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Volumn 2, Issue 1, 2011, Pages 3-4

ACS chemical neuroscience spotlight on CEP-1347

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BIOLOGICAL MARKER; CEP 1347; DOPAMINE; DOPAMINE TRANSPORTER; K 252A; MIXED LINEAGE KINASE; STRESS ACTIVATED PROTEIN KINASE;

EID: 78751671550     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn1000793     Document Type: Article
Times cited : (13)

References (8)
  • 3
    • 0036139987 scopus 로고    scopus 로고
    • Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons
    • Harris, C. A., Deshmukh, M., Tsui-Pierchala, B., Maroney, A. C., and Johnson, E. M., Jr. (2002) Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons J. Neurosci. 22 (1) 103-13
    • (2002) J. Neurosci. , vol.22 , Issue.1 , pp. 103-13
    • Harris, C.A.1    Deshmukh, M.2    Tsui-Pierchala, B.3    Maroney, A.C.4    Johnson Jr., E.M.5
  • 4
    • 0033029823 scopus 로고    scopus 로고
    • CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons in vivo
    • Saporito, M. S., Brown, E. M., Miller, M. S., and Carswell, S. (1999) CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons in vivo J. Pharmacol. Exp. Ther. 288 (2) 421-7
    • (1999) J. Pharmacol. Exp. Ther. , vol.288 , Issue.2 , pp. 421-7
    • Saporito, M.S.1    Brown, E.M.2    Miller, M.S.3    Carswell, S.4
  • 5
    • 0036988312 scopus 로고    scopus 로고
    • Discovery of CEP-1347/KT-7515, an inhibitor of the JNK/SAPK pathway for the treatment of neurodegenerative diseases
    • Saporito, M. S., Hudkins, R. L., and Maroney, A. C. (2002) Discovery of CEP-1347/KT-7515, an inhibitor of the JNK/SAPK pathway for the treatment of neurodegenerative diseases Prog. Med. Chem. 40, 23-62
    • (2002) Prog. Med. Chem. , vol.40 , pp. 23-62
    • Saporito, M.S.1    Hudkins, R.L.2    Maroney, A.C.3
  • 6
    • 0842324952 scopus 로고    scopus 로고
    • The safety and tolerability of a mixed lineage kinase inhibitor (CEP-1347) in PD
    • Parkinson Study Group
    • Parkinson Study Group (2004) The safety and tolerability of a mixed lineage kinase inhibitor (CEP-1347) in PD Neurology 62 (2) 330-2
    • (2004) Neurology , vol.62 , Issue.2 , pp. 330-2
  • 7
    • 35148882113 scopus 로고    scopus 로고
    • Mixed lineage kinase inhibitor CEP-1347 fails to delay disability in early Parkinson disease
    • The Parkinson Study Group PRECEPT Investigators
    • The Parkinson Study Group PRECEPT Investigators (2007) Mixed lineage kinase inhibitor CEP-1347 fails to delay disability in early Parkinson disease Neurology 69 (15) 1480-90
    • (2007) Neurology , vol.69 , Issue.15 , pp. 1480-90
  • 8
    • 77953666105 scopus 로고    scopus 로고
    • Genetic animal models of Parkinson's disease
    • Dawson, T. M., Ko, H. S., and Dawson, V. L. (2010) Genetic animal models of Parkinson's disease Neuron 66 (5) 646-61
    • (2010) Neuron , vol.66 , Issue.5 , pp. 646-61
    • Dawson, T.M.1    Ko, H.S.2    Dawson, V.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.