Postischemic treatment with ethyl pyruvate prevents adenosine triphosphate depletion, ameliorates inflammation, and decreases thrombosis in a murine model of hind-limb ischemia and reperfusion

Journal of Trauma - Injury, Infection and Critical Care

Volumn 70, Issue 1, 2011, Pages 103-110

  Crawford, Robert S ^a   Albadawi, Hassan ^a   Atkins, Marvin D ^a   Jones, John J ^a   Conrad, Mark F ^a   Austen, William G ^a   Fink, Mitchell P ^b   Watkins, Michael T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

cytokines; Inflammation; Ischemia reperfusion; Skeletal muscle

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHEMOATTRACTANT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; PYRUVIC ACID DERIVATIVE; PYRUVIC ACID ETHYL ESTER; RINGER LACTATE SOLUTION; THROMBIN ANTITHROMBIN COMPLEX; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HINDLIMB; HISTOPATHOLOGY; INFLAMMATION; LIMB ISCHEMIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; REPERFUSION INJURY; SKELETAL MUSCLE; THROMBOSIS;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTITHROMBIN III; DISEASE MODELS, ANIMAL; INFLAMMATION; INTERLEUKIN-1; LACTATES; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; PEPTIDE HYDROLASES; PEROXIDASE; PYRUVATES; REPERFUSION INJURY; THROMBOSIS;

EID: 78751629536     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e3182031ccb     Document Type: Article

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