

References (72)
  • 1
    • 45949099627 scopus 로고    scopus 로고
    • Quality of life in healing diabetic wounds: does the end justify the means?
    • Armstrong DG, Lavery LA, Wrobel JS, Vileikyte L. Quality of life in healing diabetic wounds: does the end justify the means? J Foot Ankle Surg 2008;47:278-82.
    • (2008) J Foot Ankle Surg , vol.47 , pp. 278-82
    • Armstrong, D.G.1    Lavery, L.A.2    Wrobel, J.S.3    Vileikyte, L.4
  • 4
    • 14844302806 scopus 로고    scopus 로고
    • National prevalence and incidence study: 6-year sequential acute care data.
    • Whittington KT, Briones R. National prevalence and incidence study: 6-year sequential acute care data. Adv Skin Wound Care 2004;17:490-4.
    • (2004) Adv Skin Wound Care , vol.17 , pp. 490-4
    • Whittington, K.T.1    Briones, R.2
  • 6
    • 78751679075 scopus 로고    scopus 로고
    • European Pressure Ulcer Advisory Panel. A European pressure ulcer advisory panel and national pressure ulcer advisory panel collaborative guideline. [accessed on 30 March 2008].
    • European Pressure Ulcer Advisory Panel. A European pressure ulcer advisory panel and national pressure ulcer advisory panel collaborative guideline. [accessed on 30 March 2008].
  • 7
    • 9244234003 scopus 로고    scopus 로고
    • Summary report on prevalence of pressure ulcers.
    • Clark M, Bours G, Defloor T. Summary report on prevalence of pressure ulcers. EPUAP Rev 2002;4:49-57.
    • (2002) EPUAP Rev , vol.4 , pp. 49-57
    • Clark, M.1    Bours, G.2    Defloor, T.3
  • 8
    • 19044362181 scopus 로고    scopus 로고
    • Incidence and prevalence of pressure ulcers in hospice.
    • Reifsnyder J, Hoplamazian L. Incidence and prevalence of pressure ulcers in hospice. J Palliat Med 2005;8:244.
    • (2005) J Palliat Med , vol.8 , pp. 244
    • Reifsnyder, J.1    Hoplamazian, L.2
  • 9
    • 19044363947 scopus 로고    scopus 로고
    • Wounds at the end of life.
    • Tippett AW. Wounds at the end of life. Wounds 2005;17:91-8.
    • (2005) Wounds , vol.17 , pp. 91-8
    • Tippett, A.W.1
  • 10
    • 0142186755 scopus 로고    scopus 로고
    • Pressure ulcers in pediatric intensive care: incidence and factors.
    • Curley MAW, Quigley SM, Lin M. Pressure ulcers in pediatric intensive care: incidence and factors. Ped Crit Care Med 2003;4:284-384.
    • (2003) Ped Crit Care Med , vol.4 , pp. 284-384
    • Curley, M.A.W.1    Quigley, S.M.2    Lin, M.3
  • 11
    • 20444371047 scopus 로고    scopus 로고
    • Pressure ulcer prevalence in people with spinal cord injury: age-period-duration effects.
    • Chen Y, Devivo MJ, Mackson AB. Pressure ulcer prevalence in people with spinal cord injury: age-period-duration effects. Arch Phys Med Rehabil 2005;86:1208-13.
    • (2005) Arch Phys Med Rehabil , vol.86 , pp. 1208-13
    • Chen, Y.1    Devivo, M.J.2    Mackson, A.B.3
  • 12
    • 0032743904 scopus 로고    scopus 로고
    • Long-term medical complications after traumatic spinal cord injury: a regional model systems analysis.
    • McKinley WO, Jackson AB, Cardenas DD, DeVivo MJ. Long-term medical complications after traumatic spinal cord injury: a regional model systems analysis. Arch Phys Med Rehabil 1999;80:1402-10.
    • (1999) Arch Phys Med Rehabil , vol.80 , pp. 1402-10
    • McKinley, W.O.1    Jackson, A.B.2    Cardenas, D.D.3    DeVivo, M.J.4
  • 13
    • 0033181931 scopus 로고    scopus 로고
    • Hospital-acquired pressure ulcers: a comparison of costs in medical vs. surgical patients.
    • Beckrich K, Aronovitch SA. Hospital-acquired pressure ulcers: a comparison of costs in medical vs. surgical patients. Nurs Econ 1999;17:263-71.
    • (1999) Nurs Econ , vol.17 , pp. 263-71
    • Beckrich, K.1    Aronovitch, S.A.2
  • 14
    • 0034555891 scopus 로고    scopus 로고
    • Expected healing rates for chronic wounds.
    • Kantor J, Margolis DJ. Expected healing rates for chronic wounds. Wounds 2000;12:155-8.
    • (2000) Wounds , vol.12 , pp. 155-8
    • Kantor, J.1    Margolis, D.J.2
  • 15
    • 0031883039 scopus 로고    scopus 로고
    • The role of endothelial function on the foot: microcirculation and wound healing in patients with diabetes
    • Pham HT, Economides PA, Veves A. The role of endothelial function on the foot: microcirculation and wound healing in patients with diabetes. Clin Podiatr Med Surg 1998;15:85-93.
    • (1998) Clin Podiatr Med Surg , vol.15 , pp. 85-93
    • Pham, H.T.1    Economides, P.A.2    Veves, A.3
  • 16
    • 0023722586 scopus 로고
    • Skin perfusion pressure in leg ulcers assessed by photoplethysmography.
    • Buillot B, Dandurand M, Guilhou JJ. Skin perfusion pressure in leg ulcers assessed by photoplethysmography. Int Angiol 1988;7:33-4.
    • (1988) Int Angiol , vol.7 , pp. 33-4
    • Buillot, B.1    Dandurand, M.2    Guilhou, J.J.3
  • 17
    • 0027954246 scopus 로고
    • Skin microcirculatory and thermal changes in elderly subjects with early stage of pressure sores.
    • Schubert V, Perbeck L, Schubert PA. Skin microcirculatory and thermal changes in elderly subjects with early stage of pressure sores. Clin Physiol 1994;14:1-13.
    • (1994) Clin Physiol , vol.14 , pp. 1-13
    • Schubert, V.1    Perbeck, L.2    Schubert, P.A.3
  • 18
    • 78751695410 scopus 로고    scopus 로고
    • OTR3 Chronic wound healing kit CACIPLIQ20® RGTA®: The matrix therapy for regeneration. [accessed on 15 December 2009].
    • OTR3 Chronic wound healing kit CACIPLIQ20® RGTA®: The matrix therapy for regeneration. [accessed on 15 December 2009].
  • 19
    • 33646232965 scopus 로고    scopus 로고
    • Regenerating agents (RGTAs): a new therapeutic approach.
    • Review. French.
    • Barritault D, Caruelle JP. Regenerating agents (RGTAs): a new therapeutic approach. Ann Pharm Fr 2006;64:135-44. Review. French.
    • (2006) Ann Pharm Fr , vol.64 , pp. 135-44
    • Barritault, D.1    Caruelle, J.P.2
  • 21
    • 40349098374 scopus 로고    scopus 로고
    • RGTA OTR 4120, a heparan sulphate proteoglycan mimetic, increases wound breaking strength and vasodilatory capability in healing rat full-thickness excisional wounds.
    • Tong M, Zbinden MM, Hekking IJ, Vermeij M, Barritault D, Van Neck JW. RGTA OTR 4120, a heparan sulphate proteoglycan mimetic, increases wound breaking strength and vasodilatory capability in healing rat full-thickness excisional wounds. Wound Repair Regen 2008;16:294-9.
    • (2008) Wound Repair Regen , vol.16 , pp. 294-9
    • Tong, M.1    Zbinden, M.M.2    Hekking, I.J.3    Vermeij, M.4    Barritault, D.5    Van Neck, J.W.6
  • 24
    • 70350638975 scopus 로고    scopus 로고
    • Stimulated neovascularization, inflammation resolution and collagen maturation in healing rat cutaneous wounds by a heparan sulfate glycosaminoglycan mimetic, OTR4120.
    • Tong M, Tuk B, Hekking IM, Vermeij M, Barritault D, van Neck JW. Stimulated neovascularization, inflammation resolution and collagen maturation in healing rat cutaneous wounds by a heparan sulfate glycosaminoglycan mimetic, OTR4120. Wound Repair Regen 2009;17:840-52.
    • (2009) Wound Repair Regen , vol.17 , pp. 840-52
    • Tong, M.1    Tuk, B.2    Hekking, I.M.3    Vermeij, M.4    Barritault, D.5    van Neck, J.W.6
  • 25
    • 34548707915 scopus 로고    scopus 로고
    • Inter-rater reliability of Pressure Ulcer Scale for Healing (PUSH) in patients with chronic leg ulcers.
    • deGouveia Santos VL, Sellmer D, Massulo MM. Inter-rater reliability of Pressure Ulcer Scale for Healing (PUSH) in patients with chronic leg ulcers. Rev Lat Am Enfermagem 2007;15:391-6.
    • (2007) Rev Lat Am Enfermagem , vol.15 , pp. 391-6
    • deGouveia, S.V.1    Sellmer, D.2    Massulo, M.M.3
  • 26
    • 24144492402 scopus 로고    scopus 로고
    • Use of the PUSH tool to measure venous ulcer healing.
    • Ratliff CR, Rodeheaver GT. Use of the PUSH tool to measure venous ulcer healing. Ostomy Wound Manage 2005;51:58-60.
    • (2005) Ostomy Wound Manage , vol.51 , pp. 58-60
    • Ratliff, C.R.1    Rodeheaver, G.T.2
  • 28
    • 17144425043 scopus 로고    scopus 로고
    • Pressure ulcers: diagnostics and interventions aimed at wound-related complaints: a review of the literature.
    • de Laat EH, Scholte op Reimer WJ, van Achterberg T. Pressure ulcers: diagnostics and interventions aimed at wound-related complaints: a review of the literature. J Clin Nurs 2005;14:464-72.
    • (2005) J Clin Nurs , vol.14 , pp. 464-72
    • de Laat, E.H.1    Scholte op Reimer, W.J.2    van Achterberg, T.3
  • 29
    • 33644796257 scopus 로고    scopus 로고
    • The management of patients' pain in wound care.
    • Hollinworth H. The management of patients' pain in wound care. Nurs Stand 2005;20:65-6, 68, 70 passim.
    • (2005) Nurs Stand , vol.20 , pp. 65-68
    • Hollinworth, H.1
  • 31
    • 27644472236 scopus 로고    scopus 로고
    • Extracellular matrix: review of its roles in acute and chronic wounds. World Wide Wounds [accessed 1 November 2010].
    • Schultz GS, Ladwig G, Wysocki A. Extracellular matrix: review of its roles in acute and chronic wounds. World Wide Wounds 2005 [accessed 1 November 2010].
    • (2005)
    • Schultz, G.S.1    Ladwig, G.2    Wysocki, A.3
  • 32
    • 0001413484 scopus 로고    scopus 로고
    • Interactions of cytokines, growth factors, and proteases in acute and chronic wounds.
    • Mast BA, Schultz GS. Interactions of cytokines, growth factors, and proteases in acute and chronic wounds. Wound Repair Regen 1996;4:411-20.
    • (1996) Wound Repair Regen , vol.4 , pp. 411-20
    • Mast, B.A.1    Schultz, G.S.2
  • 33
    • 0034964284 scopus 로고    scopus 로고
    • Fibrin and wound healing.
    • Clark RA. Fibrin and wound healing. Ann N Y Acad Sci 2001;936:355-67.
    • (2001) Ann N Y Acad Sci , vol.936 , pp. 355-67
    • Clark, R.A.1
  • 34
    • 78751694059 scopus 로고    scopus 로고
    • The extracellular matrix in wound healing. Healthpoint Communications. [accessed 1 November 2010].
    • Haraway GD. The extracellular matrix in wound healing. Healthpoint Communications. [accessed 1 November 2010].
    • Haraway, G.D.1
  • 35
    • 62449175839 scopus 로고    scopus 로고
    • Interactiona between extracellular matrix and growth factors in wound healing.
    • Schultz GS, Wysocki A. Interactiona between extracellular matrix and growth factors in wound healing. Wound Repair Regen 2009;17:153-62.
    • (2009) Wound Repair Regen , vol.17 , pp. 153-62
    • Schultz, G.S.1    Wysocki, A.2
  • 36
    • 34250197219 scopus 로고    scopus 로고
    • The extracellular matrix in wound healing: a closer look at therapeutics for chronic wounds.
    • Agren MS, Werthen M. The extracellular matrix in wound healing: a closer look at therapeutics for chronic wounds. Lower Extrem Wounds. 2007;6:82-97.
    • (2007) Lower Extrem Wounds , vol.6 , pp. 82-97
    • Agren, M.S.1    Werthen, M.2
  • 37
    • 0036307346 scopus 로고    scopus 로고
    • A randomized, controlled trial of Promogran (a collagen/oxidized regenerated cellulose dressing) vs standard treatment in the management of diabetic foot ulcers.
    • Veves A, Sheehan P, Pham HT. A randomized, controlled trial of Promogran (a collagen/oxidized regenerated cellulose dressing) vs standard treatment in the management of diabetic foot ulcers. Arch Surg 2002;137:822-7.
    • (2002) Arch Surg , vol.137 , pp. 822-7
    • Veves, A.1    Sheehan, P.2    Pham, H.T.3
  • 38
    • 0036246719 scopus 로고    scopus 로고
    • Mechanism of action of PROMOGRAN, a protease modulating matrix, for the treatment of diabetic foot ulcers.
    • Cullen B, Smith R, McCulloch E, Silcock D, Morrison L. Mechanism of action of PROMOGRAN, a protease modulating matrix, for the treatment of diabetic foot ulcers. Wound Repair Regen 2002;10:16-25.
    • (2002) Wound Repair Regen , vol.10 , pp. 16-25
    • Cullen, B.1    Smith, R.2    McCulloch, E.3    Silcock, D.4    Morrison, L.5
  • 39
    • 0031734833 scopus 로고    scopus 로고
    • Efficacy and safety of a topical gel formulation of recombinant human platelet-derived growth factor-BB (becaplermin) in patients with chronic neuropathic diabetic ulcers: a phase III randomized placebo-controlled double-blinc study.
    • Vieman TJ, Smiell JM, Su Y. Efficacy and safety of a topical gel formulation of recombinant human platelet-derived growth factor-BB (becaplermin) in patients with chronic neuropathic diabetic ulcers: a phase III randomized placebo-controlled double-blinc study. Diabetes Care 1998;21:822-7.
    • (1998) Diabetes Care , vol.21 , pp. 822-7
    • Vieman, T.J.1    Smiell, J.M.2    Su, Y.3
  • 40
    • 0032942069 scopus 로고    scopus 로고
    • Healing of diabetic neuropathic foot ulcers receiving standard treatment: a meta-analysis.
    • Margolis DJ, Kantor J, Berlin JA. Healing of diabetic neuropathic foot ulcers receiving standard treatment: a meta-analysis. Diabetes Care 1999;22:692-5.
    • (1999) Diabetes Care , vol.22 , pp. 692-5
    • Margolis, D.J.1    Kantor, J.2    Berlin, J.A.3
  • 41
    • 0036820335 scopus 로고    scopus 로고
    • An in vitro examination of an extracellular matrix scaffold for use in wound healing.
    • Solomon DE. An in vitro examination of an extracellular matrix scaffold for use in wound healing. Int J Exp Pathol 2002;83:209-16.
    • (2002) Int J Exp Pathol , vol.83 , pp. 209-16
    • Solomon, D.E.1
  • 42
    • 0034904048 scopus 로고    scopus 로고
    • Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.
    • Vlodavshy I, Friedman Y. Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis. J Clin Invest 2001;108:341-7.
    • (2001) J Clin Invest , vol.108 , pp. 341-7
    • Vlodavshy, I.1    Friedman, Y.2
  • 43
    • 78751694969 scopus 로고    scopus 로고
    • ® The matrix therapy for regeneration. [accessed on 15 December 2009].
    • ® The matrix therapy for regeneration. 2009: [accessed on 15 December 2009].
    • (2009)
  • 45
    • 34250197219 scopus 로고    scopus 로고
    • The extracellular matrix in wound healing: a closer look at therapeutics for chronic wounds.
    • Agren MS, Werthén M. The extracellular matrix in wound healing: a closer look at therapeutics for chronic wounds. Int J Low Extrem Wounds 2007;6:82-97.
    • (2007) Int J Low Extrem Wounds , vol.6 , pp. 82-97
    • Agren, M.S.1    Werthén, M.2
  • 46
    • 34250667632 scopus 로고    scopus 로고
    • Extracellular matrix as a strategy for treating chronic wounds.
    • Hodde JP, Johnson CE. Extracellular matrix as a strategy for treating chronic wounds. Am J Clin Dermatol 2007;8:61-6.
    • (2007) Am J Clin Dermatol , vol.8 , pp. 61-6
    • Hodde, J.P.1    Johnson, C.E.2
  • 47
    • 0032894047 scopus 로고    scopus 로고
    • A substituted dextran enhances muscle fiber survival and regeneration in ischemic and denervated rat EDL muscle.
    • Desgranges P, Barbaud C, Caruelle JP, Barritault D, Gautron J. A substituted dextran enhances muscle fiber survival and regeneration in ischemic and denervated rat EDL muscle. FASEB J 1999;13:761-6.
    • (1999) FASEB J , vol.13 , pp. 761-6
    • Desgranges, P.1    Barbaud, C.2    Caruelle, J.P.3    Barritault, D.4    Gautron, J.5
  • 50
    • 78751690000 scopus 로고    scopus 로고
    • Structurally different RGTAs modulate collagen-type expression by cultured aortic smoot muscle cells via different pathways involving fibroblast growth factor-2 or transforming growth factor-1. The FASEB j-FJ Express ; Available at: [accessed 1 April 2008].
    • Alexakis C, Mestries P, Garcia S, Petit E, Barbier V, Papy-Garcia D, Sagot MA, Barritault D, Caruelle JP, Kern P. Structurally different RGTAs modulate collagen-type expression by cultured aortic smoot muscle cells via different pathways involving fibroblast growth factor-2 or transforming growth factor-1. The FASEB j-FJ Express 2008; Available at: [accessed 1 April 2008].
    • (2008)
    • Alexakis, C.1    Mestries, P.2    Garcia, S.3    Petit, E.4    Barbier, V.5    Papy-Garcia, D.6    Sagot, M.A.7    Barritault, D.8    Caruelle, J.P.9    Kern, P.10
  • 51
    • 0018748167 scopus 로고
    • Experimental skin necrosis produced by adriamycin.
    • Rudolph R, Suzuki M, Luce JK. Experimental skin necrosis produced by adriamycin. Cancer Treat Rep 1979;63:529-37.
    • (1979) Cancer Treat Rep , vol.63 , pp. 529-37
    • Rudolph, R.1    Suzuki, M.2    Luce, J.K.3
  • 53
    • 78751693652 scopus 로고    scopus 로고
    • Matrix therapy in vascular pathology: first pilot study to evaluate RGTA Cacipliq 20. Abstract at Toronto 2nd World Union of Wound Healing Society meeting; June - [accessed on 1 November 2010].
    • Barritault D, Allaire E, Louissaint T, Kichenin K, Godeau B, Becquemin JP, Desgranges P. Matrix therapy in vascular pathology: first pilot study to evaluate RGTA Cacipliq 20. Abstract at Toronto 2nd World Union of Wound Healing Society meeting; 2008 June 2-4 [accessed on 1 November 2010].
    • (2008) , pp. 2-4
    • Barritault, D.1    Allaire, E.2    Louissaint, T.3    Kichenin, K.4    Godeau, B.5    Becquemin, J.P.6    Desgranges, P.7
  • 54
    • 45549085579 scopus 로고    scopus 로고
    • A comparative study of the use of exsikines and other advanced wound care products/modalities in the treatment of various wound types in efficacy.
    • Walker MJ. A comparative study of the use of exsikines and other advanced wound care products/modalities in the treatment of various wound types in efficacy. Adv Skin Wound Care 2008;21:218-26.
    • (2008) Adv Skin Wound Care , vol.21 , pp. 218-26
    • Walker, M.J.1
  • 55
    • 55949123988 scopus 로고    scopus 로고
    • Activated, Type I collagen (CellerateRx) and its effectiveness in healing recalcitrant diabetic wounds: a case presentation.
    • Newman MI, Baratta LG, Swartz K. Activated, Type I collagen (CellerateRx) and its effectiveness in healing recalcitrant diabetic wounds: a case presentation. Adv Skin Wound Care 2008;21:370-4.
    • (2008) Adv Skin Wound Care , vol.21 , pp. 370-4
    • Newman, M.I.1    Baratta, L.G.2    Swartz, K.3
  • 56
    • 33746677591 scopus 로고    scopus 로고
    • The clinical efficacy and cost effectiveness of the vacuum-assisted closure technique in the management of acute and chronic wounds: a randomized controlled trial.
    • Braakenburg A, Obdeign MC, Feitz R, van Rooij I, van Griethuysen AJ, Klinkenbijl J. The clinical efficacy and cost effectiveness of the vacuum-assisted closure technique in the management of acute and chronic wounds: a randomized controlled trial. J Plas Reconstr Surg 2006;118:390-7.
    • (2006) J Plas Reconstr Surg , vol.118 , pp. 390-7
    • Braakenburg, A.1    Obdeign, M.C.2    Feitz, R.3    van Rooij, I.4    van Griethuysen, A.J.5    Klinkenbijl, J.6
  • 57
    • 34247631246 scopus 로고    scopus 로고
    • Comparing conventional gauze therapy to vacuum-assisted closure wound therapy: a prospective randomized trial.
    • Moues CM, van den Bemd GJCM, Heule F, Hovius SER. Comparing conventional gauze therapy to vacuum-assisted closure wound therapy: a prospective randomized trial. J Plas Reconstruc Aesth Surg 2007;60:672-81.
    • (2007) J Plas Reconstruc Aesth Surg , vol.60 , pp. 672-81
    • Moues, C.M.1    van den Bemd, G.J.C.M.2    Heule, F.3    Hovius, S.E.R.4
  • 58
    • 7444246133 scopus 로고    scopus 로고
    • Etiology and incidence of rehospitalization after traumatic spinal cord injury: a multicenter analysis.
    • Cardenas DD, Hoffman JM, Kirshblum S, McKinley W. Etiology and incidence of rehospitalization after traumatic spinal cord injury: a multicenter analysis. Arch Phys Med Rehabil 2004;85:1757-63.
    • (2004) Arch Phys Med Rehabil , vol.85 , pp. 1757-63
    • Cardenas, D.D.1    Hoffman, J.M.2    Kirshblum, S.3    McKinley, W.4
  • 60
    • 78751689446 scopus 로고    scopus 로고
    • Wound healing, chronic wounds. October 9, 2008 [accessed 21 May 2009].
    • De la Torre JI, Chambers JA. Wound healing, chronic wounds. October 9, 2008 [accessed 21 May 2009].
    • De la Torre, J.I.1    Chambers, J.A.2
  • 62
    • 33745514509 scopus 로고    scopus 로고
    • Clinical approach to wounds: debridement and wound bed preparation including the use of dressings and wound-healing adjuvants.
    • Attinger CE, Janis FE, Steinberg J, Schwartz J, Al-Attar A, Couch K. Clinical approach to wounds: debridement and wound bed preparation including the use of dressings and wound-healing adjuvants. Plast Reconstr Surg 2006;117:72S-109S.
    • (2006) Plast Reconstr Surg , vol.117
    • Attinger, C.E.1    Janis, F.E.2    Steinberg, J.3    Schwartz, J.4    Al-Attar, A.5    Couch, K.6
  • 63
    • 0033835647 scopus 로고    scopus 로고
    • Wound healing trajectories as predictors of effectiveness of therapeutic agents.
    • Robson MC, Hill DP, Woodske ME, Steed DL. Wound healing trajectories as predictors of effectiveness of therapeutic agents. Arch Surg 2001;135:773.
    • (2001) Arch Surg , vol.135 , pp. 773
    • Robson, M.C.1    Hill, D.P.2    Woodske, M.E.3    Steed, D.L.4
  • 64
  • 65
    • 27144530001 scopus 로고    scopus 로고
    • The use of topical opioids to relieve pressure ulcer pain.
    • Ashfield T. The use of topical opioids to relieve pressure ulcer pain. Nurs Stand 2005;19:90-2.
    • (2005) Nurs Stand , vol.19 , pp. 90-2
    • Ashfield, T.1
  • 66
    • 0037716743 scopus 로고    scopus 로고
    • Pilot study to determine the effectiveness of diamorphine gel to control pressure ulcer pain.
    • Flock P. Pilot study to determine the effectiveness of diamorphine gel to control pressure ulcer pain. J Pain Symptom Manage 2003;25:547-54.
    • (2003) J Pain Symptom Manage , vol.25 , pp. 547-54
    • Flock, P.1
  • 68
    • 0038392855 scopus 로고    scopus 로고
    • Analgesic efficacy of morphine applied topically to painful ulcers.
    • Zeppetella G, Paul J, Ribeiro MD. Analgesic efficacy of morphine applied topically to painful ulcers. J Pain Symptom Manage 2003;25:555-8.
    • (2003) J Pain Symptom Manage , vol.25 , pp. 555-8
    • Zeppetella, G.1    Paul, J.2    Ribeiro, M.D.3
  • 69
    • 0034885972 scopus 로고    scopus 로고
    • Prevention and treatment of pressure ulcers: what works? what doesn't?.
    • 710-14, 717-22.
    • Thomas DR. Prevention and treatment of pressure ulcers: what works? what doesn't?. Cleve Clin J Med 2001;68:704-7, 710-14, 717-22.
    • (2001) Cleve Clin J Med , vol.68 , pp. 704-7
    • Thomas, D.R.1
  • 70
    • 84921702173 scopus 로고    scopus 로고
    • Topical agents or dressings for pain in venous leg ulcers.
    • 1):CD001177. DOI: 10.1002/14651858.CD001177..
    • Briggs M, Nelson EA. Topical agents or dressings for pain in venous leg ulcers. Cochrane Database Syst Rev 2003;(1):CD001177. DOI: 10.1002/14651858.CD001177..
    • (2003) Cochrane Database Syst Rev
    • Briggs, M.1    Nelson, E.A.2
  • 71
    • 0141429947 scopus 로고    scopus 로고
    • Living with a chronic leg ulcer: an insight into patients' experiences and feelings.
    • Douglas V. Living with a chronic leg ulcer: an insight into patients' experiences and feelings. J Wound Care 2001;10:355-60.
    • (2001) J Wound Care , vol.10 , pp. 355-60
    • Douglas, V.1
  • 72
    • 35348914603 scopus 로고    scopus 로고
    • Best practice recommendations for the prevention and treatment of pressure ulcers: update 2006.
    • quiz 461-2
    • Keast DH, Parslow N, Houghton PE, Norton L, Fraser C. Best practice recommendations for the prevention and treatment of pressure ulcers: update 2006. Adv Skin Wound Care 2007;20:447-60. quiz 461-2
    • (2007) Adv Skin Wound Care , vol.20 , pp. 447-60
    • Keast, D.H.1    Parslow, N.2    Houghton, P.E.3    Norton, L.4    Fraser, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.